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Featured Syracuse 5 Star hotels
Grand Hotel Ortigia Siracusa
"We stayed here for two nights and were extremely disappointed, especially considering this is supposed to be a five star property. Our first night we were put in a room where the bathroom had a horrid smell that spread to the entire room. The room was also on the same floor as all the cleaning staff ..."
Reviewed on May 17, 2026
Ortea Palace Hotel, Sicily, Autograph Collection
"The in-room WiFi wasn’t working and they said it wouldn’t be working. That the in-room was a third party and they had no control!! Out coffee table was about to fall apart. Maintenance did come to try and save it but they couldn’t. So we had to live with it for the duration of our stay. The bar was ..."
Reviewed on May 6, 2026
Caportigia Boutique Hotel
Dimora Caiammari Luxury Hotel & Spa
"room clean, staff is good, easy free parking"
Reviewed on May 5, 2026
Grand Hotel Des Ètrangers - The Leading Hotels of the World
"We were a bit disappointed with our stay at Grand Hotel des Étrangers. While the hotel has been beautifully renovated and is in very good condition, it felt more like a generic luxury hotel and lacked the Sicilian character we were hoping for. The breakfast room also felt somewhat “hotel-like,” although ..."
Reviewed on May 23, 2026
Minareto
"Beyond the hotel’s stunning and breathtaking views, the customer service was truly exceptional—both attentive and highly responsive. I would easily rate them 120%! I absolutely loved the jacuzzi and its location, which made the experience even more special. Both of the rocky and sandy beaches were ..."
Reviewed on Apr 22, 2026
Wellness & Spa Hotel Principe di Fitalia
"This was such a wonderful stay! Spotless beautiful property with friendly staff and delicious breakfast!!! Very impressed!"
Reviewed on Oct 19, 2025
Five Star Hotels in Syracuse
Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Syracuse to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Syracuse 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Syracuse before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Syracuse hotel reviews by fellow wanderers
Algila' Ortigia Charme Hotel
"Beautiful hotel in an excellent location. The breakfast was wonderful and the staff was very courteous and attentive. We loved the town of Ortigia."
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