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Featured Greenville 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $377 per night from Nov 30 to Dec 1
CA $377
CA $426 total
Nov 30 - Dec 1
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (405 reviews)
Will definitely be back !!

Reviewed on Nov 11, 2025

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is CA $212 per night from Nov 19 to Nov 20
CA $212
CA $281 total
Nov 19 - Nov 20
includes taxes & fees
Stay at this 4-star spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (612 reviews)
Staff was professional and courteous. Amazing room and resort amenities.

Reviewed on Nov 11, 2025

Opens in a new windowHotel Hartness
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $251 per night from Nov 25 to Nov 26
CA $251
CA $276 total
Nov 25 - Nov 26
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,000 reviews)
Y

Reviewed on Nov 9, 2025

Opens in a new windowThe Westin Poinsett Greenville
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is CA $147 per night from Nov 28 to Nov 29
CA $147
CA $162 total
Nov 28 - Nov 29
includes taxes & fees
Stay at this 4-star business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (603 reviews)
Staff were friendly and helpful. Breakfast was good. Location was good. The property is reaching a point were it could use a refresh.

Reviewed on Oct 12, 2025

Opens in a new windowGreenville Marriott
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4 out of 5
101 Falls Park Dr Greenville SC
The price is CA $167 per night from Nov 30 to Dec 1
CA $167
CA $189 total
Nov 30 - Dec 1
includes taxes & fees
Stay at this apartment in Greenville. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (761 reviews)
Great location. Easy check-in/check-out. Questions answered promptly via phone call or text. Plenty of room and privacy for guests.

Reviewed on Nov 7, 2025

Opens in a new windowMint House Greenville - Downtown
Park Place Apartments by Landing

Park Place Apartments by Landing

4 out of 5
31 Victor St Greenville SC
Stay at this 4-star aparthotel in Greenville. Enjoy free parking, a 24-hour fitness center, and in-room washers/dryers. Popular attractions Bon Secours Wellness ...
7.6/10 Good! (40 reviews)
Great access to bike trail. No working elevator and 3 flights of stairs with luggage is a challenge.

Reviewed on Jun 19, 2025

Opens in a new windowPark Place Apartments by Landing
Randall St , 202/204

Randall St , 202/204

4 out of 5
202 Randall Street Greenville SC
Stay at this 4-star family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new windowRandall St , 202/204
34 Allen St

34 Allen St

4 out of 5
34 Allen Street Greenville SC
Stay at this 4-star family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Falls Park on the Reedy and ...
Opens in a new window34 Allen St
140 Catlin Circle

140 Catlin Circle

4 out of 5
140 Catlin Circle Greenville SC
Stay at this 4-star family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new window140 Catlin Circle
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4 Star Hotels Greenville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Greenville hotel reviews by fellow wanderers