Book Cheap Hotels in Southeast Missouri
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check hotel availability in Southeast Missouri
Most frequently booked Southeast Missouri hotels
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Free cancellation
Reserve now, pay when you stay
75.5 km from city centre
The price is CA $126 per night
CA $126
CA $143 total
Oct 26 - Oct 27
includes taxes & fees
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are located nearby.
Pool
Hot tub
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
Free cancellation
Reserve now, pay when you stay
61.18 km from city centre
The price is CA $79 per night
CA $79
CA $90 total
Oct 26 - Oct 27
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Wilson Rozier Park and Veterans Park are located nearby.
Pool
Breakfast included
The Riverview
777 Main St, Cape Girardeau, MO
Free cancellation
Reserve now, pay when you stay
81.09 km from city centre
The price is CA $151 per night
CA $151
CA $171 total
Oct 26 - Oct 27
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are located nearby.
Parking included
Free WiFi
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
Free cancellation
Reserve now, pay when you stay
73.6 km from city centre
The price is CA $118 per night
CA $118
CA $128 total
Oct 20 - Oct 21
includes taxes & fees
Stay at this 3-star business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cape Girardeau Conservation Nature Center and Lazy L Safari Park are located nearby.
Pool
Breakfast included
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
Free cancellation
Reserve now, pay when you stay
46.95 km from city centre
The price is CA $111 per night
CA $111
CA $117 total
Oct 29 - Oct 30
includes taxes & fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located nearby.
Pet-friendly
Parking included
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Free cancellation
Reserve now, pay when you stay
87.75 km from city centre
The price is CA $88 per night
CA $88
CA $101 total
Nov 2 - Nov 3
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Breakfast included
Pet-friendly
Comfort Inn Festus - St Louis South
1303 Veterans Blvd, Festus, MO
Free cancellation
Reserve now, pay when you stay
110.13 km from city centre
The price is CA $112 per night
CA $112
CA $131 total
Nov 2 - Nov 3
includes taxes & fees
Book a stay at this business-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Sunset Park and Jorkerst Memorial Park are located nearby.
Breakfast included
Parking included
The Farmstead Hotel
778 E 3rd St, Caruthersville, MO
Free cancellation
Reserve now, pay when you stay
134.14 km from city centre
The price is CA $108 per night
CA $108
CA $123 total
Oct 19 - Oct 20
includes taxes & fees
Stay at this hotel in Caruthersville. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Century Casino Caruthersville and Caruthersville Public Library are located nearby.
Parking included
Free WiFi
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Free cancellation
Reserve now, pay when you stay
75.8 km from city centre
The price is CA $98 per night
CA $98
CA $111 total
Oct 19 - Oct 20
includes taxes & fees
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cape Splash Family Aquatic Center and Fort D Historic Site are located nearby.
Pet-friendly
Free WiFi
Don't see what you're looking for?
See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top family friendly Southeast Missouri hotel deals
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
The price is CA $126 per night from Oct 26 to Oct 27
CA $126
CA $145 total
Oct 26 - Oct 27
includes taxes & fees
9.4/10 Exceptional! (1,008 reviews)
Top cheap Southeast Missouri hotel deals
Motel 6 Poplar Bluff, MO
4101 Highway 67 N, Poplar Bluff, MO
The price is CA $111 per night from Oct 29 to Oct 30
CA $111
CA $117 total
Oct 29 - Oct 30
includes taxes & fees
7.8/10 Good! (1,014 reviews)
Top hotels in Southeast Missouri for Extended Stay
The King Suite at Pickle & Perk
Ironton
The price is CA $188 per night from Oct 19 to Oct 20
CA $188
CA $249 total
Oct 19 - Oct 20
includes taxes & fees
10/10 Exceptional! (1 review)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 594 hotels |
|---|---|
Lowest Price | CA $82 |
Highest Price | CA $249 |
Popular hotels | Drury Plaza Hotel Cape Girardeau Conference Center, Baymont Inn and Suites by Wyndham Farmington, MO, The Riverview, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Motel 6 Poplar Bluff, MO, Days Inn and Suites by Wyndham Sikeston, Comfort Inn Festus - St Louis South, The Farmstead Hotel, Pear Tree Inn Cape Girardeau Near the Medical Center |
Recent Southeast Missouri hotel reviews by fellow wanderers
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Wonderful facility- top to bottom "
A verified traveller stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Types of hotels
Hotels near…
Areas of Southeast Missouri
More ways to wander Southeast Missouri
Most popular
Hotels
- Hotels in Parkville
- All Inclusive Resorts & Hotels in Oahu
- All Inclusive Resorts & Hotels in Kauai
- All Inclusive Resorts & Hotels in Maui
- Hotels with Waterslides in Northwest Montana - Glacier National Park
- Beach Resorts & Hotels in Cape Cod
- Golf Resorts & Hotels in Upstate New York
- Hotels in Kauai
- All Inclusive Resorts & Hotels in Cape Cod
- Casino Resorts & Hotels in Wenatchee - Lake Chelan
- Hotels in Maui
- Waterpark Hotels and Resorts in Upstate New York
- Beach Resorts & Hotels in Maui
- Waterpark Hotels and Resorts in Niagara Falls - Western New York
- Hotels in Oahu
- Hotels in Cape Cod
Activities
