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Hotels near Central West End

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $180 per night from Feb 11 to Feb 12
CA $180
CA $210 total
Feb 11 - Feb 12
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
Front desk staff were extremely nice.

Reviewed on Feb 2, 2026

Opens in a new windowDrury Plaza Hotel St. Louis at the Arch
AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End

4 out of 5
215 YORK AVENUE St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $191 per night from Feb 22 to Feb 23
CA $191
CA $225 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and ...
Room was clean nice staff

Reviewed on Feb 2, 2026

Opens in a new windowAC Hotel St. Louis Central West End
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $240 per night from Feb 9 to Feb 10
CA $240
CA $323 total
Feb 9 - Feb 10
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, an outdoor pool, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in ...
+

Reviewed on Feb 4, 2026

Opens in a new window The Royal Sonesta Chase Park Plaza St. Louis
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $184 per night from Feb 22 to Feb 23
CA $184
CA $222 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
Everything was perfect!

Reviewed on Feb 1, 2026

Opens in a new window21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $144 per night from Feb 26 to Feb 27
CA $144
CA $169 total
Feb 26 - Feb 27
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Lovely hotel. Great breakfast

Reviewed on Jan 29, 2026

Opens in a new windowClayton Plaza Hotel & Extended Stay
Aloft St. Louis Cortex

Aloft St. Louis Cortex

3 out of 5
4245 Duncan Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $165 per night from Mar 9 to Mar 10
CA $165
CA $193 total
Mar 9 - Mar 10
includes taxes & fees
Stay at this hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
Friendly staff that greeted me at check-in

Reviewed on Jan 26, 2026

Opens in a new windowAloft St. Louis Cortex
The West End

The West End

2 out of 5
4215 Lindell Blvd St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $117 per night from Feb 8 to Feb 9
CA $117
CA $164 total
Feb 8 - Feb 9
includes taxes & fees
Stay at this hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Popular attractions St. Louis Union Station and Gateway ...
Clean room

Reviewed on Feb 6, 2026

Opens in a new windowThe West End
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $176 per night from Feb 28 to Mar 1
CA $176
CA $208 total
Feb 28 - Mar 1
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Nice room & friendly staff!

Reviewed on Jan 28, 2026

Opens in a new windowHyatt Regency St. Louis at The Arch
DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
4550 Forest Park Ave St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $167 per night from Feb 22 to Feb 23
CA $167
CA $197 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Very accessible if you're working or will be going to BJC. Spacious room. Courteous staff.

Reviewed on Feb 1, 2026

Opens in a new windowDoubleTree by Hilton St. Louis Forest Park
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Central West End Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Central West End area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Central West End to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Central West End are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Central West End hotel reviews by fellow wanderers