Find and compare 5 Star hotels in Brookline
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Featured Brookline 5 Star hotels

Omni Boston Hotel at the Seaport
This hotel is clean, the staff are friendly - just a great experience every time I stay here.
Reviewed on Apr 2, 2026

Encore Boston Harbor
Perfect hotel
Reviewed on Apr 3, 2026

The Langham, Boston
Very nice hotel
Reviewed on Mar 30, 2026

InterContinental Boston by IHG
Everything was perfect couldn’t have asked for a better room or service.
Reviewed on Apr 3, 2026

The Newbury Boston
Lovely lovely staff and accommodation.
Reviewed on Mar 31, 2026

Boston Harbor Hotel
Clean room, friendly staff, great amenities
Reviewed on Apr 3, 2026

The Liberty, a Marriott Luxury Collection Hotel, Boston
Great places, one of the front desk people are not friendly. Need new staff
Reviewed on Apr 3, 2026

Four Seasons Hotel One Dalton Street, Boston
wonderful stay
Reviewed on Mar 16, 2026

Mandarin Oriental, Boston
Beautiful hotel. From the moment you are greeted by the valet, bell hop, front reception you are treated like royalty. 5 stars all around!
Reviewed on Mar 16, 2026

Four Seasons Hotel Boston
Perfect in every way
Reviewed on Apr 2, 2026
Five Star Hotels in Brookline
Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Brookline to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Brookline 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Brookline before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Brookline hotel reviews by fellow wanderers

Encore Boston Harbor
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