Eastern Panama Vacations 2026 from CA $1,243

Eastern Panama flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

Riande Aeropuerto Hotel & Casino

Tocumen Airport

CA $1,243

per person

Jan 8 - Jan 12

found 1 day ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

CA $4,977

per person

Dec 26 - Dec 31

found 1 day ago

Roundtrip flight included

Hamilton (YHM) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Casa Mallet by Wynwood House

Casco Viejo

CA $8,249

per person

Dec 27 - Jan 3

found 6 hours ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Hotel San Pedro de Taboga

CA $1,368

per person

Jan 25 - Jan 31

found 19 hours ago

Roundtrip non-stop flight included

Toronto (YYZ) to Panama City (PTY)

Stay at this hotel in Taboga. Enjoy free breakfast, free WiFi, and daily housekeeping. Popular attraction Taboga Beach is located nearby.

American Trade Hotel

Casco Viejo

CA $1,937

per person

Dec 10 - Dec 17

found 1 day ago

Roundtrip non-stop flight included

Toronto (YTO) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Top Eastern Panama hotels deals

Ordovician Beach Resort

Isla Grande Isla Grande Colon

CA $629

CA $693 total

Nov 4 - Nov 5

includes taxes & fees

Book a stay at this luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

On private beach

Pool

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island Narganá Guna Yala

CA $263

CA $289 total

Nov 5 - Nov 6

includes taxes & fees

Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime are located nearby.

Breakfast included

Restaurant

san blas luxury tour

guna yala Nusatupo Guna Yala

CA $151

CA $170 total

Nov 6 - Nov 7

includes taxes & fees

Book a stay at this beach cabin in Narganá. Enjoy free breakfast, free WiFi, and a private beach.

Breakfast included

Free WiFi

Ciel y Miel

Caillle Principale Cacique Provincia de Colón

CA $289

CA $318 total

Nov 4 - Nov 5

includes taxes & fees

Book a stay at this beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pool

Breakfast included

Ranchos de Chalia

Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón

CA $176

CA $194 total

Nov 5 - Nov 6

includes taxes & fees

Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pool

Breakfast included

Cocoloco - Catamaran Lagoon 52F SAN BLAS

El Porvenir Narganá Guna Yala

Get rates

Stay at this cruise ship in San Blas Islands. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Porvenir Museum and Isla Chichime are located nearby.

Breakfast included

Free WiFi

Don't see what you're looking for?

See all available properties in Eastern Panama

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Eastern Panama attractions

Isla Diablo

Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area.

See properties

Frequently asked questions

How much are vacation packages to Eastern Panama?

Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as CA $1,243. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.

Where can I get the best vacation package deals for Eastern Panama?

You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.

Why should I purchase my Eastern Panama vacation package with Travelocity?

We offer 24/7 support, top-quality service and a Price Match Guarantee. Life's a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.

Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?

Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.

What is there to do in Eastern Panama?

You'll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.