Find and compare 4 Star hotels in Syracuse
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Featured Syracuse 4 Star hotels

Algila' Ortigia Charme Hotel
"Excellent, charming hotel. Lovely staff and beautiful rooms. We loved it."
Reviewed on Jul 8, 2026

Grande Albergo Alfeo
"We stayed here for a few nights and had a great experience from start to finish. The room was very clean, the staff was welcoming and helpful whenever we needed anything, and the breakfast had plenty of fresh options each morning. The air conditioning worked flawlessly, which made the room especially ..."
Reviewed on Jul 5, 2026

Eureka Palace Hotel Spa Resort
"The room was spacious, very clean, balcony was huge with a view over the front of the hotel. The staff were very friendly. Particularly the resteraunt staff. Veronica was very helpful with the menu and very courteous. The food was excellent both for breakfast & Dinner. A minor observation was that ..."
Reviewed on Jun 9, 2026

UNA Hotels One Siracusa Wellness & SPA
"Great room, breakfast, and staff. Adequate parking. Not too far from the historic district. Only issue we had is that the walls everywhere are painted black and lights were barely on, so it’s difficult to see where you are going. That’s the vibe, but older people like us may have a problem."
Reviewed on Mar 23, 2026

Palazzo Artemide - VRetreats, SLH Collection
"Nice hotel, great location and absolutely fantastic stuff!"
Reviewed on Jul 6, 2026

Hotel Parco delle Fontane

Mercure Siracusa Prometeo
"Wow, what a fantastic hotel. Super location for the Archeological Park & Museum. Rooms and amenities were great, the pool and sundeck perfect for a drink. Staff were friendly and helpful, breakfast was spectacular, everything you could want for a Sicilian breakfast. Rooms were modern and comfortable ..."
Reviewed on May 14, 2026

Hotel Villamare

Grand Hotel Villa Politi
"The rooms are really nice, smaller than pictures, but nice. View was ok, small porthole in a Concrete wall. Pool was great, breakfast was amazing. Staff are very friendly and attentive. We had a car so it was 7 minute drive to parking outside Ortigia every evening plus we did day trips to Noto, Catania, ..."
Reviewed on Jun 29, 2026

Charme Hotel Henry's House
"We had such an amazing stay! The location is absolutely perfect right on the sea, and the location for breakfast is absolutely stunning. The breakfast is delicious and the coffee is amazing. All the staff are so friendly and made our stay very personable and memorable. I hope to come back it is the ..."
Reviewed on Jun 25, 2026
4 Star Hotels Syracuse
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Syracuse 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Syracuse will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Syracuse, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Syracuse hotel reviews by fellow wanderers

Algila' Ortigia Charme Hotel
"Excellent, charming hotel. Lovely staff and beautiful rooms. We loved it."
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