Book Cheap Hotels in Southeast Missouri
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Most frequently booked Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free cancellation
Reserve now, pay when you stay
87.14 km from city centre
The price is CA $140 per night
CA $140
CA $161 total
Apr 29 - Apr 30
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Pool
Breakfast included

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free cancellation
Reserve now, pay when you stay
75.5 km from city centre
The price is CA $137 per night
CA $137
CA $154 total
May 3 - May 4
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are located nearby.
Pool
Hot tub

The Riverview
777 Main St Cape Girardeau MO
Free cancellation
Reserve now, pay when you stay
81.09 km from city centre
The price is CA $165 per night
CA $165
CA $186 total
May 3 - May 4
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Century Casino & Hotel Cape Girardeau and Riverfront Park are located nearby.
Parking included
Free WiFi

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Free cancellation
Reserve now, pay when you stay
73.6 km from city centre
The price is CA $122 per night
CA $122
CA $132 total
Apr 19 - Apr 20
includes taxes & fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cape Girardeau Conservation Nature Center and Cape Splash Family Aquatic Center are located nearby.
Pool
Breakfast included

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free cancellation
Reserve now, pay when you stay
85 km from city centre
The price is CA $139 per night
CA $139
CA $158 total
May 3 - May 4
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Pool
Breakfast included

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Free cancellation
Reserve now, pay when you stay
73.05 km from city centre
The price is CA $114 per night
CA $114
CA $120 total
May 3 - May 4
includes taxes & fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attraction Litz Park is located nearby.
Pool
Hot tub

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free cancellation
Reserve now, pay when you stay
61.18 km from city centre
The price is CA $82 per night
CA $82
CA $89 total
Apr 29 - Apr 30
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Wilson Rozier Park and Veterans Park are located nearby.
Pool
Breakfast included

Silo Farm Haus- located in the heart of wine country!
Ste. Genevieve MO
66.09 km from city centre
The price is CA $327 per night
CA $327
CA $478 total
Apr 20 - Apr 21
includes taxes & fees
Stay at this farm stay in Ste Genevieve. Enjoy laundry facilities. Popular attractions Crown Valley Winery and Hawn State Park are located nearby.
Laundry

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Free cancellation
Reserve now, pay when you stay
46.95 km from city centre
The price is CA $100 per night
CA $100
CA $105 total
Apr 19 - Apr 20
includes taxes & fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located nearby.
Pet-friendly
Parking included
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See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top family friendly Southeast Missouri hotel deals

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
The price is CA $140 per night from Apr 29 to Apr 30
CA $140
CA $161 total
Apr 29 - Apr 30
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
Top cheap Southeast Missouri hotel deals

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
The price is CA $100 per night from Apr 19 to Apr 20
CA $100
CA $105 total
Apr 19 - Apr 20
includes taxes & fees
8/10 Very Good! (1,002 reviews)
Top hotels in Southeast Missouri for Extended Stay

The King Suite at Pickle & Perk
Ironton MO
The price is CA $184 per night from Apr 19 to Apr 20
CA $184
CA $261 total
Apr 19 - Apr 20
includes taxes & fees
10/10 Exceptional! (2 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 651 hotels |
|---|---|
Lowest Price | CA $89 |
Highest Price | CA $478 |
Popular hotels | Drury Inn & Suites Sikeston, MO, Drury Plaza Hotel Cape Girardeau Conference Center, The Riverview, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Hampton Inn Sikeston, Drury Inn & Suites Jackson MO, Baymont Inn and Suites by Wyndham Farmington, MO, Silo Farm Haus- located in the heart of wine country!, Motel 6 Poplar Bluff, MO |
Recent Southeast Missouri hotel reviews by fellow wanderers

Motel 6 Poplar Bluff, MO
5 out of 5
Posted 14 hours ago
Travelocity Verified Review
"Clean room, easy parking, loved that our room had seat in the shower. Made it easier for me while recovering from ankle surgery. Always love motel 6 for being pet friendly and having a 24 hour lobby. Makes a world of difference while traveling."
A verified traveller stayed at Motel 6 Poplar Bluff, MO
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