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Featured Greenville 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $339 per night from Feb 22 to Feb 23
CA $339
CA $383 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (445 reviews)
Beautiful as soon you walk in and the rooms were great. Great location.

Reviewed on Feb 7, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $271 per night from Mar 15 to Mar 16
CA $271
CA $298 total
Mar 15 - Mar 16
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,000 reviews)
A dream come true since I was young to stay here. It truly was a lovely Christmas Eve.

Reviewed on Feb 6, 2026

Opens in a new windowThe Westin Poinsett Greenville
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $206 per night from Feb 22 to Feb 23
CA $206
CA $273 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (647 reviews)
The friendliest and warm environment. Its a beautiful hotel and amazing food and drinks! Highly recommend it! I'm definitely returning.

Reviewed on Feb 10, 2026

Opens in a new windowHotel Hartness
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $166 per night from Feb 27 to Feb 28
CA $166
CA $183 total
Feb 27 - Feb 28
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (623 reviews)
Clean rooms, clean facility, issues dealt with in minutes, and a tasty breakfast buffet.

Reviewed on Feb 9, 2026

Opens in a new windowGreenville Marriott
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4 out of 5
101 Falls Park Dr Greenville SC
The price is CA $152 per night from Feb 23 to Feb 24
CA $152
CA $168 total
Feb 23 - Feb 24
includes taxes & fees
Stay at this apartment in Greenville. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (793 reviews)
Room was amazing. It was like having a one bedroom condo in downtown Greenville. Great spot

Reviewed on Feb 6, 2026

Opens in a new windowMint House Greenville - Downtown
Park Place Apartments by Landing

Park Place Apartments by Landing

4 out of 5
31 Victor St Greenville SC
Stay at this aparthotel in Greenville. Enjoy free parking, a 24-hour fitness center, and in-room washers/dryers. Popular attractions Bon Secours Wellness Arena ...
7.6/10 Good! (46 reviews)
This is an extended stay type of apartment - not a hotel. No front desk. When I arrived - there was not a key to get into the building. It was supposed to be in a lockbox outside but that was open and empty! You have to walk up at least one flight of stairs - not ideal for an extended stay where ...

Reviewed on Dec 4, 2025

Opens in a new windowPark Place Apartments by Landing
Randall St , 202/204

Randall St , 202/204

4 out of 5
202 Randall Street Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new windowRandall St , 202/204
140 Catlin Circle

140 Catlin Circle

4 out of 5
140 Catlin Circle Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new window140 Catlin Circle
34 Allen St

34 Allen St

4 out of 5
34 Allen Street Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new window34 Allen St
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4 Star Hotels Greenville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Greenville hotel reviews by fellow wanderers