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Featured Antigua Guatemala 4 Star hotels

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
The price is CA $364 per night from Feb 25 to Feb 26
CA $364
CA $461 total
Feb 25 - Feb 26
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,046 reviews)
Gorgeous hotel, clean room, friendly, helpful staff fascinating museum.

Reviewed on Feb 22, 2026

Opens in a new windowHotel Museo Spa Casa Santo Domingo
Porta Hotel Antigua

Porta Hotel Antigua

4.5 out of 5
8va Calle Poniente No1 Antigua Guatemala Sacatepequez
The price is CA $242 per night from Mar 3 to Mar 4
CA $242
CA $309 total
Mar 3 - Mar 4
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,005 reviews)
Everything was great!

Reviewed on Feb 19, 2026

Opens in a new windowPorta Hotel Antigua
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is CA $218 per night from Mar 1 to Mar 2
CA $218
CA $310 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (1,003 reviews)
Staff amazing room perfect location great and hotel a dream

Reviewed on Feb 23, 2026

Opens in a new windowHotel Camino Real Antigua
El Convento Boutique Hotel

El Convento Boutique Hotel

4 out of 5
2a Avenida Norte No. 11 Antigua Guatemala Sacatepequez
The price is CA $369 per night from Mar 9 to Mar 10
CA $369
CA $471 total
Mar 9 - Mar 10
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (838 reviews)
Staff were really friendly, amazing breakfast and excellent peaceful location. Importantly could still get into the centre of town so there was no compromise on location

Reviewed on Feb 15, 2026

Opens in a new windowEl Convento Boutique Hotel
Hotel Soleil La Antigua

Hotel Soleil La Antigua

4 out of 5
9 Calle Poniente Antigua Guatemala Sacatepequez
Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the property ...
8.8/10 Excellent! (1,001 reviews)
It was all good

Reviewed on Feb 23, 2026

Opens in a new windowHotel Soleil La Antigua
Hotel Casa Carmina

Hotel Casa Carmina

4 out of 5
9a Calle Poniente No. 17 Antigua Guatemala Sacatepéquez
The price is CA $211 per night from Mar 7 to Mar 8
CA $211
CA $260 total
Mar 7 - Mar 8
includes taxes & fees
Book a stay at this business-friendly hotel in Antigua Guatemala. Enjoy breakfast (surcharge), room service, and onsite spa services. Popular attractions Central ...
8.8/10 Excellent! (235 reviews)
Is ok

Reviewed on Feb 23, 2026

Opens in a new windowHotel Casa Carmina
Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa

4.5 out of 5
9 Calle Oriente No. 19 Antigua Guatemala Sacatepequez
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
9.4/10 Exceptional! (1,001 reviews)
Beautiful boutique hotel. This property is a little charming gem that is close to everything Antigua has to offer, yet situated in a quiet location. The property is meticulously maintained. There are beautiful interior gardens and terraces. Recommended for discerning clientele. The entire staff was ...

Reviewed on Feb 7, 2026

Opens in a new windowLos Pasos Boutique Hotel & Spa
Good Hotel Antigua

Good Hotel Antigua

4 out of 5
Calle del Hermano Pedro No. 12 Antigua Guatemala Sacatepéeuez
Fully refundableReserve now, pay when you stay
The price is CA $243 per night from Mar 16 to Mar 17
CA $243
CA $296 total
Mar 16 - Mar 17
includes taxes & fees
Stay at this hotel in Antigua Guatemala. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (538 reviews)
Great

Reviewed on Feb 23, 2026

Opens in a new windowGood Hotel Antigua
San Rafael Hotel

San Rafael Hotel

4 out of 5
2da calle Poniente No.7 Antigua Antigua Guatemala Sacatepequez
The price is CA $244 per night from Mar 9 to Mar 10
CA $244
CA $312 total
Mar 9 - Mar 10
includes taxes & fees
Book a stay at this boutique hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff and the ...
9.8/10 Exceptional! (451 reviews)
Great location. The property is pristine and beautiful, clean, comfortable.

Reviewed on Feb 24, 2026

Opens in a new windowSan Rafael Hotel
Hotel Casa Rustica

Hotel Casa Rustica

4 out of 5
6th Ave Norte 8 Antigua Guatemala Sacatepequez
The price is CA $164 per night from Mar 14 to Mar 15
CA $164
CA $200 total
Mar 14 - Mar 15
includes taxes & fees
Book a stay at this family-friendly hotel in Antigua Guatemala. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful ...
8.4/10 Very Good! (435 reviews)
Great location

Reviewed on Feb 21, 2026

Opens in a new windowHotel Casa Rustica
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4 Star Hotels Antigua Guatemala

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Antigua Guatemala 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Antigua Guatemala will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Antigua Guatemala, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Antigua Guatemala hotel reviews by fellow wanderers