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Featured Brookline 5 Star hotels

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

5 out of 5
450 Summer Street Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $191 per night from Jan 5 to Jan 6
CA $191
CA $278 total
Jan 5 - Jan 6
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,342 reviews)
Breakfast was very nice and lovely service. Room was exceptionally clean and temp was great.

Reviewed on Dec 28, 2025

Opens in a new windowOmni Boston Hotel at the Seaport
Encore Boston Harbor

Encore Boston Harbor

5 out of 5
1 Broadway Everett MA
Fully refundableReserve now, pay when you stay
The price is CA $311 per night from Jan 25 to Jan 26
CA $311
CA $348 total
Jan 25 - Jan 26
includes taxes & fees
Book a stay at this luxury hotel in Everett. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean rooms in ...
9.6/10 Exceptional! (3,496 reviews)
Room was beautiful, staff was very attentive and friendly , restaurants were great and spa was exceptional!

Reviewed on Dec 30, 2025

Opens in a new windowEncore Boston Harbor
The Langham, Boston

The Langham, Boston

5 out of 5
250 Franklin St Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $542 per night from Jan 18 to Jan 19
CA $542
CA $631 total
Jan 18 - Jan 19
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,002 reviews)
Clean room. Fantastic restaurant. Best bartender in town. Staff was professional and eager to assist with any needs or wants. Couldn’t have been a better stay unless it was free!

Reviewed on Jan 1, 2026

Opens in a new windowThe Langham, Boston
The Newbury Boston

The Newbury Boston

5 out of 5
15 Arlington St Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $554 per night from Jan 5 to Jan 6
CA $554
CA $718 total
Jan 5 - Jan 6
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful staff ...
9.2/10 Wonderful! (554 reviews)
Friendliness staffs, location, and amenities.

Reviewed on Dec 27, 2025

Opens in a new windowThe Newbury Boston
Four Seasons Hotel Boston

Four Seasons Hotel Boston

5 out of 5
200 Boylston St Boston MA
The price is CA $988 per night from Jan 9 to Jan 10
CA $988
CA $1,150 total
Jan 9 - Jan 10
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the room service ...
9.2/10 Wonderful! (454 reviews)
Very classic hotel and nice food in the restaurant

Reviewed on Dec 11, 2025

Opens in a new windowFour Seasons Hotel Boston
InterContinental Boston by IHG

InterContinental Boston by IHG

5 out of 5
510 Atlantic Ave Boston MA
Fully refundable
The price is CA $236 per night from Jan 4 to Jan 5
CA $236
CA $337 total
Jan 4 - Jan 5
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy a full-service spa, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,018 reviews)
Room was super clean and the staff was superb

Reviewed on Dec 28, 2025

Opens in a new windowInterContinental Boston by IHG
Boston Harbor Hotel

Boston Harbor Hotel

5 out of 5
70 Rowes Wharf Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $596 per night from Feb 1 to Feb 2
CA $596
CA $695 total
Feb 1 - Feb 2
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the helpful staff and the room service in ...
9.6/10 Exceptional! (1,013 reviews)
awesome hotel awesome service

Reviewed on Dec 29, 2025

Opens in a new windowBoston Harbor Hotel
Mandarin Oriental, Boston

Mandarin Oriental, Boston

5 out of 5
776 Boylston St Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $653 per night from Jan 14 to Jan 15
CA $653
CA $760 total
Jan 14 - Jan 15
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy a full-service spa, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (388 reviews)
Hotel and room were perfectly clean; staff were competent, friendly, and efficient. The bathroom for a double-occupancy room in a 5-star hotel should have 2 sinks; this one didn't.

Reviewed on Dec 24, 2025

Opens in a new windowMandarin Oriental, Boston
Four Seasons Hotel One Dalton Street, Boston

Four Seasons Hotel One Dalton Street, Boston

5 out of 5
One Dalton Street Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $713 per night from Jan 18 to Jan 19
CA $713
CA $831 total
Jan 18 - Jan 19
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (374 reviews)
Great place too stay

Reviewed on Dec 20, 2025

Opens in a new windowFour Seasons Hotel One Dalton Street, Boston
The Liberty, a Marriott Luxury Collection Hotel, Boston

The Liberty, a Marriott Luxury Collection Hotel, Boston

5 out of 5
215 Charles St Boston MA
Fully refundableReserve now, pay when you stay
The price is CA $259 per night from Jan 18 to Jan 19
CA $259
CA $342 total
Jan 18 - Jan 19
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy free WiFi, 2 restaurants, and 4 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (1,004 reviews)
The lobby/ bar area is amazing with Christmas Trees decorated and hanging upside down from 5+ story ceiling. Room was clean and beautiful, but thin walls - could hear coughing next food off and on all night (that was only negative of the hotel). Staff was very helpful.

Reviewed on Dec 26, 2025

Opens in a new windowThe Liberty, a Marriott Luxury Collection Hotel, Boston
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Five Star Hotels in Brookline

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Brookline to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Brookline 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Brookline before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Brookline hotel reviews by fellow wanderers