
Book Cheap American Airlines flight from Roanoke (ROA) to San Diego (SAN)
Find The Best Day to Book a Cheap American Airlines Flights From Roanoke to San Diego
Frequently asked questions
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DFW | USA | Dallas-Fort Worth Intl. | 599 |
CLT | USA | Charlotte-Douglas Intl. | 536 |
ORD | USA | O'Hare Intl. | 317 |
PHL | USA | Philadelphia Intl. | 247 |
MIA | USA | Miami Intl. | 193 |
DCA | USA | Ronald Reagan Washington National | 152 |
PHX | USA | Sky Harbor Intl. | 141 |
LAX | USA | Los Angeles Intl. | 81 |
LGA | USA | LaGuardia | 72 |
BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to San Diego

Sheraton San Diego Resort
1380 Harbor Island Dr, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8/10 Very Good! (2,815 reviews)
"I would go back"
Reviewed on Jul. 14, 2025

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,729 reviews)
"We stayed in tier 3. Bathrooms could use an upgrade. We had to move to another room, our first room smelled musty and moldy. We were moved to new room with a harbor view. That was a plus. We did have to remind the front desk to clean our room. Upon returning from our first day out, our room had not ..."
Reviewed on Jul. 14, 2025

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (1,876 reviews)
"Good location"
Reviewed on Jul. 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Want more than a(n) American Airlines Flight from Roanoke to San Diego?
Domestic
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