Eastern Panama Vacations 2026 from CA $1,339

Eastern Panama flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

MARINN PLACE Financial District

Bella Vista

CA $1,339

per person

Jun 15 - Jun 22

found 20 hours ago

Roundtrip non-stop flight included

Montreal (YUL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Central Hotel Panama Casco Viejo

Casco Viejo

CA $1,885

per person

Jun 15 - Jun 22

found 20 hours ago

Roundtrip non-stop flight included

Montreal (YUL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Megapolis Hotel Panamá

San Francisco

CA $1,705

per person

May 30 - Jun 6

found 5 hours ago

Roundtrip non-stop flight included

Montreal (YUL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

CA $1,783

per person

Jun 15 - Jun 22

found 20 hours ago

Roundtrip non-stop flight included

Montreal (YUL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Multiplaza Pacific Mall and Avenida Balboa are located nearby.

Yoo by Wynwood House

Calidonia

CA $2,480

per person

Jul 5 - Jul 12

found 1 day ago

Roundtrip non-stop flight included

Toronto (YYZ) to Panama City (PTY)

Stay at this condo in Panama City. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Top Eastern Panama hotels deals

Ciel y Miel

Caillle Principale Cacique Provincia de Colón

CA $283

CA $312 total

May 5 - May 6

includes taxes & fees

Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island Narganá Guna Yala

Get rates

Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime are located nearby.

Ordovician Beach Resort

Isla Grande Isla Grande Colon

CA $615

CA $683 total

May 19 - May 20

includes taxes & fees

Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

CA $151

CA $166 total

May 4 - May 5

includes taxes & fees

Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Cocoloco - Catamaran Lagoon 52F SAN BLAS

El Porvenir Narganá Guna Yala

Free cancellation

Reserve now, pay when you stay

CA $2,729

CA $3,009 total

May 7 - May 8

includes taxes & fees

Book a stay at this beach property in San Blas Islands. Enjoy free breakfast, free WiFi, and a beach locale. Popular attractions Porvenir Museum and Isla Chichime are located nearby.

Konsenda San Blas

Llano Cartí Km 11 El Llano Panamá Province

Free cancellation

Reserve now, pay when you stay

CA $83

CA $92 total

May 26 - May 27

includes taxes & fees

Stay at this hotel in El Llano. Enjoy free breakfast, free parking, and a garden.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.

Isla Chichime

Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area.

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals.

Frequently asked questions

How much are vacation packages to Eastern Panama?

Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as CA $1,339. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.

Where can I get the best vacation package deals for Eastern Panama?

You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.

Why should I purchase my Eastern Panama vacation package with Travelocity?

We offer 24/7 support, top-quality service and a Price Match Guarantee. Life's a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.

Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?

Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.

What is there to do in Eastern Panama?

You'll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.