Find and compare 4 Star hotels in Guayaquil

Wander Wisely with exceptional service, 24/7 support

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Featured Guayaquil 4 Star hotels

Wyndham Guayaquil Puerto Santa Ana

Calle Numa Pompilio Llona S N, Ciudad del Rio - Puerto Santa Ana, Guayaquil, Guayas

Fully refundableReserve now, pay when you stay

CA $152

CA $171 total

Oct 5 - Oct 6

Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...

9.2/10 Wonderful! (1,008 reviews)

"Excellent service José at the bar was a wonderful so kindness."

Reviewed on Sep 22, 2025

Unipark by Oro Verde Hotels

Clemente Ballén 406, entre Chile y Chimborazo, Guayaquil, Guayas

Fully refundableReserve now, pay when you stay

CA $90

CA $102 total

Oct 26 - Oct 27

Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...

9/10 Wonderful! (1,004 reviews)

"I enjoyed much my staying in this hotel."

Reviewed on Sep 19, 2025

Hilton Colon Guayaquil

Av Francisco de Orellana Mz 111, Guayaquil

Fully refundableReserve now, pay when you stay

CA $135

CA $152 total

Oct 5 - Oct 6

Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...

8.6/10 Excellent! (767 reviews)

"Exelente todo bien por mi Ecuador"

Reviewed on Aug 31, 2025

Grand Hotel Guayaquil, an Ascend Collection Hotel

Boyaca 1615, Guayaquil, Guayas

Fully refundableReserve now, pay when you stay

CA $105

CA $118 total

Oct 10 - Oct 11

Stay at this 4-star family-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...

9/10 Wonderful! (952 reviews)

"The pool is lovely if you love cold water. You have to make sure you put correct number of people or they question you."

Reviewed on Sep 13, 2025

Ibis Styles El Malecon Guayaquil

Av Malecon Simon Bolivar, Guayaquil

Fully refundableReserve now, pay when you stay

CA $83

CA $93 total

Sep 27 - Sep 28

Stay at this 4-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...

9.4/10 Exceptional! (248 reviews)

"Excellent service, a wide variety at breakfast, and very clean rooms. A highly recommended stay at Ibis."

Reviewed on Sep 16, 2025

TRYP by Wyndham Guayaquil Airport

Av. Joaquín Orrantia y L. Benitez, Guayaquil, Guayas

Fully refundableReserve now, pay when you stay

CA $137

CA $154 total

Oct 3 - Oct 4

Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in ...

8.8/10 Excellent! (1,007 reviews)

"Covenient, many options for dinning on premises."

Reviewed on Sep 7, 2025

Hotel Puerto Pacifico Guayaquil Airport

Av 33. Ciudadela La Garzota, Mz. 83 Solar 6-9, Guayaquil, Guayas

Fully refundableReserve now, pay when you stay

Stay at this 4-star family-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...

8.6/10 Excellent! (208 reviews)

"Loved my stay. It was very clean and close to the airport."

Reviewed on Sep 9, 2025

Get rates

Hotel Palace Guayaquil

Chile No # 214 y Luque, Guayaquil, Guayas

Fully refundableReserve now, pay when you stay

CA $87

CA $98 total

Sep 27 - Sep 28

Stay at this 4-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...

9/10 Wonderful! (900 reviews)

"Excellent"

Reviewed on Sep 7, 2025

Hotel del Parque

Parque Histórico de Guayaquil, Km 1.5, Samborondón, Av. Los Arcos y Río Guayas, Samborondon, Guayas

Fully refundableReserve now, pay when you stay

CA $594

CA $653 total

Oct 6 - Oct 7

Stay at this 4.5-star luxury hotel in Samborondon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Guayaquil Historic Park and Museum ...

9.6/10 Exceptional! (99 reviews)

"The staff when above and beyond. I would go back just because of the staff. I feel although the rooms are clean, very comfortable and spacious they need some TLC on maintenance like ceiling stain from prior leak."

Reviewed on Aug 31, 2025

Airbnb Urbanor

Avenida 27 no y calle 15 b no, Esquinera, Guayaquil, Guayas

Stay at this 4-star apartment in Guayaquil. Enjoy free WiFi, a 24-hour front desk, and dry cleaning or laundry services. Popular attractions City Mall and Guayaquil ...

Get rates

Don't see what you're looking for?

See all available properties in Guayaquil

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Guayaquil

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Guayaquil 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Guayaquil will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Guayaquil, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.