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Featured Key West 4 Star hotels

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

4 out of 5
3820 North Roosevelt Boulevard Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $188 per night from Jun 15 to Jun 16
CA $188
CA $290 total
Jun 15 - Jun 16
includes taxes & fees
Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,381 reviews)
"Todo excelente , muy buena atención , buena limpieza"

Reviewed on Jun 13, 2026

Opens in a new windowBlue Flamingo Resort Key West
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $285 per night from Jun 22 to Jun 23
CA $285
CA $423 total
Jun 22 - Jun 23
includes taxes & fees
Book a stay at this beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (3,396 reviews)
"Amazing place to stay"

Reviewed on Jun 14, 2026

Opens in a new windowSouthernmost Beach Resort and Guesthouses
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

4 out of 5
601 Front St Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $278 per night from Jun 21 to Jun 22
CA $278
CA $411 total
Jun 21 - Jun 22
includes taxes & fees
Book a stay at this beach resort in Key West. Enjoy free WiFi, a full-service spa, and a marina. Our guests praise the pool and the helpful staff in our reviews. ...
9/10 Wonderful! (1,009 reviews)
"Property was clean, had an excellent restaurant on site, and a small private beach."

Reviewed on Jun 13, 2026

Opens in a new windowHyatt Centric Key West Resort and Spa
Margaritaville Beach House Key West

Margaritaville Beach House Key West

4 out of 5
2001 South Roosevelt Boulevard Key West FL
The price is CA $315 per night from Jun 29 to Jun 30
CA $315
CA $443 total
Jun 29 - Jun 30
includes taxes & fees
Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ...
Opens in a new windowMargaritaville Beach House Key West
Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton

4 out of 5
1500 Reynolds Street Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $324 per night from Jun 21 to Jun 22
CA $324
CA $459 total
Jun 21 - Jun 22
includes taxes & fees
Book a stay at this beach resort in Key West. Enjoy 2 outdoor pools, a full-service spa, and a private beach. Popular attractions Southernmost Point and Duval ...
8.6/10 Excellent! (709 reviews)
"The ambiance of the old building was unique. The staff were very attentive and accommodating. The grounds were mostly clean and well kept. There were some areas that needed attention or were worn. Our room was very clean and well kept. All in all it was a nice stay. Nothing special. But ..."

Reviewed on Jun 13, 2026

Opens in a new windowCasa Marina Key West, Curio Collection by Hilton
Pier House Resort & Spa

Pier House Resort & Spa

4 out of 5
1 Duval St Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $373 per night from Jun 24 to Jun 25
CA $373
CA $518 total
Jun 24 - Jun 25
includes taxes & fees
Book a stay at this beach resort in Key West. Enjoy a full-service spa, a private beach, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,178 reviews)
"Everything was good except the shower in the accessable room we had. Water ran everywhere all over the bathroom every time we took a shower. Was not pleased that the restaurant s and bars went cashless."

Reviewed on Jun 12, 2026

Opens in a new windowPier House Resort & Spa
Havana Cabana at Key West

Havana Cabana at Key West

4 out of 5
3420 N. Roosevelt Blvd Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $195 per night from Jun 29 to Jun 30
CA $195
CA $311 total
Jun 29 - Jun 30
includes taxes & fees
Book a stay at this business-friendly hotel in Key West. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (1,814 reviews)
"N/A"

Reviewed on Jun 13, 2026

Opens in a new windowHavana Cabana at Key West
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

4 out of 5
430 Duval St Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $332 per night from Jun 28 to Jun 29
CA $332
CA $420 total
Jun 28 - Jun 29
includes taxes & fees
Book a stay at this business-friendly hotel in Key West. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (417 reviews)
"The hotel is in a great location. There were a few issues: I booked a king room But they gave us 2 queen beds plus the internet never worked so no streaming Netflix, prime or tv. They sent engineers to our room several times but never got it to work. I wish there was a hot tub but there isn’t and ..."

Reviewed on Jun 8, 2026

Opens in a new windowLa Concha Key West, Autograph Collection
DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West

4 out of 5
3990 S Roosevelt Blvd Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $189 per night from Jun 21 to Jun 22
CA $189
CA $259 total
Jun 21 - Jun 22
includes taxes & fees
Book a stay at this business-friendly resort in Key West. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,043 reviews)
"Room was clean, staff were friendly and helpful. Hotel was a little further from attractions than I expected but was still a great place to stay."

Reviewed on Jun 9, 2026

Opens in a new windowDoubleTree Resort by Hilton Grand Key - Key West
Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

4 out of 5
245 Front Street Key West FL
Fully refundableReserve now, pay when you stay
The price is CA $362 per night from Jun 23 to Jun 24
CA $362
CA $463 total
Jun 23 - Jun 24
includes taxes & fees
Stay at this hotel in Key West. Enjoy a marina, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.2/10 Wonderful! (1,129 reviews)
"Very beautiful and clean place to stay. We had an ocean view room, and it was amazing. The bed was very comfortable and the rooms were very clean. Definitely worth the money to stay at this property. We did not use the pool, but we noticed a lot of guests enjoying it each day .The food at the on ..."

Reviewed on Jun 13, 2026

Opens in a new windowOpal Key Resort & Marina, Key West
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4 Star Hotels Key West

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Key West 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Key West will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Key West, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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