Book spa resorts in Florence, SC from CA $151
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Top Florence Spa Resorts & Hotels

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
3440 W Radio Dr Florence SC
The price is CA $164 per night
CA $164
CA $184 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

The Mantissa Hotel
130 East Carolina Ave Hartsville SC
Free cancellation
Reserve now, pay when you stay
The price is CA $207 per night
CA $207
CA $232 total
Apr 8 - Apr 9
includes taxes & fees
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

Hampton Inn & Suites Florence Center
3000 W Radio Dr Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $175 per night
CA $175
CA $196 total
Apr 30 - May 1
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

Hampton Inn & Suites Florence-North-I-95
1735 Stokes Road Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $164 per night
CA $164
CA $184 total
Apr 8 - Apr 9
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Hotel Florence, Tapestry Collection by Hilton
126 W Evans St Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $181 per night
CA $181
CA $203 total
Apr 26 - Apr 27
includes taxes & fees
Book a stay at this spa hotel in Florence. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...

Residence Inn Marriott Florence
2660 Hospitality Blvd Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $158 per night
CA $158
CA $177 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...

Hilton Garden Inn Florence
2671 Hospitality Boulevard Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $176 per night
CA $176
CA $197 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this family-friendly hotel in Florence. Enjoy room service, a fitness center, and a garden. Our guests praise the helpful staff in our reviews. ...

SpringHill Suites by Marriott Florence
2670 Hospitality Blvd Florence SC
Free cancellation
Reserve now, pay when you stay
The price is CA $135 per night
CA $135
CA $151 total
Apr 8 - Apr 9
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
About Florence Spa Hotels
There is nothing more refreshing than a day at the spa. And the pure joy of spa hotels in Florence will make you feel rejuvenated and relaxed. Pamper yourself while in Florence with a massage, a calming facial, or relaxation in the sauna or steam room. Spa hotels in Florence offer everything you need to feel ultimate tranquility. So book today on Travelocity to find deals on Florence spa hotel and prepare to relax.
Florence hotels essential information
Accommodation | 396 hotels |
|---|---|
Lowest Price | CA $151 |
Highest Price | CA $232 |
Popular hotels | Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG, Hampton Inn & Suites Florence Center, Hampton Inn & Suites Florence-North-I-95, Hilton Garden Inn Florence, Hotel Florence, Tapestry Collection by Hilton, Residence Inn Marriott Florence, SpringHill Suites by Marriott Florence, The Mantissa Hotel |
Recent Florence hotel reviews by fellow wanderers

Residence Inn Marriott Florence
5 out of 5
Posted 21 hours ago
Travelocity Verified Review
"Breakfast was great, clean room."
A verified traveller stayed at Residence Inn Marriott Florence
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