
Book Cheap American Airlines flight from Detroit (DTW) to Cusco (CUZ) from CA $806
Find The Best Day to Book a Cheap American Airlines Flights From Detroit to Cusco
Cheapest American Airlines Flights from Detroit (DTW) to Cusco (CUZ)
The cheapest flights to Alejandro Velasco Astete Intl. found within the past 7 days were CA $1,573 round trip and CA $806 one way. Prices and availability subject to change. Additional terms may apply.
Grab a great American Airlines flight from DTW to CUZ
To find a great deal on American Airlines flights with Travelocity, simply enter your origin and destination airports, pick your travel dates, and hit search. From here, you can sort by price, flight duration, and arrival/departure time. You can also filter to find nonstop flights.
Flying American Airlines Detroit to Cusco gives you fights to choose from. With that direct flight time of , you’ll be touching down before you know it.
Find cheap flights with American Airlines between Detroit and Cusco
American Airlines has a range of great fares on stacks of flights, and to find the most affordable for you, there are a few tricks you can try. Booking in advance, for example, is a great way to grab a fantastic deal. Also, choose the cheapest month, if you can. One-way flights from Detroit to Cusco with American Airlines are January.
The more flexible you are, the more affordable flights you’re likely to find. Consider one-way flights and connecting flights, as well as standard roundtrip and direct options. Even if you’re flying today, cheap last-minute flights are easy to find by entering your travel dates and hitting search.
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Airport code | Country | Airport name | Number of flights |
|---|---|---|---|
| DFW | USA | Dallas-Fort Worth Intl. | 599 |
| CLT | USA | Charlotte-Douglas Intl. | 536 |
| ORD | USA | O'Hare Intl. | 317 |
| PHL | USA | Philadelphia Intl. | 247 |
| MIA | USA | Miami Intl. | 193 |
| DCA | USA | Ronald Reagan Washington National | 152 |
| PHX | USA | Sky Harbor Intl. | 141 |
| LAX | USA | Los Angeles Intl. | 81 |
| LGA | USA | LaGuardia | 72 |
| BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to Cusco

Hotel Paradis Suite - Cusco
Great experience at this hotel. Staff is extremely friendly and helpful. The hotel itself is very clean and accommodating would highly recommend
Reviewed on Nov 14, 2025

Sonesta Hotel Cusco
Nice hotel with great breakfast
Reviewed on Dec 17, 2025

Ureta Hotel
Excellent service, very clean room
Reviewed on Dec 17, 2025
Want more than a(n) American Airlines Flight from Detroit to Cusco?
Popular American Airlines Flight Routes from DTW
Domestic
- Toronto to Montego Bay (YYZ - MBJ)
- Montreal to Paris (YUL - CDG)
- Toronto to Las Vegas (YYZ - LAS)
- Toronto to Karachi (YYZ - KHI)
- Toronto to Orlando (YYZ - MCO)
- Toronto to Punta Cana (YYZ - PUJ)
- Vancouver to Delhi (YVR - DEL)
- Montreal to Fort Lauderdale (YUL - FLL)
- Toronto to Cancun (YYZ - CUN)
- Toronto to Mumbai (YYZ - BOM)
International
- Toronto to Orlando (YYZ - MCO)
- Toronto to Lahore (YYZ - LHE)
- Toronto to Punta Cana (YYZ - PUJ)
- Montreal to Cancun (YUL - CUN)
- Toronto to Karachi (YYZ - KHI)
- Calgary to Delhi (YYC - DEL)
- Toronto to Dubai (YYZ - DXB)
- Montreal to Las Vegas (YUL - LAS)
- Toronto to Delhi (YYZ - DEL)
- Toronto to Mumbai (YYZ - BOM)
Most Popular
- Delta Kincheloe (CIU) to Fort Lauderdale (FLL) flights
- Delta Kincheloe (CIU) to Detroit (DTW) flights
- United Calgary (YYC) to Cusco (CUZ) flights
- Winnipeg to Manila (YWG - MNL)
- Air Canada Toronto (YYZ) to Cusco (CUZ) flights
- Delta Toronto (YYZ) to Traverse City (TVC) flights
- Delta Kincheloe (CIU) to Las Vegas (LAS) flights
- Vancouver to Kalamazoo (YVR - AZO)
- Sault Ste. Marie to Orlando (CIU - MCO)
- Vancouver to Lansing (YVR - LAN)
- Delta Kincheloe (CIU) to Puerto Vallarta (PVR) flights
- WestJet Montreal (YUL) to Calgary (YYC) flights
- Bahamasair Nassau (NAS) to Freeport (FPO) flights
- Delta Kincheloe (CIU) to Tampa (TPA) flights
- Toronto to Tel Aviv (YYZ - TLV)
- Toronto to Saginaw (YYZ - MBS)
- Sault Ste. Marie to Nashville (CIU - BNA)
- Sault Ste. Marie to Minneapolis (CIU - MSP)
- LATAM Airlines Group Vancouver (YVR) to Cusco (CUZ) flights
- Sault Ste. Marie to Fort Myers (CIU - RSW)
- Delta Minneapolis - St. Paul (MSP) to Kincheloe (CIU) flights
- Delta Detroit (DTW) to Kincheloe (CIU) flights
