
Book Cheap American Airlines flight from McAllen (MFE) to San Diego (SAN)
Find The Best Day to Book a Cheap American Airlines Flights From McAllen to San Diego
Frequently asked questions
Grab a great American Airlines flight from MFE to SAN
To find a great deal on American Airlines flights with Travelocity, simply enter your origin and destination airports, pick your travel dates, and hit search. From here, you can sort by price, flight duration, and arrival/departure time. You can also filter to find nonstop flights.
Flying American Airlines McAllen to San Diego gives you fights to choose from. With that direct flight time of , you’ll be touching down before you know it.
Find cheap flights with American Airlines between McAllen and San Diego
American Airlines has a range of great fares on stacks of flights, and to find the most affordable for you, there are a few tricks you can try. Booking in advance, for example, is a great way to grab a fantastic deal. Also, choose the cheapest month, if you can. One-way flights from McAllen to San Diego with American Airlines are .
The more flexible you are, the more affordable flights you’re likely to find. Consider one-way flights and connecting flights, as well as standard roundtrip and direct options. Even if you’re flying today, cheap last-minute flights are easy to find by entering your travel dates and hitting search.
Reasons to book your American Airlines flights with Travelocity
Travelocity makes it easy to book a seat, anywhere in the world. The vast inventory, fast search, and advanced filters put some of the best deals on the planet in one place. Whether you’re traveling on business, with friends, family, or on your own, take your pick from some fantastic options. And with free cancellation and pay later options, you can travel more and worry less.
Airport code | Country | Airport name | Number of flights |
|---|---|---|---|
| DFW | USA | Dallas-Fort Worth Intl. | 599 |
| CLT | USA | Charlotte-Douglas Intl. | 536 |
| ORD | USA | O'Hare Intl. | 317 |
| PHL | USA | Philadelphia Intl. | 247 |
| MIA | USA | Miami Intl. | 193 |
| DCA | USA | Ronald Reagan Washington National | 152 |
| PHX | USA | Sky Harbor Intl. | 141 |
| LAX | USA | Los Angeles Intl. | 81 |
| LGA | USA | LaGuardia | 72 |
| BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to San Diego

Sheraton San Diego Resort
The room had a broken outlet but enough for me to use else where. However, my biggest issue was the lack of privacy and the cost cutting door they provide for bathroom. With the "budget" room they have a sliding slated barn door. For the price of this room I'm disappointed in the privacy, or lack ...
Reviewed on Mar 19, 2026

Wyndham San Diego Bayside
Great spot!!
Reviewed on Mar 21, 2026

The DEXTRO Little Italy, BW Premier Collection
Stayed for 4 nights and found the location to be pretty central to everything else which made it walkable so that was nice. Staff was helpful and accommodating Pool was small but nice
Reviewed on Mar 21, 2026
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