Find and compare 4 Star hotels in Spartanburg

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Featured Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $444 per night from Apr 5 to Apr 6
CA $444
CA $501 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.6/10 Exceptional! (468 reviews)
Beautiful place

Reviewed on Mar 26, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $223 per night from Apr 26 to Apr 27
CA $223
CA $292 total
Apr 26 - Apr 27
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (686 reviews)
Beautiful grounds

Reviewed on Apr 1, 2026

Opens in a new windowHotel Hartness
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $263 per night from Apr 5 to Apr 6
CA $263
CA $289 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,001 reviews)
Valet parking was much easier but significantly more expensive.

Reviewed on Mar 20, 2026

Opens in a new windowThe Westin Poinsett Greenville
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $178 per night from Apr 12 to Apr 13
CA $178
CA $202 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.6/10 Excellent! (636 reviews)
Clean rooms, great atmosphere

Reviewed on Mar 29, 2026

Opens in a new windowGreenville Marriott
Landing Apartments Greer - Sugar Creek

Landing Apartments Greer - Sugar Creek

4 out of 5
3000 Daventry Cir Greer SC
Book a stay at this business-friendly apartment in Greer. Enjoy free parking, an outdoor pool, and a fitness center. Popular attractions Century Park and Crossland ...
Opens in a new windowLanding Apartments Greer - Sugar Creek
Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport

4 out of 5
125 The Parkway Greer SC
Fully refundableReserve now, pay when you stay
The price is CA $186 per night from Apr 26 to Apr 27
CA $186
CA $204 total
Apr 26 - Apr 27
includes taxes & fees
Stay at this hotel in Greer. Enjoy free parking, breakfast (surcharge), and room service. Popular attractions Thornblade Tennis Center and Topgolf Greenville ...
10/10 Exceptional! (2 reviews)
This work trip was last minute and no hotels were available. This one popped up and I was nervous bc I had never seen it before. That’s because it had only been open 4 days! I couldn’t believe my luck. It was perfect! Perfect food! Perfect hospitality! Perfect room!

Reviewed on Mar 23, 2026

Opens in a new windowDoubletree By Hilton Greenville Airport
Landing Apartments - Lyman

Landing Apartments - Lyman

4 out of 5
610 Universal Drive Lyman SC
Book a stay at this business-friendly aparthotel in Lyman. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Lyman Amphitheater and Lyman ...
Opens in a new windowLanding Apartments - Lyman
140 Catlin Circle

140 Catlin Circle

4 out of 5
140 Catlin Circle Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new window140 Catlin Circle
Randall St , 202/204

Randall St , 202/204

4 out of 5
202 Randall Street Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new windowRandall St , 202/204
Don't see what you're looking for?
See all available properties in Spartanburg
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Spartanburg hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity