Find and compare 4 Star hotels in Syracuse

Name: Eureka Palace Hotel Spa
Price range: CA $144
Rating: 8

Wander Wisely with exceptional service, 24/7 support

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Featured Syracuse 4 Star hotels

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR

Fully refundableReserve now, pay when you stay

CA $359

CA $411 total

Aug 29 - Aug 30

includes taxes & fees

Book a stay at this family-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the breakfast and the helpful ...

9.6/10 Exceptional! (1,014 reviews)

"Everything was great Staff was amazing very helpful Breakfast was very good"

Reviewed on Aug 23, 2026

Dolce by Wyndham Siracusa I Monasteri Golf & Spa

Traversa Monasteri Di Sotto, 3 Syracuse SR

Fully refundable

CA $129

CA $147 total

Sep 6 - Sep 7

includes taxes & fees

Book a stay at this golf hotel in Syracuse. Enjoy free WiFi, free parking, and a golf course. Popular attractions Castello Eurialo and Aretusa Park are located ...

7.4/10 Good! (42 reviews)

"Great upgrade Wonderful place"

Reviewed on Nov 15, 2025

UNA Hotels One Siracusa Wellness & SPA

Via Diodoro Siculo 4 Syracuse SR

Fully refundableReserve now, pay when you stay

CA $191

CA $218 total

Aug 31 - Sep 1

includes taxes & fees

Book a stay at this spa hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.6/10 Excellent! (550 reviews)

"It’s a really beautiful hotel. Great staff, great food, AC works, beautiful spa. It’s in central place but not in the midst of all the chaos at the same time!"

Reviewed on Jul 15, 2026

Hotel Parco delle Fontane

Viale Scala Greca, 325 Syracuse SR

Fully refundableReserve now, pay when you stay

CA $193

CA $220 total

Aug 26 - Aug 27

includes taxes & fees

Book a stay at this business-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Rope-makers' Cave and Latomia ...

9.2/10 Wonderful! (303 reviews)

"Very nice hotel outside of busy area but easy to access downtown Ortigia and Siracusa Unfortunately was only there for one night but pool looked wonderful and historic ambiance in hotel was interesting to see. Parking was free and breakfast was wonderful with so many options! Will definitely revisit ..."

Reviewed on Jul 9, 2026

Grand Hotel Villa Politi

Via Maria Politi Laudien 2 Syracuse SR

Fully refundableReserve now, pay when you stay

CA $214

CA $244 total

Sep 2 - Sep 3

includes taxes & fees

Book a stay at this beach hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property condition ...

8.6/10 Excellent! (971 reviews)

"The only good thing was that I was able to shorten stay to one night and leave this hotel..tired and old hotel with misleading listing photos…the “beach” I"

Reviewed on Aug 13, 2026

Palazzo Artemide - VRetreats, SLH Collection

Via Roma 66 Syracuse SR

Fully refundableReserve now, pay when you stay

CA $343

CA $393 total

Aug 31 - Sep 1

includes taxes & fees

Stay at this hotel in Syracuse. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...

9.4/10 Exceptional! (684 reviews)

"Incredible place and location. Favorite time and place in Sicily."

Reviewed on Aug 21, 2026

Grande Albergo Alfeo

Via Nino Bixio 5 Syracuse SR

CA $128

CA $146 total

Sep 12 - Sep 13

includes taxes & fees

Book a stay at this business-friendly hotel in Syracuse. Enjoy free breakfast, free WiFi, and room service. Popular attractions Syracuse Forum Ruins and Santa ...

Mercure Siracusa Prometeo

Viale Teracati 20 Syracuse SR

Fully refundableReserve now, pay when you stay

CA $234

CA $283 total

Sep 13 - Sep 14

includes taxes & fees

Book a stay at this spa hotel in Syracuse. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular ...

Residence Archimede

Traversa Renella Syracuse SR

Fully refundableReserve now, pay when you stay

CA $222

CA $252 total

Sep 13 - Sep 14

includes taxes & fees

Book a stay at this beach hotel in Syracuse. Enjoy free parking, an outdoor pool, and breakfast (surcharge). Popular attractions Fontane Bianche Beach and Fanusa ...

9/10 Wonderful! (24 reviews)

"Avemu passatu na bedda vacanza ô Residence Archimede e lu cunsigghiamu senza dubbi. Lu staff fu sempri gentili e dispunìbbili, e l’appartamentu era granni, cunfurtèvuli e pulitu. La piscina era perfetta pi rilassarisi doppu na jurnata di giru, e puru lu ristoranti ni piaciù assai. La pusizioni è ..."

Reviewed on Jun 30, 2026

Eureka Palace Hotel Spa

Strada Spinagallo 50 Syracuse SR

Fully refundableReserve now, pay when you stay

CA $144

CA $164 total

Sep 13 - Sep 14

includes taxes & fees

Book a stay at this spa hotel in Syracuse. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

8/10 Very good! (350 reviews)

"Its next to the horse racetrack and seemes like the site is from a byfone era intended for horse races and events. The hotel is newer, but doesnt make full use of the amentities, for example there is a lobby bar/cafe buts its all tidied away and never staffed. The worst part is this is an isolated ..."

Reviewed on Aug 3, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Syracuse

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Syracuse 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Syracuse will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Syracuse, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.