Find and compare 4 Star hotels in Antigua Guatemala

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Featured Antigua Guatemala 4 Star hotels

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 out of 5
3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
The price is CA $367 per night from Jan 11 to Jan 12
CA $367
CA $465 total
Jan 11 - Jan 12
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,021 reviews)
Excellent

Reviewed on Jan 1, 2026

Opens in a new windowHotel Museo Spa Casa Santo Domingo
Porta Hotel Antigua

Porta Hotel Antigua

4.5 out of 5
8va Calle Poniente No1 Antigua Guatemala Sacatepequez
The price is CA $244 per night from Jan 14 to Jan 15
CA $244
CA $312 total
Jan 14 - Jan 15
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,009 reviews)
Room was great and staff was lovely

Reviewed on Jan 2, 2026

Opens in a new windowPorta Hotel Antigua
Hotel Camino Real Antigua

Hotel Camino Real Antigua

4 out of 5
7a Calle Poniente 33B Antigua Guatemala Sacatepequez
The price is CA $241 per night from Jan 20 to Jan 21
CA $241
CA $338 total
Jan 20 - Jan 21
includes taxes & fees
Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property ...
9.6/10 Exceptional! (1,002 reviews)
Hotel is beautiful. Staff is professional and friendly and the food at the restaurant is great!

Reviewed on Dec 31, 2025

Opens in a new windowHotel Camino Real Antigua
El Convento Boutique Hotel

El Convento Boutique Hotel

4 out of 5
2a Avenida Norte No. 11 Antigua Guatemala Sacatepequez
The price is CA $304 per night from Jan 12 to Jan 13
CA $304
CA $392 total
Jan 12 - Jan 13
includes taxes & fees
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (814 reviews)
Extremely

Reviewed on Jan 2, 2026

Opens in a new windowEl Convento Boutique Hotel
Hotel Soleil La Antigua

Hotel Soleil La Antigua

4 out of 5
9 Calle Poniente Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
Book a stay at this spa hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the property ...
8.6/10 Excellent! (1,008 reviews)
Great place to stay

Reviewed on Jan 2, 2026

Opens in a new windowHotel Soleil La Antigua
Hotel Casa Carmina

Hotel Casa Carmina

4 out of 5
9a Calle Poniente No. 17 Antigua Guatemala Sacatepéquez
The price is CA $118 per night from Jan 21 to Jan 22
CA $118
CA $144 total
Jan 21 - Jan 22
includes taxes & fees
Book a stay at this business-friendly hotel in Antigua Guatemala. Enjoy breakfast (surcharge), room service, and onsite spa services. Popular attractions Central ...
8.8/10 Excellent! (219 reviews)
Perfect. I wish they can have the breakfast included. Any way this hotel is 5 stars.

Reviewed on Dec 30, 2025

Opens in a new windowHotel Casa Carmina
Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa

4.5 out of 5
9 Calle Oriente No. 19 Antigua Guatemala Sacatepequez
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the property ...
9.2/10 Wonderful! (1,008 reviews)
The location was great for exploring the city on foot, and it was nice to have a restaurant on site with a wide variety of drink and food options. However, bells were set off every morning at 6:00, 6:30, and 7:00 - we were not prepared for this, and had difficulty sleeping. The staff were somewhat ...

Reviewed on Jan 2, 2026

Opens in a new windowLos Pasos Boutique Hotel & Spa
Good Hotel Antigua

Good Hotel Antigua

4 out of 5
Calle del Hermano Pedro No. 12 Antigua Guatemala Sacatepéeuez
Fully refundableReserve now, pay when you stay
The price is CA $285 per night from Jan 11 to Jan 12
CA $285
CA $348 total
Jan 11 - Jan 12
includes taxes & fees
Stay at this hotel in Antigua Guatemala. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (532 reviews)
Beautiful room, great location

Reviewed on Dec 31, 2025

Opens in a new windowGood Hotel Antigua
San Rafael Hotel

San Rafael Hotel

4 out of 5
2da calle Poniente No.7 Antigua Antigua Guatemala Sacatepequez
The price is CA $241 per night from Feb 2 to Feb 3
CA $241
CA $309 total
Feb 2 - Feb 3
includes taxes & fees
Book a stay at this boutique hotel in Antigua Guatemala. Enjoy free breakfast, free WiFi, and 24-hour room service. Our guests praise the helpful staff and the ...
9.8/10 Exceptional! (441 reviews)
This is such a gorgeous hotel - every aspect of our stay was beautifully appointed (rooms, courtyard, breakfast areas) and the staff were just lovely. It’s also super centrally located close & walkable to the major sites and, but you don’t step out into anything touristy. The breakfast was spectacular ...

Reviewed on Dec 26, 2025

Opens in a new windowSan Rafael Hotel
Hotel Casa Rustica

Hotel Casa Rustica

4 out of 5
6th Ave Norte 8 Antigua Guatemala Sacatepequez
Book a stay at this family-friendly hotel in Antigua Guatemala. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful ...
8.2/10 Very Good! (419 reviews)
Clean room

Reviewed on Dec 31, 2025

Opens in a new windowHotel Casa Rustica
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Antigua Guatemala

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Antigua Guatemala 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Antigua Guatemala will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Antigua Guatemala, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.