Book a hotel near Fort Defiance State Park, Cairo
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Hotels near Fort Defiance State Park

Quality Inn Cairo I-57
13201 Kessler Road Cairo IL
Free cancellation
7.79 km from Fort Defiance State Park
The price is CA $100 per night
CA $100
CA $111 total
Dec 4 - Dec 5
includes taxes & fees
Stay at this hotel in Cairo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Fort Defiance State Park and Ballard Wildlife Management Area are located nearby.
Breakfast included
Pet-friendly

Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
Free cancellation
Reserve now, pay when you stay
17.52 km from Fort Defiance State Park
The price is CA $84 per night
CA $84
CA $94 total
Dec 1 - Dec 2
includes taxes & fees
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
Breakfast included
Pet-friendly

The Riverstone Hotel Charleston-Sikeston
102 Drake St Charleston MO
Free cancellation
20.22 km from Fort Defiance State Park
The price is CA $95 per night
CA $95
CA $106 total
Nov 18 - Nov 19
includes taxes & fees
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our reviews.
Pool
Breakfast included

Peaceful secluded cabin located near Horseshoe Lake
Miller City IL
21.13 km from Fort Defiance State Park
The price is CA $180 per night
CA $180
CA $274 total
Nov 16 - Nov 17
includes taxes & fees
Stay at this cabin in Alexander County. Enjoy patios, an in-room coffeemaker, and air conditioning.
Kitchen
Pet-friendly

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Kevil KY
26.1 km from Fort Defiance State Park
Stay at this vacation home in Kevil. Enjoy free breakfast, free WiFi, and a garden.
Breakfast included
Kitchen

Cozy cabins on beautiful Horseshoe Lake
Olive Branch IL
27.59 km from Fort Defiance State Park
The price is CA $161 per night
CA $161
CA $176 total
Nov 16 - Nov 17
includes taxes & fees
Stay at this cabin in Alexander County. Enjoy patios, an in-room coffeemaker, and air conditioning.
Air conditioning
Lake view

Wandering the wineries or hitting the hills? We got you! Come stay!
Tamms IL
31.33 km from Fort Defiance State Park
Book a stay at this family-friendly vacation home in Tamms. Enjoy a garden, laundry facilities, and a pool table.
Kitchen
Washer

Cozy cabin with pond
Paducah KY
32.8 km from Fort Defiance State Park
Stay at this cabin in Paducah. Enjoy patios and air conditioning. Popular attractions Paul Rowton Indoor Tennis Center and Purple Toad Winery are located nearby.
Kitchen
Air conditioning

Farm stay on 30 acres in Paducah, Kentucky
Paducah KY
32.82 km from Fort Defiance State Park
Stay at this farm stay in Paducah. Enjoy laundry facilities, patios, and air conditioning. Popular attractions Paul Rowton Indoor Tennis Center and Purple Toad Winery are located nearby.
Air conditioning
Parking available

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Free cancellation
Reserve now, pay when you stay
35.94 km from Fort Defiance State Park
The price is CA $100 per night
CA $100
CA $114 total
Dec 14 - Dec 15
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Pool
Breakfast included

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Free cancellation
Reserve now, pay when you stay
35.97 km from Fort Defiance State Park
The price is CA $95 per night
CA $95
CA $108 total
Nov 18 - Nov 19
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Breakfast included
Pet-friendly

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free cancellation
Reserve now, pay when you stay
36.31 km from Fort Defiance State Park
The price is CA $134 per night
CA $134
CA $154 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Pool
Breakfast included
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See all available properties in Fort Defiance State Park
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About Fort Defiance State Park Hotels Near Attractions
Do you have a full travel itinerary while visiting Fort Defiance State Park? Don't waste your time commuting too far from Fort Defiance State Park area attractions.
Fort Defiance State Park hotels essential information
Accommodation | 212 hotels |
|---|---|
Lowest Price | CA $94 |
Highest Price | CA $274 |
Popular hotels | Quality Inn Cairo I-57, Super 8 by Wyndham Charleston/Sikeston East MO, The Riverstone Hotel Charleston-Sikeston, Peaceful secluded cabin located near Horseshoe Lake , Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286, Cozy cabins on beautiful Horseshoe Lake, Drury Inn & Suites Sikeston, MO, Days Inn and Suites by Wyndham Sikeston, Wandering the wineries or hitting the hills? We got you! Come stay!, Best Western Plus Sikeston I-55, Cozy cabin with pond, Farm stay on 30 acres in Paducah, Kentucky |
Recent Fort Defiance State Park hotel reviews by fellow wanderers

Quality Inn Cairo I-57
5 out of 5
Posted 11 hours ago
Travelocity Verified Review
"Secluded but in a cool sort of ghost town with old buildings and not a lot of people. The lady at the front desk was awesome because I checked in late at night without realizing there wasn’t anywhere to get food around and she hooked me up with soup and a sandwich to save the day. Dispensary a couple streets over and a historic but now deserted town to explore. Five stars."
A verified traveller stayed at Quality Inn Cairo I-57





