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Featured Greenville 4 Star hotels

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $384 per night from May 25 to May 26
CA $384
CA $434 total
May 25 - May 26
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.6/10 Exceptional! (492 reviews)
"Great setting, great service, beautiful rooms and wonderful restaurants"

Reviewed on May 15, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $233 per night from Jun 1 to Jun 2
CA $233
CA $303 total
Jun 1 - Jun 2
includes taxes & fees
Book a stay at this spa hotel in Greenville. Enjoy free parking, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (721 reviews)
"We loved the property! Lush, green hiking trails with ponds and a farm, right behind the hotel. The hotel staff were all very friendly and helpful. The hotel was meticulously maintained. One evening, I witnessed a hotel employee doing an inspection of the pool and even ran his hand over every Adirondack ..."

Reviewed on May 18, 2026

Opens in a new windowHotel Hartness
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

4 out of 5
101 Falls Park Dr Greenville SC
The price is CA $130 per night from Jun 1 to Jun 2
CA $130
CA $143 total
Jun 1 - Jun 2
includes taxes & fees
Stay at this apartment in Greenville. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (829 reviews)
"The ad for this property undersold what we got. This was a large apartment with a full kitchen, huge bathroom and separate laundry room. We were not expecting how nice it was. Great location, only a block of the river. Great food options. Downtown a very short walk. Riverwalk one block away. This ..."

Reviewed on May 18, 2026

Opens in a new windowMint House Greenville Downtown by Kasa
Greenville Marriott

Greenville Marriott

4 out of 5
One Parkway E Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $176 per night from May 31 to Jun 1
CA $176
CA $200 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.6/10 Excellent! (652 reviews)
"Didn't enjoy the lack of amenities inside of room, did not enjoy having to pay for wifi."

Reviewed on May 5, 2026

Opens in a new windowGreenville Marriott
The Westin Poinsett Greenville

The Westin Poinsett Greenville

4 out of 5
120 South Main St Greenville SC
Fully refundableReserve now, pay when you stay
The price is CA $260 per night from Jun 14 to Jun 15
CA $260
CA $290 total
Jun 14 - Jun 15
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...
9.2/10 Wonderful! (1,001 reviews)
"Great hotel. Absolutely beautiful. Front desk service was excellent. The concierge very unpleasant. That’s the only down side of the place. Restaurants was great, and it’s close to everything. Rooms was very clean."

Reviewed on May 16, 2026

Opens in a new windowThe Westin Poinsett Greenville
Park Place Apartments by Landing

Park Place Apartments by Landing

4 out of 5
31 Victor St Greenville SC
Stay at this aparthotel in Greenville. Enjoy free parking, a 24-hour fitness center, and in-room washers/dryers. Popular attractions Haywood Mall and Swamp Rabbit ...
7.6/10 Good! (46 reviews)
"The facility is beautiful, but there is no visibility of staff. We had several mechanical issues with dishwasher, washing machine and the Internet. We were able to resolve the Internet issue. But the dishwasher was never fixed during the four nights we stayed and our clothes. Locked in the washer. ..."

Reviewed on Jan 14, 2026

Opens in a new windowPark Place Apartments by Landing
140 Catlin Circle

140 Catlin Circle

4 out of 5
140 Catlin Circle Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Falls Park on the Reedy and ...
Opens in a new window140 Catlin Circle
Randall St , 202/204

Randall St , 202/204

4 out of 5
202 Randall Street Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Falls Park on the Reedy and ...
Opens in a new windowRandall St , 202/204
34 Allen St

34 Allen St

4 out of 5
34 Allen Street Greenville SC
Book a stay at this family-friendly vacation home in Greenville. Enjoy free WiFi, free parking, and a garden. Popular attractions Haywood Mall and Lewis Plaza ...
Opens in a new window34 Allen St
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4 Star Hotels Greenville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Greenville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Greenville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Greenville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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