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Featured Mestre 4 Star hotels

Amadeus Hotel

Amadeus Hotel

4 out of 5
Lista di Spagna Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $210 per night from Jun 30 to Jul 1
CA $210
CA $246 total
Jun 30 - Jul 1
includes taxes & fees
Book a stay at this business-friendly hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very good! (1,000 reviews)
"More like a 2-stars hotel."

Reviewed on Jun 18, 2026

Opens in a new windowAmadeus Hotel
Hotel Plaza Venice

Hotel Plaza Venice

4 out of 5
Viale Stazione 36 Mestre VE
The price is CA $161 per night from Jun 30 to Jul 1
CA $161
CA $187 total
Jun 30 - Jul 1
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,007 reviews)
"Unforgettable experience staying at Residenza San Paolo VI. Stayed twice first with mom and then with family. Yocasta, Natalie and all at the front desk attended my family with details and support. Giulia provided an incredible breakfast experience with extra care in providing extra cappuccino’s. ..."

Reviewed on Jun 25, 2026

Opens in a new windowHotel Plaza Venice
Carnival Palace Hotel

Carnival Palace Hotel

4.5 out of 5
Fondamenta di Cannaregio, 929 Venice VE
The price is CA $250 per night from Jul 26 to Jul 27
CA $250
CA $290 total
Jul 26 - Jul 27
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,004 reviews)
"Convenient. Close to all major attractions with out the tourists."

Reviewed on Jun 24, 2026

Opens in a new windowCarnival Palace Hotel
Hotel Rialto

Hotel Rialto

4 out of 5
San Marco 5149 Ponte Di Rialto Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $212 per night from Jul 5 to Jul 6
CA $212
CA $248 total
Jul 5 - Jul 6
includes taxes & fees
Stay at this hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9/10 Wonderful! (1,024 reviews)
"This was my second time in 15 years but this time we had a back of the hotel view to a building so we didn't have the front of the hotel view. For that I was very disappointed"

Reviewed on Jun 26, 2026

Opens in a new windowHotel Rialto
Hotel Venice Resort Airport

Hotel Venice Resort Airport

4 out of 5
Via Triestina, 153 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $208 per night from Jun 30 to Jul 1
CA $208
CA $243 total
Jun 30 - Jul 1
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very good! (1,005 reviews)
"I (solo female in my 60’s) stayed in single room for 1 night at Hotel Venice Resort Airport and was happy with it. Used shuttle to get to airport (10 min ride) for early flight. Staff friendly and helpful. Room quiet and comfortable, had chair and small desk. Hotel very safe. I would definitely stay ..."

Reviewed on Jun 27, 2026

Opens in a new windowHotel Venice Resort Airport
Palazzo Veneziano

Palazzo Veneziano

4.5 out of 5
Fondamenta delle Zattere 1413 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $349 per night from Jul 29 to Jul 30
CA $349
CA $398 total
Jul 29 - Jul 30
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our ...
9.6/10 Exceptional! (1,163 reviews)
"We had a good stay overall and found the hotel to be clean, comfortable, and well maintained. The staff were friendly and helpful throughout our visit, and the room itself was pleasant. There were a few drawbacks that future guests may want to consider. The location was a bit farther from the main ..."

Reviewed on Jun 26, 2026

Opens in a new windowPalazzo Veneziano
Colombina Hotel

Colombina Hotel

4 out of 5
Castello, Calle Del Remedio 4416 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $301 per night from Jul 27 to Jul 28
CA $301
CA $346 total
Jul 27 - Jul 28
includes taxes & fees
Stay at this hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,001 reviews)
"The staff is unbelievable with helping with anything like transportation, booking restaurants, making recommendations. Everyone was so kind and the location is the best. Even though it is so close to St Marks, it is super quiet."

Reviewed on Jun 25, 2026

Opens in a new windowColombina Hotel
Hotel Cavalletto e Doge Orseolo

Hotel Cavalletto e Doge Orseolo

4 out of 5
Piazza San Marco 1107 Venice VE
Fully refundable
The price is CA $266 per night from Jul 27 to Jul 28
CA $266
CA $307 total
Jul 27 - Jul 28
includes taxes & fees
Stay at this hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,806 reviews)
"We were anxious about getting to Venice airport by 9:00 am. Hotel arranged pick up at the hotel for a water taxi to airport direct. Enjoyed the wild speedboat ride to the airport getting there in perfect time."

Reviewed on Jun 27, 2026

Opens in a new windowHotel Cavalletto e Doge Orseolo
Novotel Venezia Mestre Castellana

Novotel Venezia Mestre Castellana

4 out of 5
Via Alfredo Ceccherini 21 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $119 per night from Jul 13 to Jul 14
CA $119
CA $141 total
Jul 13 - Jul 14
includes taxes & fees
Book a stay at this family-friendly hotel in Mestre. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.4/10 Very good! (1,002 reviews)
"We stay there a lot as it's very convenient. It's close enough to Venice but close enough to she shops and Mestre centre and all nice restaurants."

Reviewed on Jun 23, 2026

Opens in a new windowNovotel Venezia Mestre Castellana
Santa Chiara Hotel

Santa Chiara Hotel

4.5 out of 5
Santa Croce 548 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $360 per night from Jul 21 to Jul 22
CA $360
CA $411 total
Jul 21 - Jul 22
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a rooftop terrace, and room service. Our guests praise the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (364 reviews)
"The he hotel was beautiful great location. We really enjoyed the coffee and breakfast. The staff was incredibly helpful."

Reviewed on Jun 27, 2026

Opens in a new windowSanta Chiara Hotel
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4 Star Hotels Mestre

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mestre 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mestre will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mestre, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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