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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
3-star hotel near Duke University

Choose dates to view prices

Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.
Exterior
Lobby lounge
Fitness facility
In-room safe, desk, laptop workspace, blackout drapes

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Parking available

Explore the area

View in a map
1108 West Main Street, Durham, NC, 27701
  • Place, Brightleaf Square
    ‪3 min walk‬
  • Place, Duke University
    ‪3 min walk‬
  • Place, Durham Performing Arts Center
    ‪16 min walk‬
  • Airport, Raleigh, NC (RDU-Raleigh - Durham Intl.)
    ‪19 min drive‬

Room options

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

8.8 out of 10
Excellent
(6 reviews)
  • 44 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed

9.0 out of 10
Wonderful
(37 reviews)
  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 Queen Bed with Sofa bed

A modern hotel room with a bed, a TV, a kitchenette, and a dining area.

Studio, 1 Queen Bed with Sofa bed

9.8 out of 10
Exceptional
(16 reviews)
  • 39 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Hearing Accessible)

A hotel room with a bed, a desk, a chair, and a TV.

Suite, 1 Bedroom (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

10.0 out of 10
Exceptional
(1 review)
  • 44 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout drapes

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

A hotel room with a bed, a desk, a chair, and a TV.

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

  • 40 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, Multiple Beds (Mobility Accessible, Tub)

Suite, Multiple Beds (Mobility Accessible, Tub)

Suite, Multiple Beds (Mobility Accessible, Tub)

8.0 out of 10
Very good
(2 reviews)
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

A hotel room with a bed, a desk, a chair, and a TV.

Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free WiFi

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About the area

Durham

Trinity Park stay.At this Trinity Park hotel, you'll be within a 5-minute walk of Duke University and Brightleaf Square. Carolina Theatre and Durham Convention Center are also within half a mile (1 km).

What's nearby

  • Brightleaf Square - 3 min walk - 0.3 km
  • Duke University - 3 min walk - 0.3 km
  • Durham Convention Center - 12 min walk - 1.1 km
  • Durham Performing Arts Center - 16 min walk - 1.4 km
  • Durham Bulls Athletic Park - 18 min walk - 1.5 km

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 21 min drive

Restaurants

  • ‪The Federal - ‬3 min walk
  • ‪Atomic Clock Brewing Co - ‬11 min walk
  • ‪Grub Durham - ‬12 min walk
  • ‪The Can Opener - ‬7 min walk
  • ‪It's A Southern Thing - ‬7 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

3-star hotel near Duke University
A computer station is on site and WiFi is free in public spaces. You'll find a business center on site. Free breakfast is available daily. Event space at this hotel measures 2530 square feet (235 square meters) and includes conference space. A 24-hour fitness center, a terrace, and coffee/tea in a common area are also featured at the business-friendly Residence Inn Durham McPherson/Duke University Medical Cntr. The hotel can provide concierge services, a complimentary grocery shopping service, and wedding services. Parking is available for a fee. A complete renovation of Residence Inn Durham McPherson/Duke University Medical Cntr was completed in April 2024.

This 3-star Durham hotel is smoke free.

  • 147 guestrooms or units
  • 5 levels
  • 2530 sq ft of conference space
  • 235 sq m of conference space
  • Built in 2015
  • To-go breakfast (free)
  • Business facilities
  • Conference space
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-in
  • Express check-out
  • Storage area for luggage
  • Front-desk safe
  • Concierge
  • Grocery service (free)
  • Wedding services available
  • Convenience store
  • Terrace
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Elevator
  • No smoking on site
Residence Inn Durham McPherson/Duke University Medical Cntr offers 147 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas and include dining tables. 32-inch Smart televisions come with premium cable channels, pay movies, and Netflix. Accommodations at this 3-star hotel have kitchens with full-sized refrigerators/freezers, stovetops, microwaves, and cookware/dishes/utensils. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers.

This Durham hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

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Property amenities

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

Room amenities

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 100.00 per pet (varies based on length of stay)
  • Maximum 2 (weight limit: 100 lbs per pet)
  • Restrictions apply
  • For more information, you can reach out to the property at the number on the booking confirmation
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Union Pay. Cash is not accepted. For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, and a smoke detector in each accommodation. This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott).

We should mention

  • To make arrangements to bring your pet, contact the property directly at the number on your booking confirmation (please see the Fees section for related charges).
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

How close is Residence Inn Durham McPherson/Duke University Medical Cntr to the airport?

Residence Inn Durham McPherson/Duke University Medical Cntr is 15 mi (21-min drive) away from the Raleigh-Durham International Airport (RDU) airport, the closest popular airport to the property.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of Jul 17, 2026, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on Aug 2, 2026 start from CA $185, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Residence Inn Durham McPherson/Duke University Medical Cntr have an airport shuttle?

Airport shuttle services are not available at Residence Inn Durham McPherson/Duke University Medical Cntr.

Does Residence Inn Durham McPherson/Duke University Medical Cntr offer free breakfast?

Residence Inn Durham McPherson/Duke University Medical Cntr offers free on-the-go breakfast every day from 7:00 AM to 9:00 AM.

Is there a casino at Residence Inn Durham McPherson/Duke University Medical Cntr?

No, there is no casino at this hotel.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; Check-in end time: midnight.

Is there free parking at Residence Inn Durham McPherson/Duke University Medical Cntr?

Free parking is not available at this hotel. Self parking is available for USD 15 per day.

Does Residence Inn Durham McPherson/Duke University Medical Cntr have a pool?

Residence Inn Durham McPherson/Duke University Medical Cntr does not have a pool.

Does Residence Inn Durham McPherson/Duke University Medical Cntr have a spa?

There are no spa services available at this hotel.

How close is Residence Inn Durham McPherson/Duke University Medical Cntr to downtown Durham?

Residence Inn Durham McPherson/Duke University Medical Cntr is 0.7 mi away from Durham.

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 328 out of 482 reviews
Rating 8 - Good. 107 out of 482 reviews
Rating 6 - Okay. 29 out of 482 reviews
Rating 4 - Poor. 7 out of 482 reviews
Rating 2 - Terrible. 11 out of 482 reviews

9.4/10

Cleanliness

9.2/10

Staff & service

8.8/10

Amenities

9.4/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

RICHARD

Liked: Cleanliness, staff & service, property conditions & facilities
Great downtown location
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Anna F

Liked: Cleanliness, amenities, property conditions & facilities
Courteous staff, spotless rooms, comfortable bed and pillows.
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was great - very friendly staff.
Stayed 2 nights in Sep 2025
Verified

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities
We love this hotel. The staff is excellent and the rooms are well designed and comfortable. The breakfast is delicious.
Stayed 10 nights in Dec 2025
Verified

10/10 Excellent

Syreeta

Liked: Cleanliness, staff & service, amenities
Rooms were spacious and spotless. Customer Service was phenomenal! Housekeeping were friendly and had no problems giving the extra items needed, including extra pillows.
Stayed 2 nights in Feb 2026
Verified

8/10 Good

Minor

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

Tim

Liked: Cleanliness, staff & service, amenities
Great stay. The hotel breakfast left a little something to be desired but the room was clean, the staff was helpful. This was everything I expected.
Stayed 2 nights in Nov 2025
Verified

6/10 Okay

Susan

Liked: Cleanliness, amenities, property conditions & facilities
Wi-Fi did not work and we were not told the procedure for paying for parking. Received a $20 ticket.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Judy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location with some incredible Restaurants nearby
Stayed 3 nights in Oct 2024
Verified

10/10 Excellent

Derek

Liked: Cleanliness, staff & service, property conditions & facilities
Was very nice. The staff was very polite when we arrived.
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great and reasonably priced place to stay as a family in the center of Durham.
Stayed 1 night in Sep 2024
Verified

8/10 Good

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel for the price. Good location. Big rooms. Quiet. Easy parking. Could be a little cleaner.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Jackson

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean room,good breakfast and great staff.
Stayed 4 nights in Nov 2022
Verified

10/10 Excellent

Wendy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, friendly, great location.
Stayed 1 night in Sep 2024
Verified

10/10 Excellent

Christopher

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place!
Stayed 3 nights in Dec 2023
Verified

10/10 Excellent

Jo Anne

Liked: Cleanliness, staff & service, property conditions & facilities
Great place
Stayed 2 nights in May 2024
Verified

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025
Verified

8/10 Good

Heman

Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025
Verified

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025
Verified

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Mustafa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
comfortable stay
Stayed 3 nights in Nov 2023
Verified

10/10 Excellent

Barbara

Liked: Cleanliness, staff & service, property conditions & facilities
Breakfast was great.
Stayed 3 nights in Jan 2024
Verified

10/10 Excellent

Timothy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location in Durham!
Stayed 1 night in Apr 2024
Verified

8/10 Good

nicole

Liked: Cleanliness, staff & service, property conditions & facilities
Clean room. Lighting in bathroom needs to be better.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Kelly

Liked: Property conditions & facilities
Very nice staff and very clean!
Stayed 1 night in Feb 2024