Book spa resorts in Panama City from CA $116

Top Panama City Spa Resorts & Hotels

Bristol Panama, a Registry Collection Hotel

Avenida Aquilino de La Guardia Panama City Panama

Free cancellation

Reserve now, pay when you stay

CA $254

CA $279 total

Dec 12 - Dec 13

includes taxes & fees

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Free cancellation

Reserve now, pay when you stay

CA $160

CA $176 total

Dec 8 - Dec 9

includes taxes & fees

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

Las Americas Golden Tower Panama

Av. Balboa con Calle 53 Panama City Panama

Free cancellation

Reserve now, pay when you stay

CA $219

CA $244 total

Dec 14 - Dec 15

includes taxes & fees

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...

JW Marriott Panama

Calle Punta Colon, Punta Pacifica Panama City Panama

Free cancellation

Reserve now, pay when you stay

CA $351

CA $386 total

Jan 4 - Jan 5, 2026

includes taxes & fees

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, 4 outdoor pools, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

56 y 57 East Street, Obarrio Panama City Panama

Free cancellation

Reserve now, pay when you stay

CA $220

CA $242 total

Dec 8 - Dec 9

includes taxes & fees

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and a casino. Our guests praise the helpful staff and the clean rooms in ...

Decapolis Hotel Panama City

Avenida Balboa Con Multicentro Panama City Panama

Free cancellation

Reserve now, pay when you stay

CA $105

CA $116 total

Dec 14 - Dec 15

includes taxes & fees

Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff ...

Megapolis Hotel Panamá

Ave. Balboa al lado de Multicentro, 63 Panama City Panamá Province

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Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 4 restaurants. Popular attractions Albrook Shopping Mall and Avenida ...

Sheraton Grand Panama

Via Israel And 77th Street Panama City Panama

Free cancellation

Reserve now, pay when you stay

CA $187

CA $205 total

Dec 13 - Dec 14

includes taxes & fees

Book a stay at this spa resort in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the property condition ...

The Westin Playa Bonita Panama

Km 6 Road to Veracruz Veracruz Panama

Free cancellation

Reserve now, pay when you stay

CA $242

CA $266 total

Dec 15 - Dec 16

includes taxes & fees

Book a stay at this luxury hotel in Veracruz. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...

Dreams Playa Bonita Panama - All Inclusive

KM 7, Road to Veracruz Veracruz Panama

Free cancellation

Reserve now, pay when you stay

CA $376

CA $376 total

Dec 18 - Dec 19

includes taxes & fees

Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...

Waymore Hotel Spa and Casino

Via Veneto Y Avenida Eusebio Morales Panama City Panamá Province

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Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Avenida ...

Eurostars Panama City

Calle Ricardo Arias Panama City Panama

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Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a casino. Popular attractions Albrook Shopping Mall and Avenida Balboa are ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

There is nothing more refreshing than a day at the spa. And the pure joy of spa hotels in Panama City will make you feel rejuvenated and relaxed. Pamper yourself while in Panama City with a massage, a calming facial, or relaxation in the sauna or steam room. Spa hotels in Panama City offer everything you need to feel ultimate tranquility. So book today on Travelocity to find deals on Panama City spa hotel and prepare to relax.

Panama City hotels essential information

Accommodation	1,630 hotels
Lowest Price	CA $116
Highest Price	CA $386
Popular hotels	Bristol Panama, a Registry Collection Hotel, Decapolis Hotel Panama City, Megapolis Hotel Panamá, Sortis Hotel, Spa & Casino, Autograph Collection by Marriott, Dreams Playa Bonita Panama - All Inclusive, Las Americas Golden Tower Panama, JW Marriott Panama, Eurostars Panama City, The Westin Playa Bonita Panama, Waymore Hotel Spa and Casino, Sheraton Grand Panama, Hotel Riu Plaza Panama