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Featured Hyannis 4 Star hotels

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

4 out of 5
1225 Iyannough Rd Hyannis MA
Fully refundableReserve now, pay when you stay
The price is CA $359 per night from Jun 17 to Jun 18
CA $359
CA $491 total
Jun 17 - Jun 18
includes taxes & fees
Book a stay at this spa resort in Hyannis. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the clean rooms in our reviews. Popular attractions ...
8.8/10 Excellent! (595 reviews)
"Everything was clean and well taken care of. My only suggestion as a mom traveling alone with a 7, 6 and 4 year old is having bathroom areas directly at pool/water park areas and maybe some wash off stations. Every time one of the kids had to use the bathroom, we all have to get out, get our stuff, ..."

Reviewed on Jun 13, 2026

Opens in a new windowMargaritaville Resort Cape Cod
The Mansion at Ocean Edge

The Mansion at Ocean Edge

4 out of 5
2907 Main Street Brewster MA
The price is CA $520 per night from Jun 16 to Jun 17
CA $520
CA $676 total
Jun 16 - Jun 17
includes taxes & fees
Book a stay at this luxury hotel in Brewster. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very Good! (1,005 reviews)
"A beautiful place!"

Reviewed on Jun 13, 2026

Opens in a new windowThe Mansion at Ocean Edge
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

4 out of 5
135 Route 28 West Yarmouth MA
Fully refundableReserve now, pay when you stay
The price is CA $252 per night from Jun 16 to Jun 17
CA $252
CA $299 total
Jun 16 - Jun 17
includes taxes & fees
Book a stay at this beach hotel in West Yarmouth. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. ...
9.4/10 Exceptional! (165 reviews)
"This is really a motel that's been renovated. I stayed one night. Check-in wasn't quick as they wanted to collect my email and phone number, though all that info should have been available via my booking. The room is nice enough - a little dark because the only lighting is via the slider door, which ..."

Reviewed on Jun 13, 2026

Opens in a new windowUncommoner Hotel by Reverie Boutique Collection
AutoCamp Cape Cod

AutoCamp Cape Cod

4 out of 5
836 Palmer Avenue Falmouth MA
The price is CA $208 per night from Jun 17 to Jun 18
CA $208
CA $295 total
Jun 17 - Jun 18
includes taxes & fees
Stay at this holiday park in Falmouth. Enjoy free WiFi, free parking, and free bicycles on site. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (338 reviews)
"It's beautiful and the airstreams were beautiful, would have been great if they had a pool onsite, not much here for kids,but we enjoyed"

Reviewed on Jun 14, 2026

Opens in a new windowAutoCamp Cape Cod
Chatham Wayside Inn

Chatham Wayside Inn

4 out of 5
512 Main St Chatham MA
The price is CA $625 per night from Jun 17 to Jun 18
CA $625
CA $776 total
Jun 17 - Jun 18
includes taxes & fees
Book a stay at this golf hotel in Chatham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our ...
9.2/10 Wonderful! (690 reviews)
"Chatham is beautiful and the Wayside Inn is so charming. We had a garden king room very spacious, clean, comfy king bed, huge accessible bathroom, fridge, safe, ironing facilities beautiful little garden with table and chairs. Continental breakfast cereal, fruit, bagels muffins, boiled and scrambled ..."

Reviewed on Jun 10, 2026

Opens in a new windowChatham Wayside Inn
Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis

4 out of 5
287 Iyannough Rd Hyannis MA
Fully refundableReserve now, pay when you stay
The price is CA $320 per night from Jun 21 to Jun 22
CA $320
CA $366 total
Jun 21 - Jun 22
includes taxes & fees
Stay at this hotel in Hyannis. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Main ...
8.4/10 Very Good! (910 reviews)
"Clean rooms. Comfy bed!"

Reviewed on Jun 14, 2026

Opens in a new windowDoubletree by Hilton Cape Cod - Hyannis
Queen Anne Inn

Queen Anne Inn

4 out of 5
70 Queen Anne Rd Chatham MA
Fully refundableReserve now, pay when you stay
The price is CA $384 per night from Jun 16 to Jun 17
CA $384
CA $439 total
Jun 16 - Jun 17
includes taxes & fees
Stay at this hotel in Chatham. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Veterans ...
8.8/10 Excellent! (239 reviews)
"It is an old property and very tired. Not very clean."

Reviewed on Jun 9, 2026

Opens in a new windowQueen Anne Inn
Starlight Lodge Cape Cod

Starlight Lodge Cape Cod

4 out of 5
203 Main St Dennis MA
Stay at this lodge in Dennis. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Mayflower Beach and The Club at Yarmouthport are located ...
8.2/10 Very Good! (26 reviews)
"Room was so cozy. We really liked it for an off season visit."

Reviewed on Dec 1, 2025

Opens in a new windowStarlight Lodge Cape Cod
Captain's House Inn

Captain's House Inn

4 out of 5
369 Old Harbor Road Chatham MA
Stay at this B&B in Chatham. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Chatham Shark Center and Chatham Seaside Links are located ...
9.8/10 Exceptional! (226 reviews)
"We really enjoyed the property. The bedding and pillows were heavenly! Our sitting room and bathroom could have used a bit of updating. We were in the Clarissa Suite. Overall, the property was lovely and the Staff were exceptional, kind and very helpful. We will definitely return. The Breakfast was ..."

Reviewed on Jun 2, 2026

Opens in a new windowCaptain's House Inn
Winstead Inn

Winstead Inn

4 out of 5
116 Parallel Harwich MA
Book a stay at this beach guesthouse in Harwich. Enjoy free breakfast, free parking, and an outdoor pool. Popular attractions Ocean Edge Golf Club and Cape Cod ...
9.4/10 Exceptional! (132 reviews)
"Loved this place. Private beach area in particular. Charming inn feel."

Reviewed on Jun 14, 2026

Opens in a new windowWinstead Inn
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4 Star Hotels Hyannis

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Hyannis 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Hyannis will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Hyannis, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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