Book spa resorts in Florence, SC from CA $148
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Top Florence Spa Resorts & Hotels
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
Free cancellation
The price is CA $150 per night
CA $150
CA $168 total
Jan 25 - Jan 26, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hampton Inn & Suites Florence Center
3000 W Radio Dr Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $133 per night
CA $133
CA $149 total
Jan 25 - Jan 26, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
The Mantissa Hotel
130 East Carolina Ave Hartsville SC
Free cancellation
Reserve now, pay when you stay
The price is CA $204 per night
CA $204
CA $229 total
Jan 5 - Jan 6, 2026
includes taxes & fees
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $157 per night
CA $157
CA $176 total
Jan 7 - Jan 8, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $178 per night
CA $178
CA $200 total
Jan 8 - Jan 9, 2026
includes taxes & fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
Residence Inn Marriott Florence
2660 Hospitality Blvd Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $136 per night
CA $136
CA $152 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Hilton Garden Inn Florence
2671 Hospitality Boulevard Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $136 per night
CA $136
CA $152 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this family-friendly hotel in Florence. Enjoy room service, a fitness center, and a garden. Our guests praise the helpful staff in our reviews. ...
SpringHill Suites by Marriott Florence
2670 Hospitality Blvd Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $147 per night
CA $147
CA $165 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Courtyard by Marriott Florence
2680 Hospitality Blvd Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $132 per night
CA $132
CA $148 total
Jan 18 - Jan 19, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
About Florence Spa Hotels
There is nothing more refreshing than a day at the spa. And the pure joy of spa hotels in Florence will make you feel rejuvenated and relaxed. Pamper yourself while in Florence with a massage, a calming facial, or relaxation in the sauna or steam room. Spa hotels in Florence offer everything you need to feel ultimate tranquility. So book today on Travelocity to find deals on Florence spa hotel and prepare to relax.
Florence hotels essential information
Accommodation | 366 hotels |
|---|---|
Lowest Price | CA $148 |
Highest Price | CA $229 |
Popular hotels | Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG, Courtyard by Marriott Florence, Hampton Inn & Suites Florence Center, Hampton Inn & Suites Florence-North-I-95, Hilton Garden Inn Florence, Hotel Florence, Tapestry Collection by Hilton, Residence Inn Marriott Florence, SpringHill Suites by Marriott Florence, The Mantissa Hotel |
Recent Florence hotel reviews by fellow wanderers
Hampton Inn & Suites Florence-North-I-95
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Easy check in with Valerie."
A verified traveller stayed at Hampton Inn & Suites Florence-North-I-95
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