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Tonight
Check prices in Defiance for tonight, May 27 - May 28
May 27 - May 28
Tomorrow night
Check prices in Defiance for tomorrow night, May 28 - May 29
May 28 - May 29
This weekend
Check prices in Defiance for this weekend, May 29 - May 31
May 29 - May 31
Next weekend
Check prices in Defiance for next weekend, Jun 5 - Jun 7
Jun 5 - Jun 7

Most frequently booked Defiance hotels

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Free cancellation
Reserve now, pay when you stay
29.2 km from city centre
The price is CA $144 per night
CA $144
CA $188 total
Jun 2 - Jun 3
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Hollywood Casino Amphitheatre and Ameristar Casino St. Charles are located nearby.
Free airport shuttle
Parking included
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Free cancellation
Reserve now, pay when you stay
28.84 km from city centre
The price is CA $137 per night
CA $137
CA $159 total
May 28 - May 29
includes taxes & fees
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Simpson Park and LIFECHURCH are located nearby.
Pool
Hot tub
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl Wildwood MO
14.1 km from city centre
The price is CA $126 per night
CA $126
CA $147 total
Jun 23 - Jun 24
includes taxes & fees
Book a stay at this business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Six Flags St. Louis and Skid Row are located nearby.
Pool
Hot tub
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Free cancellation
Reserve now, pay when you stay
29.49 km from city centre
The price is CA $242 per night
CA $242
CA $306 total
May 28 - May 29
includes taxes & fees
Book a stay at this luxury hotel in St. Charles. Enjoy a full-service spa, 6 restaurants, and a casino. Our guests praise the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Pool
Hot tub
La Quinta Inn & Suites by Wyndham St. Louis Westport

La Quinta Inn & Suites by Wyndham St. Louis Westport

3 out of 5
11805 Lackland Rd Maryland Heights MO
Free cancellation
Reserve now, pay when you stay
30.67 km from city centre
The price is CA $132 per night
CA $132
CA $153 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Hollywood Casino Amphitheatre and Ameristar Casino St. Charles are located nearby.
Pool
Free airport shuttle
Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

3.5 out of 5
11228 Lone Eagle Dr Bridgeton MO
Free cancellation
35.17 km from city centre
The price is CA $209 per night
CA $209
CA $247 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in Bridgeton. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular attractions Hollywood Casino Amphitheatre and Ameristar Casino St. Charles are located nearby.
Pool
Free airport shuttle
WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon

2.5 out of 5
7850 Veterans Memorial Parkway St. Peters MO
Free cancellation
Reserve now, pay when you stay
21.55 km from city centre
The price is CA $101 per night
CA $101
CA $120 total
Jun 15 - Jun 16
includes taxes & fees
Stay at this hotel in St. Peters. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Bowlero St. Peters and CarShield Field are located nearby.
Pet-friendly
Parking included
Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis

3 out of 5
5 Lambert Drury Place (I-44 & 141) Valley Park MO
Free cancellation
Reserve now, pay when you stay
26.64 km from city centre
The price is CA $156 per night
CA $156
CA $183 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in Valley Park. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Simpson Park and Bowlero Lakeside are located nearby.
Pool
Hot tub
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4 out of 5
1335 S Lindbergh Blvd Frontenac MO
Free cancellation
Reserve now, pay when you stay
32.34 km from city centre
The price is CA $191 per night
CA $191
CA $223 total
Jun 21 - Jun 22
includes taxes & fees
Book a stay at this business-friendly hotel in Frontenac. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Creve Coeur Golf Club and Saint Louis Galleria Mall are located nearby.
Pool
Free airport shuttle
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See all available properties in Defiance
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top hotels in Defiance for Extended Stay

Comfort Meets Style–Boutique Experience-Buck Suite

Comfort Meets Style–Boutique Experience-Buck Suite

Saint Charles MO
9/10 Wonderful! (13 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Defiance hotels essential information

Accommodation
867 hotels
Lowest Price
CA $120
Highest Price
CA $725
Popular hotels
Hollywood Casino & Hotel St. Louis, Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, The Wildwood Hotel, Ameristar Casino Resort and Spa, La Quinta Inn & Suites by Wyndham St. Louis Westport, Crowne Plaza St. Louis Airport by IHG, WoodSpring Suites St Peters-OFallon, Drury Inn & Suites Southwest St. Louis, Hilton St. Louis Frontenac

Frequently asked questions

What are the top kid-friendly hotels in Defiance?
Family getaways are where lifelong memories are made, but it's no secret that traveling with young ones can be difficult. These kid-friendly Defiance hotels come with perks designed to keep guests of all ages comfortable and happy: The Ruebling House Historic Defiance Apartment! will help make your getaway the best one yet. It comes with plenty of nice little touches, such as free WiFi and extra bedding. Otherwise, spend your Defiance trip at 'The Reubling House' - Modern-Rustic Cabin!. Make the most of a barbecue grill, internet access and more here.
Where can I find cheap hotels in Defiance?
At Travelocity you'll find really nice hotels in Defiance at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Defiance rather than in Defiance. We may find you even better rates, too.
How do I find the best Defiance hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Defiance then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Defiance?
The cheapest hotel in Defiance is CA $120 This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Defiance?
There are 867 hotels in Defiance on Travelocity.
What are the best hotels in Defiance?
Defiance has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Defiance for you!
When is the best time to visit Defiance?
If you want the joy of a fun-filled trip in peak season, visit Defiance during March, April and May. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Defiance?
Based on historic data is usually the cheapest month to visit Defiance. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Defiance?
There are multiple hotels in Defiance that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Defiance. We have plenty of kid-friendly hotels in Defiance to choose from on Travelocity!
Why book a hotel in Defiance through Travelocity?
Because we have the top hotels in Defiance! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Defiance on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Defiance hotel reviews by fellow wanderers

Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Good clean room staff courteous"
A verified traveller stayed at Crowne Plaza St. Louis Airport by IHG
Crowne Plaza St. Louis Airport by IHG