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Tonight
Check prices in Defiance for tonight, Aug 27 - Aug 28
Aug 27 - Aug 28
Tomorrow night
Check prices in Defiance for tomorrow night, Aug 28 - Aug 29
Aug 28 - Aug 29
This weekend
Check prices in Defiance for this weekend, Aug 28 - Aug 30
Aug 28 - Aug 30
Next weekend
Check prices in Defiance for next weekend, Sep 4 - Sep 6
Sep 4 - Sep 6

Most frequently booked Defiance hotels

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Free cancellation
Reserve now, pay when you stay
29.2 km from city center
The price is CA $138 per night
CA $138
per night
Sep 1 - Sep 2
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Hollywood Casino Amphitheatre and Ameristar Casino St. Charles are located nearby.
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Free cancellation
Reserve now, pay when you stay
28.84 km from city center
The price is CA $131 per night
CA $131
per night
Aug 30 - Aug 31
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Simpson Park and Flight Range are located nearby.
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Free cancellation
Reserve now, pay when you stay
29.49 km from city center
The price is CA $221 per night
CA $221
per night
Sep 7 - Sep 8
Book a stay at this luxury hotel in St. Charles. Enjoy a full-service spa, 6 restaurants, and a casino. Our guests praise the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Pool
Hot tub
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
2801 Fountain Pl Wildwood MO
Free cancellation
Reserve now, pay when you stay
14.1 km from city center
The price is CA $110 per night
CA $110
per night
Sep 7 - Sep 8
Book a stay at this business-friendly hotel in Wildwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Six Flags St. Louis and Skid Row are located nearby.
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2.5 out of 5
1970 Craig Rd Maryland Heights MO
Free cancellation
Reserve now, pay when you stay
29.97 km from city center
The price is CA $94 per night
CA $94
per night
Aug 30 - Aug 31
Stay at this hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Westport Plaza and Hollywood Casino Amphitheatre are located nearby.
Pool
Breakfast included
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

3 out of 5
355 Chesterfield Ctr Chesterfield MO
Free cancellation
Reserve now, pay when you stay
18.97 km from city center
The price is CA $180 per night
CA $180
per night
Sep 3 - Sep 4
Book a stay at this business-friendly hotel in Chesterfield. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Chesterfield Amphitheater and Chesterfield Central Park are located nearby.
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4 out of 5
1335 S Lindbergh Blvd Frontenac MO
Free cancellation
Reserve now, pay when you stay
32.34 km from city center
The price is CA $204 per night
CA $204
per night
Sep 6 - Sep 7
Book a stay at this business-friendly hotel in Frontenac. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. Popular attractions Westport Plaza and Creve Coeur Golf Club are located nearby.
Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66

3 out of 5
1100 S Highway Dr Fenton MO
Free cancellation
Reserve now, pay when you stay
28.81 km from city center
The price is CA $116 per night
CA $116
per night
Aug 30 - Aug 31
Book a stay at this business-friendly hotel in Fenton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Simpson Park and Flight Range are located nearby.
Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

3 out of 5
11980 Olive Blvd St. Louis MO
Free cancellation
Reserve now, pay when you stay
29.07 km from city center
The price is CA $179 per night
CA $179
per night
Sep 27 - Sep 28
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Westport Plaza and Hollywood Casino Amphitheatre are located nearby.
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See all available properties in Defiance
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top hotels in Defiance for Extended Stay

Comfort Meets Style–Boutique Experience-Buck Suite

Comfort Meets Style–Boutique Experience-Buck Suite

Saint Charles MO
9/10 Wonderful! (16 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Defiance hotels essential information

Accommodation
880 hotels
Lowest Price
CA $109
Highest Price
CA $281
Popular hotels
Hollywood Casino & Hotel St. Louis, Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, Ameristar Casino Resort and Spa, The Wildwood Hotel, Days Inn and Suites by Wyndham St. Louis/Westport Plaza, Drury Plaza Hotel St. Louis Chesterfield, Hilton St. Louis Frontenac, Wingate by Wyndham St. Louis/Fenton Route 66, Drury Plaza Hotel St. Louis Creve Coeur

Frequently asked questions

What are the top kid-friendly hotels in Defiance?
Family getaways are where lifelong memories are made, but it's no secret that traveling with young ones can be difficult. These kid-friendly Defiance hotels come with perks designed to keep guests of all ages comfortable and happy: The Ruebling House Historic Defiance Apartment! will help make your getaway the best one yet. It comes with plenty of nice little touches, such as free WiFi and extra bedding. Otherwise, spend your Defiance trip at 'The Reubling House' - Modern-Rustic Cabin!. Make the most of a barbecue grill, internet access and more here.
Where can I find cheap hotels in Defiance?
At Travelocity you'll find really nice hotels in Defiance at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Defiance rather than in Defiance. We may find you even better rates, too.
How do I find the best Defiance hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Defiance then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Defiance?
The cheapest hotel in Defiance is CA $109 This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Defiance?
There are 880 hotels in Defiance on Travelocity.
What are the best hotels in Defiance?
Defiance has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Defiance for you!
When is the best time to visit Defiance?
If you want the joy of a fun-filled trip in peak season, visit Defiance during March, April and May. If you'd prefer the peace of off-season, book a stay during quieter months, such as December, January and February.
When is the cheapest time to stay in Defiance?
Based on historic data is usually the cheapest month to visit Defiance. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Defiance?
There are multiple hotels in Defiance that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Defiance. We have plenty of kid-friendly hotels in Defiance to choose from on Travelocity!
Why book a hotel in Defiance through Travelocity?
Because we have the top hotels in Defiance! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Defiance on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Defiance hotel reviews by fellow wanderers

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"We really enjoyed our stay. The price compared to other hotels in the area was much less and with traveling on a budget was very helpful. My kids loved the pool!"
A verified traveller stayed at Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology Drive