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Featured Guayaquil 4 Star hotels

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from Apr 5 to Apr 6
CA $139
CA $156 total
Apr 5 - Apr 6
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,000 reviews)
The complimentary airport shuttle service was excellent and very helpful, especially for very late arrival flights. The shuttle driver would hold a sign with your name waiting for you. The breakfast was very good.

Reviewed on Apr 2, 2026

Opens in a new windowWyndham Guayaquil Puerto Santa Ana
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
The price is CA $135 per night from Apr 19 to Apr 20
CA $135
CA $152 total
Apr 19 - Apr 20
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowHilton Colon Guayaquil
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $90 per night from Apr 4 to Apr 5
CA $90
CA $103 total
Apr 4 - Apr 5
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
9.2/10 Wonderful! (1,000 reviews)
Clean, very comfortable bed .Centrally located, near touristy places . I will stay again

Reviewed on Apr 1, 2026

Opens in a new windowUnipark by Oro Verde Hotels
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 out of 5
Av. Joaquín Orrantia y L. Benitez Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $117 per night from Apr 5 to Apr 6
CA $117
CA $133 total
Apr 5 - Apr 6
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in our ...
9/10 Wonderful! (1,000 reviews)
no cuartos limpios

Reviewed on Mar 30, 2026

Opens in a new windowTRYP by Wyndham Guayaquil Airport
Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport

4 out of 5
Av 33. Ciudadela La Garzota Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $70 per night from Apr 8 to Apr 9
CA $70
CA $72 total
Apr 8 - Apr 9
Book a stay at this family-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (246 reviews)
The staff was very helpful, they got us taxis to the airport at 3 am, and made sure we were all taken care of.

Reviewed on Mar 30, 2026

Opens in a new windowHotel Puerto Pacifico Guayaquil Airport
Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel

4 out of 5
Boyaca 1615 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $100 per night from Apr 3 to Apr 4
CA $100
CA $112 total
Apr 3 - Apr 4
Book a stay at this family-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
9.2/10 Wonderful! (1,003 reviews)
The breakfast was a fresh menu and selection

Reviewed on Mar 27, 2026

Opens in a new windowGrand Hotel Guayaquil, an Ascend Collection Hotel
Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil

4 out of 5
Av Malecon Simon Bolivar Guayaquil
Fully refundableReserve now, pay when you stay
The price is CA $83 per night from Apr 4 to Apr 5
CA $83
CA $94 total
Apr 4 - Apr 5
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (294 reviews)
Thank

Reviewed on Mar 29, 2026

Opens in a new windowIbis Styles El Malecon Guayaquil
Hotel Palace Guayaquil

Hotel Palace Guayaquil

4 out of 5
Chile No # 214 y Luque Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $82 per night from Apr 5 to Apr 6
CA $82
CA $93 total
Apr 5 - Apr 6
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (925 reviews)
Good

Reviewed on Mar 28, 2026

Opens in a new windowHotel Palace Guayaquil
Hotel del Parque

Hotel del Parque

4.5 out of 5
Parque Histórico de Guayaquil, Km 1.5 Samborondon Guayas
Fully refundableReserve now, pay when you stay
The price is CA $595 per night from Apr 6 to Apr 7
CA $595
CA $655 total
Apr 6 - Apr 7
Book a stay at this luxury hotel in Samborondon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Guayaquil Historic Park and Museum of ...
Opens in a new windowHotel del Parque
Hotel The Royalty Inn

Hotel The Royalty Inn

4 out of 5
Cdla. Simón Bolivar Mz. 28 Sl. 19 Guayaquil
Fully refundableReserve now, pay when you stay
The price is CA $67 per night from Apr 27 to Apr 28
CA $67
CA $97 total
Apr 27 - Apr 28
Stay at this guesthouse in Guayaquil. Enjoy free WiFi, a 24-hour front desk, and airport drop-off service (surcharge). Popular attractions Mall del Sol Shopping ...
Opens in a new windowHotel The Royalty Inn
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4 Star Hotels Guayaquil

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Guayaquil 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Guayaquil will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Guayaquil, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Guayaquil hotel reviews by fellow wanderers