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Domus 21 Luxury Suites

5-star luxury guest house near Pantheon, connected to a rail/subway station

Choose dates to view prices

Photo gallery for Domus 21 Luxury Suites

A grand hallway with ornate columns and a high ceiling.
A modern living room with a green sofa, a dining table with a vase of flowers, a large mirror, and a chandelier.
A grand entrance with a marble floor, a large arched doorway, and a staircase leading inside.
A bedroom with a bed, a nightstand, a mirror, and a ceiling with intricate design.
A wooden door with a brass doorknob leading to a hallway with a carpeted floor and a light source at the end.

Reviews

9.8 out of 10
Exceptional

Popular amenities

  • Pet friendly
  • Free WiFi
  • Air conditioning
  • Laundry
  • Housekeeping

Explore the area

View in a map
Corso Vittorio Emanuele II 21, Rome, RM, 00186
  • Place, Teatro Faiano
    ‪1 min walk‬
  • Place, Piazza della Minerva
    ‪2 min walk‬
  • Place, Largo di Torre Argentina
    ‪2 min walk‬
  • Airport, Rome (FCO-Fiumicino - Leonardo da Vinci Intl.)
    ‪29 min drive‬

Room options

View all photos for Superior Room, 1 Queen Bed, Courtyard View

A hotel room with a bed, a desk, a chair, a TV, and a window with a view.

Superior Room, 1 Queen Bed, Courtyard View

10.0 out of 10
Exceptional
(2 reviews)
  • 20 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 Queen Bed
  • Free WiFi

View all photos for Deluxe Room, City View

A hotel room with a large bed, a window with a view of buildings, a small table with a lamp, and a chair.

Deluxe Room, City View

9.6 out of 10
Exceptional
(5 reviews)
  • City view
  • 24 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed OR 2 Twin Beds
  • Free WiFi

View all photos for Junior Suite

A hotel room with a bed, a desk, a chair, a TV, and a window with a view of a building.

Junior Suite

10.0 out of 10
Exceptional
(3 reviews)
  • City view
  • 40 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Grand Room

A modern bedroom with a large bed, bedside tables, a mirror, and decorative plants.

Grand Room

  • City view
  • 34 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed
  • Free WiFi

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About the area

Rome

Rome City Centre stay.At this Rome City Centre guesthouse, you'll be well placed to visit Pantheon and Piazza Venezia, both within a 5-minute walk. Piazza Navona and Campo de' Fiori are also within half a mile (1 km).
View more Guest houses in RomeOpens in a new window

What's nearby

  • Teatro Faiano - 1 min walk - 0.0 km
  • Piazza della Minerva - 2 min walk - 0.2 km
  • Elephant Obelisk - 2 min walk - 0.2 km
  • Chiesa del Gesù - 2 min walk - 0.2 km
  • Largo di Torre Argentina - 2 min walk - 0.2 km

Getting around

  • Venezia Tram Stop - 4 min walk
  • Rome San Pietro Station - 5 min drive
  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO) - 40 min drive

Restaurants

  • ‪Slow - ‬4 min walk
  • ‪Alice Pizza Largo Argentina - ‬1 min walk
  • ‪Cafffè Camerino - ‬5 min walk
  • ‪PASTAEAT la pastapoke - ‬1 min walk
  • ‪Shari Vari - ‬5 min walk

About this property

Domus 21 Luxury Suites

5-star luxury guest house near Pantheon, connected to a rail/subway station
As a guest of Domus 21 Luxury Suites, you'll find tour/ticket assistance, concierge services, and complimentary newspapers in the lobby. Public spaces have free WiFi. An airport shuttle (available 24 hours) is available for a fee. The luxury Domus 21 Luxury Suites also features laundry facilities, dry cleaning/laundry services, and express check-in.

This 5-star Rome guesthouse is smoke free.

  • 6 guestrooms or units
  • Charging station for electric cars
  • Dry cleaning
  • Self-service laundry
  • Front desk (limited hours)
  • Express check-in
  • Express check-out
  • Storage area for luggage
  • Tour and ticket information
  • Concierge
  • Newspapers in lobby (free)
  • Elevator
  • No smoking on site
Domus 21 Luxury Suites offers 6 air-conditioned accommodations with minibars (stocked with some free items) and laptop-compatible safes. Pillowtop beds feature Egyptian cotton sheets, down comforters, and premium bedding. A pillow menu is available. This Rome guesthouse provides complimentary wired and wireless Internet access, with a WiFi speed of 500+ Mbps (good for 6+ people or 10+ devices).

Bathrooms include showers with rainfall showerheads, bathrobes, slippers, and designer toiletries. Business-friendly amenities include printers and complimentary newspapers. Additionally, rooms include espresso makers and complimentary bottled water. Hypo-allergenic bedding, irons/ironing boards, and change of towels can be requested. A nightly turndown service is provided and housekeeping is offered daily.

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Property amenities

Family friendly

  • Art supplies
  • Baby toys
  • Children's books
  • Children's games
  • Children's toys
  • High chair
  • In-room babysitting (surcharge)
  • In-room crib
  • Laundry facilities
  • Soundproofed rooms

Internet

  • Available in all rooms: Free WiFi and wired internet
  • In-room WiFi speed: 500+ Mbps (good for 6+ people or 10+ devices)
  • Available in some public areas: Free WiFi

Parking and transportation

  • Electric car charging station on site
  • Offsite parking within 1 mile (EUR 24 per day); discounts available
  • Street parking available
  • 24-hour roundtrip airport shuttle at scheduled times and on request for a surcharge

Food and drink

  • Couples/private dining
  • Private picnics

Things to do

  • Bicycle tours
  • Books
  • Helicopter/airplane tours
  • Private wine tours
  • Wine tours
  • Winery release events

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible airport shuttle
  • Elevator
  • Well-lit path to entrance

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Egyptian cotton sheets
  • Free crib
  • Hypo-allergenic bedding
  • Pillow menu
  • Pillowtop mattress

Bathroom

  • Bathrobes
  • Bidet
  • Designer toiletries
  • Hair dryer
  • Rainfall showerhead
  • Shampoo
  • Shower
  • Slippers
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Champagne service
  • Coffee/tea maker
  • Electric kettle
  • Espresso maker
  • Free bottled water
  • Free minibar (limited items)
  • Restaurant dining guides

More

  • Air conditioning
  • Cleaning products are eco-friendly
  • Composting
  • Connecting rooms available
  • Eco-friendly toiletries
  • Electrical adapters
  • Free daily newspapers
  • Iron/ironing board on request
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Printer
  • Recycling
  • Reusable coffee/tea filters
  • Soundproofed rooms
  • Water-efficient showers
  • Water-efficient toilets

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: 11:00 AM
Contactless check-in available
Express check-in available
Minimum check-in age: 15

Check-out

Check-out before 11:00 AM
Contactless check-out available
Express check-out available

Special check-in instructions

This property offers transfers from the airport (surcharges may apply); to arrange pick-up, guests must contact the property 24 hours prior to arrival, using the contact information on the booking confirmation
The front desk is open daily from 9:00 AM - 5:00 PM
Guests planning to arrive outside of normal check-in hours must contact the property in advance for check-in instructions and key retrieval information; front desk staffed during limited hours
To make arrangements for check-in please contact the property at least 24 hours before arrival using the information on the booking confirmation
If you are planning to arrive after 2:00 PM please contact the property in advance using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Front desk (limited hours), key retrieval

Pets

  • Pets are welcome and stay free
  • Only dogs and cats are allowed
  • Maximum 4 (weight limit: 22 lbs per pet)
  • Pets cannot be left unattended
  • Food and water bowls, pet-sitting services, litter boxes, and pet grooming services are available

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • A tax is imposed by the city: EUR 5.00 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Airport shuttle fee: EUR 80 per vehicle (one-way, maximum occupancy 2)
  • Airport shuttle fee per child: EUR 80 (one-way), (up to 18 years old)
  • Nearby parking fee: EUR 24 per day (3281 ft away)

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards, and cash
Cashless transactions are available
Safety features at this property include a fire extinguisher, a security system, a first aid kit, and window guards
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, Union Pay, debit cards, and cash. For guests' safety, the property includes a fire extinguisher, a security system, a first aid kit, and window guards in each accommodation. Cashless payment methods are available for all transactions and guests can access their rooms with a mobile device.

Property Registration Number IT058091B4OUIRD7WF

We should mention

  • All guests (including children) need to be present at check-in to show their government-issued photo ID or passport.
  • Onsite cash transactions can't exceed EUR 5000, due to national regulations. For more details, please contact the property using information in the booking confirmation.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.

Property is also known as

Domus 21 Luxury Suites Rome
Domus 21 Luxury Suites Guesthouse
Domus 21 Luxury Suites Guesthouse Rome

Frequently asked questions

How close is Domus 21 Luxury Suites to the airport?

Domus 21 Luxury Suites is 9.8 mi (45-min drive) away from the Ciampino Airport (CIA) airport, the closest popular airport to the property.

How much does it cost to stay at Domus 21 Luxury Suites?

As of Jul 30, 2026, prices found for a 1-night stay for 2 adults at Domus 21 Luxury Suites on Aug 18, 2026 start from CA $231, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Domus 21 Luxury Suites have an airport shuttle?

Domus 21 Luxury Suites offers an airport shuttle 24 hours a day, at scheduled times, for a charge of EUR 80 per vehicle, one-way.

Does Domus 21 Luxury Suites offer free breakfast?

Domus 21 Luxury Suites does not offer free breakfast.

Is there a casino at Domus 21 Luxury Suites?

No, there is no casino at this guesthouse.

What time is check-in at Domus 21 Luxury Suites?

Check-in start time: 2:00 PM; Check-in end time: 11:00 AM.

Is there free parking at Domus 21 Luxury Suites?

Free parking is not available at this guesthouse.

Does Domus 21 Luxury Suites have a pool?

Domus 21 Luxury Suites does not have a pool.

Does Domus 21 Luxury Suites have a spa?

There are no spa services available at this guesthouse.

How close is Domus 21 Luxury Suites to downtown Rome?

Domus 21 Luxury Suites is 0.5 mi away from Rome.

Domus 21 Luxury Suites Reviews

Reviews

9.8

Exceptional

Rating 10 - Excellent. 94 out of 111 reviews
Rating 8 - Good. 14 out of 111 reviews
Rating 6 - Okay. 2 out of 111 reviews
Rating 4 - Poor. 0 out of 111 reviews
Rating 2 - Terrible. 1 out of 111 reviews

9.8/10

Cleanliness

9.8/10

Staff & service

9.4/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Erick

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good location, clean, private and comfortable suites.
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Audra

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely room and host, fantastic location
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Jacob

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The coolest hotel we stayed at on our Europe trip. Also the front desk woman Eleanora was extremely kind and so helpful and made our trip in Rome so much better. I 100% recommend coming here for a stay!
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Alison

Perfect location to see all of Rome on foot. Beautiful room. Wonderful helpful staff.
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Patrick

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff & location
Stayed 1 night in Oct 2025
Verified

6/10 Okay

Mary

First I will say housekeeping was outstanding.
Stayed 4 nights in Feb 2026
Verified

8/10 Good

Robert

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Good one night stay, hotel is in a perfect location to visit the sites.
Stayed 1 night in Aug 2025
Verified

8/10 Good

Neil

Liked: Cleanliness, staff & service, amenities
Was shown the room and amenities. Great location
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Deanna

Liked: Cleanliness, amenities, property conditions & facilities
Very lovely property! Close to so many restaurants, shopping, bus stops and site seeing.
Stayed 4 nights in Jun 2025
Verified

10/10 Excellent

Yuri

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very good location and stylish
Stayed 2 nights in Nov 2024
Verified

10/10 Excellent

Robert Anthony

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location and very accommodating!
Stayed 6 nights in Apr 2023
Verified

10/10 Excellent

Mikeala

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely size rooms that are really clean and quiet. Great location and friendly reception staff
Stayed 4 nights in Oct 2024
Verified

10/10 Excellent

Jeffrey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice staff. Great location
Stayed 1 night in Apr 2025
Verified

10/10 Excellent

Heidi

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Love this hotel!!! Awesome location, very nice inside, beds are super comfortable and staff was friendly and helpful! It also has a lift, which is great when u don’t pack light:-) They do not 24 reception so if you are arriving early or late you will just need to make arrangements.
Stayed 1 night in Oct 2025
Verified

8/10 Good

Julie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Convenient, clean guesthouse in Rome.
Stayed 1 night in Jun 2024
Verified

10/10 Excellent

Sean

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect Stay in Rome

Great location. Super clean. Friendly staff. Comfy bed. Hot shower. Everything I needed for my stay in Rome.
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Eusebio Dan

Liked: Cleanliness, staff & service, property conditions & facilities
Staff were kind and approachable! Location is amazing
Stayed 3 nights in May 2023
Verified

10/10 Excellent

Jose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent location and service. Even though the hotel doesn't have a 24 hr reception, the staff is invaluable with anything, and the size of the room and location are superb.
Stayed 5 nights in Apr 2025
Verified

10/10 Excellent

Mert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice spacious, clean rooms in a historical building.
Stayed 1 night in Jul 2022
Verified

10/10 Excellent

Cynthia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great location!

Nice place to stay! Perfect location, close to almost everything! Clean & very friendly staff. We would not hesitate to stay here again.
Stayed 2 nights in Jun 2023
Verified

10/10 Excellent

Angela

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Absolutely wonderful hotel. Unbelievably quiet and extremely convenient to all the major sites. The staff was excellent and easy to work with and we loved the beverages/snacks made available daily.
Verified

8/10 Good

Dennis

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Location, location, location. Great restaurants all around. Walkable to Trevi, the Colosseum and Pantheon.
Stayed 3 nights in Mar 2025
Verified

10/10 Excellent

Leslie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful accommodations and top notch service by Gregorio and Jane. The hotel accommodations were lovely, the location was central and convenient, and definitely enhanced our stay in Rome.
Stayed 4 nights in Jul 2022
Verified

10/10 Excellent

Nhu

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is exceptional space to spend time in Rome. The staff and rooms are superior. Their space is very aesthetic and the attention to detail in their design did not go unnoticed. I would not hesitate to stay here again! Thank you for the beautiful accommodations!
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Alexandra

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

10/10 recommend

Everything was amazing! We were at first a little confused on where to go once inside, but quickly figured it out and the concierge was so helpful in getting our bags into our room so we can go explore! We would def stay here again !
Stayed 1 night in Jul 2025