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Featured Guayaquil 4 Star hotels

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $136 per night from May 25 to May 26
CA $136
CA $153 total
May 25 - May 26
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,003 reviews)
"El hotel me encanta, pero me salieron esta vez con una tontería que no me hicieron bien mi reservación y me dieron otro tipo de habitación la primer noche de cuatro. Muy amables hicieron todo por mejorar el asunto, pero definitivamente es pésimo llegar cansado de viaje y que te salgan con una tontería ..."

Reviewed on May 18, 2026

Opens in a new windowWyndham Guayaquil Puerto Santa Ana
Unipark by Oro Verde Hotels

Unipark by Oro Verde Hotels

4 out of 5
Clemente Ballén 406 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $89 per night from May 22 to May 23
CA $89
CA $102 total
May 22 - May 23
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the comfy ...
9.2/10 Wonderful! (1,003 reviews)
"The room was clean and the view from the seventh floor was amazing facing the park and the cathedral. The buffet breakfast was hearty and with a good variety of local and general cuisine. The staff was very helpful and courteous. It was easy to reserve taxis directly from the hotel and the airport ..."

Reviewed on May 16, 2026

Opens in a new windowUnipark by Oro Verde Hotels
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
Fully refundableReserve now, pay when you stay
The price is CA $130 per night from Jun 13 to Jun 14
CA $130
CA $146 total
Jun 13 - Jun 14
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (912 reviews)
"It was perfect the staff was bilingual...came for my niece's 13th birthday....it was unbelievable."

Reviewed on May 17, 2026

Opens in a new windowHilton Colon Guayaquil
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 out of 5
Av. Joaquín Orrantia y L. Benitez Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $118 per night from May 25 to May 26
CA $118
CA $133 total
May 25 - May 26
Book a stay at this luxury hotel in Guayaquil. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in our ...
9/10 Wonderful! (1,001 reviews)
"Recomendado"

Reviewed on May 15, 2026

Opens in a new windowTRYP by Wyndham Guayaquil Airport
Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel

4 out of 5
Boyaca 1615 Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $97 per night from May 29 to May 30
CA $97
CA $109 total
May 29 - May 30
Book a stay at this family-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
Opens in a new windowGrand Hotel Guayaquil, an Ascend Collection Hotel
Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport

4 out of 5
Av 33. Ciudadela La Garzota Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $74 per night from May 22 to May 23
CA $74
CA $76 total
May 22 - May 23
Book a stay at this family-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (255 reviews)
"Buen desayuno"

Reviewed on Apr 27, 2026

Opens in a new windowHotel Puerto Pacifico Guayaquil Airport
Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil

4 out of 5
Av Malecon Simon Bolivar Guayaquil
Fully refundableReserve now, pay when you stay
The price is CA $58 per night from Jun 5 to Jun 6
CA $58
CA $66 total
Jun 5 - Jun 6
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (307 reviews)
"Clean room"

Reviewed on May 10, 2026

Opens in a new windowIbis Styles El Malecon Guayaquil
Hotel Palace Guayaquil

Hotel Palace Guayaquil

4 out of 5
Chile No # 214 y Luque Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is CA $79 per night from May 23 to May 24
CA $79
CA $89 total
May 23 - May 24
Book a stay at this business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (933 reviews)
"Ubicación"

Reviewed on May 11, 2026

Opens in a new windowHotel Palace Guayaquil
Hotel del Parque

Hotel del Parque

4.5 out of 5
Parque Histórico de Guayaquil, Km 1.5 Samborondon Guayas
Fully refundableReserve now, pay when you stay
The price is CA $590 per night from May 23 to May 24
CA $590
CA $649 total
May 23 - May 24
Book a stay at this luxury hotel in Samborondon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Guayaquil Historic Park and Museum of ...
9.8/10 Exceptional! (114 reviews)
"Amazing place! Great food at the restaurant and great drinks as well!!"

Reviewed on May 12, 2026

Opens in a new windowHotel del Parque
Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil

4.5 out of 5
Av. Dr. Camilo Nevárez Vásquez Guayaquil Guayas
The price is CA $36 per night from Jun 1 to Jun 2
CA $36
CA $44 total
Jun 1 - Jun 2
Book a stay at this luxury aparthotel in Guayaquil. Enjoy free WiFi, free valet parking, and a 24-hour front desk. Popular attractions Mall del Sol Shopping ...
9.2/10 Wonderful! (12 reviews)
"Well equipped suite. Walking distance to airport"

Reviewed on Feb 11, 2026

Opens in a new windowSuitesecu Rentals Guayaquil
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4 Star Hotels Guayaquil

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Guayaquil 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Guayaquil will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Guayaquil, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Guayaquil hotel reviews by fellow wanderers