Book a hotel near Enterprise Center, Downtown West

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Hotels near Enterprise Center

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Free cancellation
Reserve now, pay when you stay
0.52 km from Enterprise Center
The price is CA $185 per night
CA $185
CA $223 total
Dec 29 - Dec 30
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our reviews. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
Pool
Spa
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4 out of 5
1820 Market Street St. Louis MO
Free cancellation
Reserve now, pay when you stay
0.52 km from Enterprise Center
The price is CA $216 per night
CA $216
CA $257 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this historic hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 7 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
Pool
Pet-friendly
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
1221 Locus Street St. Louis MO
Free cancellation
Reserve now, pay when you stay
0.61 km from Enterprise Center
The price is CA $108 per night
CA $108
CA $126 total
Dec 30 - Dec 31
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, valet parking (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
Breakfast included
Pet-friendly
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
Free cancellation
Reserve now, pay when you stay
0.63 km from Enterprise Center
The price is CA $164 per night
CA $164
CA $195 total
Dec 26 - Dec 27
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
Pool
Breakfast included
The Westin St. Louis

The Westin St. Louis

4.5 out of 5
811 Spruce St St. Louis MO
Free cancellation
Reserve now, pay when you stay
0.78 km from Enterprise Center
The price is CA $175 per night
CA $175
CA $204 total
Dec 29 - Dec 30
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and valet parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pet-friendly
Restaurant
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
0.82 km from Enterprise Center
The price is CA $206 per night
CA $206
CA $245 total
Dec 23 - Dec 24
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the bar and the helpful staff in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pet-friendly
Free WiFi
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Free cancellation
Reserve now, pay when you stay
0.93 km from Enterprise Center
The price is CA $130 per night
CA $130
CA $152 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant in our reviews. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
Pool
Hot tub
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Free cancellation
Reserve now, pay when you stay
0.99 km from Enterprise Center
The price is CA $111 per night
CA $111
CA $131 total
Dec 25 - Dec 26
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pet-friendly
Free WiFi
Marriott St. Louis Grand

Marriott St. Louis Grand

4 out of 5
800 Washington Ave St. Louis MO
Free cancellation
Reserve now, pay when you stay
1.03 km from Enterprise Center
The price is CA $175 per night
CA $175
CA $208 total
Dec 26 - Dec 27
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Free WiFi
Restaurant
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Free cancellation
Reserve now, pay when you stay
1.22 km from Enterprise Center
The price is CA $186 per night
CA $186
CA $218 total
Dec 26 - Dec 27
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pool
Hot tub
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Free cancellation
Reserve now, pay when you stay
1.3 km from Enterprise Center
The price is CA $137 per night
CA $137
CA $161 total
Dec 23 - Dec 24
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pet-friendly
Free WiFi
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
Free cancellation
Reserve now, pay when you stay
1.44 km from Enterprise Center
The price is CA $135 per night
CA $135
CA $157 total
Dec 28 - Dec 29
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pool
Breakfast included
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

About Enterprise Center Hotels Near Attractions

Do you have a full travel itinerary while visiting Enterprise Center? Don't waste your time commuting too far from Enterprise Center area attractions.

Enterprise Center hotels essential information

Accommodation
1,375 hotels
Lowest Price
CA $126
Highest Price
CA $257
Popular hotels
Hyatt Regency St. Louis at The Arch, Hampton Inn St. Louis-Downtown (At the Gateway Arch), Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, 21C Museum Hotel St Louis , Drury Plaza Hotel St. Louis at the Arch, Home2 Suites by Hilton St. Louis Downtown, Drury Inn & Suites St. Louis Union Station, Live by Loews - St.Louis, St. Louis Union Station Hotel, Curio Collection by Hilton, The Westin St. Louis, Pear Tree Inn St. Louis Near Union Station, Marriott St. Louis Grand

Recent Enterprise Center hotel reviews by fellow wanderers

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

5 out of 5
Posted 20 hours ago
Travelocity Verified Review
"Greatroom"
A verified traveller stayed at Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch

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