Northeast Missouri Vacations 2026

Top Northeast Missouri hotels deals

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Free cancellation

Reserve now, pay when you stay

CA $139

CA $162 total

Apr 19 - Apr 20

includes taxes & fees

Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions St. Louis Zoo and Forest Park are located nearby.

Pool

Breakfast included

Pear Tree Inn St. Louis Near Union Station

2211 Market Street St. Louis MO

Free cancellation

Reserve now, pay when you stay

CA $158

CA $184 total

Apr 13 - Apr 14

includes taxes & fees

Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions St. Louis Union Station and Enterprise Center are located nearby.

Pool

Hot tub

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Free cancellation

Reserve now, pay when you stay

CA $200

CA $241 total

May 3 - May 4

includes taxes & fees

Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our reviews. Popular attractions St. Louis Union Station and Busch Stadium are located nearby.

Pool

Spa

Hollywood Casino & Hotel St. Louis

777 Casino Center Drive Maryland Heights MO

Free cancellation

Reserve now, pay when you stay

CA $153

CA $199 total

Apr 7 - Apr 8

includes taxes & fees

Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Hollywood Casino Amphitheatre and Ameristar Casino St. Charles are located nearby.

Free airport shuttle

Parking included

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

Free cancellation

Reserve now, pay when you stay

CA $125

CA $148 total

Apr 12 - Apr 13

includes taxes & fees

Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Hollywood Casino Amphitheatre and Payne-Gentry Historical House are located nearby.

Drury Inn & Suites St. Louis Union Station

201 S 20th St St. Louis MO

Free cancellation

Reserve now, pay when you stay

CA $201

CA $239 total

Apr 19 - Apr 20

includes taxes & fees

Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions St. Louis Union Station and Busch Stadium are located nearby.

Pool

Hot tub

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

St. Louis Zoo

Why not visit the animals who live at St. Louis Zoo and see why this is a popular attraction in St. Louis? Amble around the area's lush forest or attend a sporting event.

Frequently asked questions

How much are vacation packages to Northeast Missouri?

You might be surprised — you can vacation in Northeast Missouri for a mere . Allow Travelocity to save you money and stress with our vacation packages. With flights, hotels and experiences all ready to go, what's holding you back?

Where can I get the best vacation package deals for Northeast Missouri?

Your dream vacation can be booked through Travelocity. With access to 400 airlines and 1,000,000 properties worldwide, creating the ultimate Northeast Missouri package deal couldn't be easier.

Why should I purchase my Northeast Missouri vacation bundle via Travelocity?

We offer experiences and destinations to suit every type of globetrotter, exceptional service and 24/7 customer support. And to top it off, we'll match any cheaper price you're able to find with our Price Match Guarantee.

Can I save on my Northeast Missouri car rental if I book it with my hotel or flight?

Sure can. And our Northeast Missouri vacation packages are the ideal way to do it. With only a few clicks you can save money as well as time by booking everything in one place. Collect the keys to your rental car and feel the freedom of the open road. Need to fill your itinerary? Add some activities or experiences to your package and save on those too.

Which airport is best for Northeast Missouri?

Quincy Regional-Baldwin Field Airport (UIN) and Kirksville Municipal Airport (IRK) are the best options for flying to Northeast Missouri.

What is there to do in Northeast Missouri?

A vibrant and impressive destination, Northeast Missouri offers some wonderful things to see and do. Busch Stadium and Gateway Arch are a couple of the favorites.