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Featured Mestre 4 Star hotels

Hotel Plaza Venice

Hotel Plaza Venice

4 out of 5
Viale Stazione 36 Mestre VE
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,013 reviews)
Room was very clean..The staff very friendly and helpful..The location is amazing directly across from train station..Only 2 stops into Venice main station .

Reviewed on Feb 16, 2026

Opens in a new windowHotel Plaza Venice
Annia Park Hotel Venice Airport

Annia Park Hotel Venice Airport

4 out of 5
Via Triestina 161 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $246 per night from Feb 25 to Feb 26
CA $246
CA $281 total
Feb 25 - Feb 26
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...
9.2/10 Wonderful! (1,002 reviews)
The room was an ok spot to crash given the location to the airport but the room itself felt very stuff and a strange layout that felt kind of “harry potter cupboard” and stuffy.. it wasn’t what we expected based on the photos.

Reviewed on Feb 18, 2026

Opens in a new windowAnnia Park Hotel Venice Airport
Hotel Cavalletto e Doge Orseolo

Hotel Cavalletto e Doge Orseolo

4 out of 5
Piazza San Marco 1107 Venice VE
Fully refundable
The price is CA $173 per night from Mar 10 to Mar 11
CA $173
CA $205 total
Mar 10 - Mar 11
includes taxes & fees
Stay at this hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,710 reviews)
I really love this place lovely and kind people we have the best room with 2 balcony’s we had an early flight they even gave us breakfast to go :) highly recommended !!!

Reviewed on Feb 22, 2026

Opens in a new windowHotel Cavalletto e Doge Orseolo
Hotel Saturnia & International

Hotel Saturnia & International

4.5 out of 5
San Marco 2398 - Via XXII Marzo Venice VE
The price is CA $205 per night from Mar 10 to Mar 11
CA $205
CA $241 total
Mar 10 - Mar 11
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the bar in our reviews. ...
9.6/10 Exceptional! (1,003 reviews)
The room was just beauriful. View of the small rio below gave a great experience of life on the water. Hotel staff were very welcoming and so helpful. Bar atmosphere and staff also made for a very pleasant evening.

Reviewed on Feb 20, 2026

Opens in a new windowHotel Saturnia & International
Hotel Rialto

Hotel Rialto

4 out of 5
San Marco 5149 Ponte Di Rialto Venice VE
The price is CA $152 per night from Feb 25 to Feb 26
CA $152
CA $182 total
Feb 25 - Feb 26
includes taxes & fees
Stay at this hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,011 reviews)
We booked a Junior Suite, but the first room we were assigned was unacceptable. Opening the windows revealed nothing but a tiny, dark corner and a loud machine that ran all night, making sleep impossible. After a fight and an intervention from Expedia, we were moved the next day. The second room ...

Reviewed on Feb 22, 2026

Opens in a new windowHotel Rialto
Splendid Venice – Starhotels Collezione

Splendid Venice – Starhotels Collezione

4 out of 5
San Marco Mercerie 760 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $330 per night from Mar 2 to Mar 3
CA $330
CA $377 total
Mar 2 - Mar 3
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,008 reviews)
The hotel room was lovely-spacious, clean and luxurious. The staff incredible and the location ideal for exploring. Will book again for certain.

Reviewed on Feb 22, 2026

Opens in a new windowSplendid Venice – Starhotels Collezione
Best Western Plus Hotel Bologna

Best Western Plus Hotel Bologna

4 out of 5
Via Piave 214 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $180 per night from Feb 27 to Feb 28
CA $180
CA $208 total
Feb 27 - Feb 28
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the ...
9.4/10 Exceptional! (1,001 reviews)
Friendly welcome by the reception staff, and a spacious, quiet comfortable room.

Reviewed on Feb 10, 2026

Opens in a new windowBest Western Plus Hotel Bologna
Hotel Venice Resort Airport

Hotel Venice Resort Airport

4 out of 5
Via Triestina, 153 Mestre VE
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,003 reviews)
Beautiful room. friendly staff. great service. Great location just minutes to the airport. Also they helped us with a quick walk to a bus that took us to Venice! Would def recommend.

Reviewed on Feb 21, 2026

Opens in a new windowHotel Venice Resort Airport
H10 Palazzo Canova

H10 Palazzo Canova

4.5 out of 5
San Polo - Via Riva del Vin 744 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $293 per night from Mar 2 to Mar 3
CA $293
CA $337 total
Mar 2 - Mar 3
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.8/10 Exceptional! (1,005 reviews)
We had a fantastic stay at the hotel. The staff were always available to help out and our room was spacious and clean even though we didn’t have a view of the Grand Canal we thought it was excellent.

Reviewed on Feb 23, 2026

Opens in a new windowH10 Palazzo Canova
Palazzo Veneziano

Palazzo Veneziano

4.5 out of 5
Fondamenta delle Zattere 1413 Venice VE
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our ...
9.6/10 Exceptional! (1,161 reviews)
Great room, great location, a great bar with wide variety of Negroni's (if that's your thing!). Staff was friendly and easy to work with. Definitely recommend.

Reviewed on Feb 22, 2026

Opens in a new windowPalazzo Veneziano
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4 Star Hotels Mestre

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mestre 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mestre will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mestre, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mestre hotel reviews by fellow wanderers