Adults Only Resorts & Hotels in South Carolina from CA $85

Wander Wisely with exceptional service, 24/7 support

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top South Carolina Adults Only Resorts & Hotels

86 Cannon Charleston - Adults Only

86 Cannon Street Charleston SC

CA $846

CA $964 total

Sep 29 - Sep 30

includes taxes & fees

Book a stay at this luxury guesthouse in Charleston. Enjoy free breakfast, free WiFi, and free bicycles on site. Popular attractions Charleston City Market and South Carolina Aquarium are located nearby.

Affordable Suites Myrtle Beach

117 W Perry Rd. Myrtle Beach SC

Get rates

Stay at this hotel in Myrtle Beach. Enjoy free WiFi, free parking, and laundry facilities. Popular attractions Broadway at the Beach and Coastal Grand Mall are located nearby.

Baymont by Wyndham Orangeburg North

3583 Saint Matthews Rd Orangeburg SC

Free cancellation

Reserve now, pay when you stay

CA $77

CA $85 total

Sep 23 - Sep 24

includes taxes & fees

Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium are located nearby.

Beach Lover's Condo With Spectacular Ocean View, Pool, Lazy River, & Jacuzzi!

North Myrtle Beach SC

Get rates

Book a stay at this beach condo in North Myrtle Beach. Enjoy free WiFi, a beach locale, and a garden. Popular attractions House of Blues Myrtle Beach and Barefoot Landing are located nearby.

Detached Guest Suite

Charleston SC

Get rates

Book a stay at this golf cottage in Charleston. Enjoy free WiFi, a garden, and laundry facilities. Our guests praise the pool and the helpful staff in our reviews. Popular attractions North Charleston Coliseum and Charleston Tanger Outlets are located nearby.

Downtown-One-of-a-Kind Romantic Luxury Residence 5BR, 3BA Sleeps 10 to 12

Charleston SC

CA $866

CA $1,353 total

Aug 30 - Aug 31

includes taxes & fees

Stay at this apartment in Charleston. Enjoy laundry facilities, tennis courts, and patios. Popular attractions South Carolina Aquarium and Charleston City Market are located nearby.

Kitchen

Washer

Historic District Downtown 344 & A Half On King Street

Charleston SC

Get rates

Stay at this apartment in Charleston. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Charleston City Market and South Carolina Aquarium are located nearby.

Historic District Downtown 344 King Street

Charleston SC

Get rates

Stay at this apartment in Charleston. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Charleston City Market and South Carolina Aquarium are located nearby.

Don't see what you're looking for?

See all available properties in South Carolina

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Carolina Adults Only Resorts & Hotels essential information

Adults Only Resorts & Hotels in South Carolina	42
Highest price	CA $1,353
Cheapest price	CA $85
Total number of hotels in South Carolina	54,140
Popular hotels	86 Cannon Charleston - Adults Only, Affordable Suites Myrtle Beach, Baymont by Wyndham Orangeburg North, Beach Lover's Condo With Spectacular Ocean View, Pool, Lazy River, & Jacuzzi! , Detached Guest Suite, Downtown-One-of-a-Kind Romantic Luxury Residence 5BR, 3BA Sleeps 10 to 12, Historic District Downtown 344 & A Half On King Street, Historic District Downtown 344 King Street