Eastern Panama Vacations 2025 from CA $1,215

Eastern Panama flight + hotel packages

Price found within the past 48 hours. Click for updated prices.

Villa Botero By Casa Mojito B&B

per person

Jul. 24 - Jul. 31

found 1 day ago

Roundtrip non-stop flight included

Toronto (YYZ) to Panama City (PTY)

Stay at this 3-star golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.

Residencia Natural

per person

Jun. 20 - Jun. 27

found 8 hours ago

Roundtrip non-stop flight included

Vancouver (YVR) to Panama City (PTY)

Stay at this 3-star beach aparthotel in Bastimentos. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Playa Larga and Nivida Bat Cave are located nearby.

Punta Caracol Acqua Lodge

Punta Caracol

Save 100% on your flight

per person

Jun. 20 - Jun. 27

found 8 hours ago

Roundtrip non-stop flight included

Vancouver (YVR) to Panama City (PTY)

Stay at this 3.5-star beach lodge in Bocas del Toro. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Gruta Cave and Institute for Tropical Ecology & Conservation - Bocas del Toro Biological Station are located nearby.

NAYARA Bocas del Toro

Save 100% on your flight

per person

Jun. 20 - Jun. 27

found 8 hours ago

Roundtrip non-stop flight included

Vancouver (YVR) to Panama City (PTY)

Stay at this 4-star spa hotel in Isla Frangipani. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews.

Top Eastern Panama hotels deals

Ordovician Beach Resort

Isla Grande, Isla Grande, Colon

CA $747

CA $822 total

includes taxes & fees

May 10 - May 11

Stay at this 4.5-star luxury resort in Isla Grande. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

On private beach

Pool

Private Over the Water Cabin on San Blas Island

9.542876, -78.899058, Narganá, San Blas

CA $289

CA $318 total

includes taxes & fees

May 12 - May 13

Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna Nation and Porvenir Museum are located nearby.

Breakfast included

Kitchen

San Blas Paradise Private Cabins on Shipwreck Island - meals included

Perro Island, Narganá, Guna Yala

CA $246

CA $271 total

includes taxes & fees

May 11 - May 12

Book a stay at this beach hotel in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attraction Museum of the Kuna Nation is located nearby.

Breakfast included

Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island, Narganá, Guna Yala

CA $289

CA $318 total

includes taxes & fees

May 11 - May 12

Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attraction Museum of the Kuna Nation is located nearby.

Breakfast included

Restaurant

Ciel y Miel

Caillle Principale, Cacique, Provincia de Colón

CA $320

CA $352 total

includes taxes & fees

May 11 - May 12

Stay at this 3-star beach hotel in Cacique. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Isla Mamey and Portobelo National Park are located nearby.

Pool

Breakfast included

Paradise Over the Water Cabins in San Blas

G4V2 48, Narganá, Guna Yala

CA $255

CA $418 total

includes taxes & fees

May 11 - May 12

Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Porvenir Museum and Museum are located nearby.

Breakfast included

Restaurant

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Cayos Holandeses

Commune with nature and explore the great outdoors at Cayos Holandeses during your travels in San Blas Islands. Stroll along the seaside or experience the area's festivals.

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Masargantupo. Stroll along the seaside or experience the area's festivals.

Porvenir Museum

You can spend time browsing the exhibits at Porvenir Museum during your travels in Narganá. Amble around the area's seaside or experience its festivals.

Frequently asked questions

How much are vacation packages to Eastern Panama?

Exciting adventures await in Eastern Panama, with Travelocity vacation packages starting from as low as CA $1,215. Including flights and hotels, these awesome deals make it a breeze to see more of our beautiful planet.

Where can I get the best vacation package deals for Eastern Panama?

You can snap up amazing Eastern Panama package deals with Travelocity. Mix and match from 400 air carriers and 1,000,000 worldwide properties and turn those travel dreams into a reality.

Why should I purchase my Eastern Panama vacation package with Travelocity?

We offer 24/7 support, top-quality service and a Price Match Guarantee. Life’s a great big journey — and we have alluring destinations for you to journey to all across the world. Wander with us and your wallet will thank you for it.

Can I save money on my Eastern Panama car rental if I bundle it with my hotel or flight?

Certainly. And our Eastern Panama vacation packages are the perfect way to do it. In just a few clicks you can save cash as well as time by bundling your bookings. Pick up the keys to your rental car and feel the freedom of the open road. Searching for things to do? Add some tours or experiences to your package and make savings on those too.

What is there to do in Eastern Panama?

You’ll be happy to know Eastern Panama is brimming with incredible things to see and do, however Isla Mamey and Cayos Holandeses are right up there with the very best.