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Featured Mestre 4 Star hotels

Hotel Cavalletto e Doge Orseolo

Hotel Cavalletto e Doge Orseolo

4 out of 5
Piazza San Marco 1107, Calle del Cavalletto, Venice, VE
Fully refundable
The price is CA $306 per night from Oct 13 to Oct 14
CA $306
CA $351 total
Oct 13 - Oct 14
includes taxes & fees
Stay at this 4-star hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the bar in our reviews. Popular attractions ...
8.6/10 Excellent! (1,694 reviews)
"Great breakfast, amazing location, staff very friendly!"

Reviewed on Sep 28, 2025

Opens in a new windowHotel Cavalletto e Doge Orseolo
Hotel Rialto

Hotel Rialto

4 out of 5
San Marco 5149 Ponte Di Rialto, Venice, VE
Fully refundableReserve now, pay when you stay
The price is CA $231 per night from Nov 2 to Nov 3
CA $231
CA $269 total
Nov 2 - Nov 3
includes taxes & fees
Stay at this 4-star hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,029 reviews)
"El hotel tiene muy buena ubicación, limpio, la atención al momento pero el jabón de ducha estaba vacío y me pareció que la limpieza solo fue cambiar las toallas y tender la cama. El jabón que estábamos utilizando todavía estaba en la jabonera"

Reviewed on Sep 28, 2025

Opens in a new windowHotel Rialto
Hotel Principe

Hotel Principe

4 out of 5
Rio Tera Lista de Spagna, 146, Venice, VE
Fully refundableReserve now, pay when you stay
The price is CA $406 per night from Oct 11 to Oct 12
CA $406
CA $462 total
Oct 11 - Oct 12
includes taxes & fees
Stay at this 4-star hotel in Venice. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.6/10 Excellent! (1,001 reviews)
Great location just 5 mins walk from the station
"Fabulous location, my room opened to the canal and that made it even more special. Rooms have very old style furnishings but that’s with most hotels in Venice. The room was very spacious and also had very high ceilings creating an added sense of space. Breakfast was just average"

Reviewed on Sep 24, 2025

Opens in a new windowHotel Principe
Hotel Plaza Venice

Hotel Plaza Venice

4 out of 5
Viale Stazione 36, Mestre, VE
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Mestre. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,019 reviews)
"Great, friendly staff. Very nicely appointed room, good breakfast, and great location across from the train station."

Reviewed on Sep 24, 2025

Opens in a new windowHotel Plaza Venice
Venezia Palazzo Barocci

Venezia Palazzo Barocci

4.5 out of 5
San Marco. Corte dell'Albero 3878/A, Venice, VE
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (827 reviews)
"Venice - spoilt for choice!"

Reviewed on Sep 28, 2025

Opens in a new windowVenezia Palazzo Barocci
Splendid Venice – Starhotels Collezione

Splendid Venice – Starhotels Collezione

4 out of 5
San Marco Mercerie 760, Venice, VE
Fully refundableReserve now, pay when you stay
The price is CA $342 per night from Nov 2 to Nov 3
CA $342
CA $391 total
Nov 2 - Nov 3
includes taxes & fees
Stay at this 4-star luxury hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,022 reviews)
"Clean pleasant hotel"

Reviewed on Sep 25, 2025

Opens in a new windowSplendid Venice – Starhotels Collezione
Annia Park Hotel Venice Airport

Annia Park Hotel Venice Airport

4 out of 5
Via Triestina 161, Tessera, Mestre, VE
Fully refundableReserve now, pay when you stay
The price is CA $250 per night from Nov 1 to Nov 2
CA $250
CA $285 total
Nov 1 - Nov 2
includes taxes & fees
Stay at this 4-star business-friendly hotel in Mestre. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (1,019 reviews)
"Great boutique hotel. Felt like family. Good food in restaurant and exceeded expectations. Wonderful breakfast buffet with fresh squeezed orange juice machine."

Reviewed on Sep 29, 2025

Opens in a new windowAnnia Park Hotel Venice Airport
Royal San Marco Hotel

Royal San Marco Hotel

4 out of 5
San Marco Calle dei Fabbri, Venice, VE
Fully refundableReserve now, pay when you stay
The price is CA $214 per night from Nov 2 to Nov 3
CA $214
CA $250 total
Nov 2 - Nov 3
includes taxes & fees
Stay at this 4-star hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
8/10 Very Good! (1,007 reviews)
Location, location, location!
"We had a wonderful 4 night stay at Royal San Marco Hotel. The room was very spacious and comfortable, but most importantly was the location! Right off of San Marco Square, it was centrally located to everything we wanted to do."

Reviewed on Sep 16, 2025

Opens in a new windowRoyal San Marco Hotel
Best Western Plus Hotel Bologna

Best Western Plus Hotel Bologna

4 out of 5
Via Piave 214, Mestre, VE
Fully refundableReserve now, pay when you stay
The price is CA $183 per night from Nov 2 to Nov 3
CA $183
CA $211 total
Nov 2 - Nov 3
includes taxes & fees
Stay at this 4-star business-friendly hotel in Mestre. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,019 reviews)
"Location of the property is awesome, right across the street from the Mestre train station. Restaurants are a very short walk away. Check-in was very fast and courteous. The room itself was outstanding - very roomy and well equipped. The bed was comfortable and we slept well. Not once did I hear ..."

Reviewed on Sep 28, 2025

Opens in a new windowBest Western Plus Hotel Bologna
H10 Palazzo Canova

H10 Palazzo Canova

4.5 out of 5
San Polo - Via Riva del Vin 744, Venice, VE
Fully refundableReserve now, pay when you stay
The price is CA $468 per night from Nov 2 to Nov 3
CA $468
CA $530 total
Nov 2 - Nov 3
includes taxes & fees
Stay at this 4.5-star luxury hotel in Venice. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful staff ...
9.6/10 Exceptional! (1,022 reviews)
"Amazing"

Reviewed on Sep 27, 2025

Opens in a new windowH10 Palazzo Canova
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4 Star Hotels Mestre

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mestre 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mestre will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mestre, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mestre hotel reviews by fellow wanderers