Find and compare 4 Star hotels in Spartanburg

Start date: Check-in selected.
To Date
End date: Check-out

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Featured Spartanburg 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $314 per night from Jan 21 to Jan 22
CA $314
CA $354 total
Jan 21 - Jan 22, 2026
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9.4/10 Exceptional! (428 reviews)
Awesome place.

Reviewed on Dec 31, 2025

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $245 per night from Jan 4 to Jan 5
CA $245
CA $270 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,004 reviews)
Staff was excellent. Holiday decorations and bar were stupendous. The lobby was quite festive for a holiday cocktail.

Reviewed on Dec 27, 2025

Opens in a new windowThe Westin Poinsett Greenville
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $220 per night from Jan 5 to Jan 6
CA $220
CA $288 total
Jan 5 - Jan 6, 2026
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (631 reviews)
Wonderful

Reviewed on Dec 16, 2025

Opens in a new windowHotel Hartness
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from Jan 9 to Jan 10
CA $139
CA $152 total
Jan 9 - Jan 10, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (612 reviews)
Bed was SO comfortable, I slept all through the night!!! Staff incredible especially the girls at breakfast and Adam at the bar.

Reviewed on Dec 19, 2025

Opens in a new windowGreenville Marriott
Doubletree By Hilton Greenville Airport

Doubletree By Hilton Greenville Airport

4 out of 5
125 The Parkway Greer SC
Stay at this hotel in Greer. Enjoy free parking, breakfast (surcharge), and room service. Popular attractions Haywood Mall and Thornblade Tennis Center are located ...
Opens in a new windowDoubletree By Hilton Greenville Airport
Randall St , 202/204

Randall St , 202/204

4 out of 5
202 Randall Street Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new windowRandall St , 202/204
140 Catlin Circle

140 Catlin Circle

4 out of 5
140 Catlin Circle Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Bon Secours Wellness Arena ...
Opens in a new window140 Catlin Circle
Don't see what you're looking for?
See all available properties in Spartanburg
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Spartanburg

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Spartanburg 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Spartanburg will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Spartanburg, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Spartanburg hotel reviews by fellow wanderers