Book Cheap Hotels in O Brien
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Most frequently booked O Brien hotels

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
obrien FL
14.67 km from city centre
Book a stay at this beach vacation home in O Brien. Enjoy free WiFi, a beach locale, and a fitness center. Popular attractions Wes Skiles Peacock Springs State Park and Telford Spring are located nearby.
Kitchen
Washer

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
16367 NW 167TH BLVD Alachua FL
Free cancellation
48.18 km from city centre
The price is CA $148 per night
CA $148
CA $166 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Alachua Sports Complex and City of Alachua Recreation and Community Center are located nearby.
Pool
Hot tub

La Quinta Inn & Suite by Wyndham Lake City
165NW CALI DRIVE Lake City FL
Free cancellation
Reserve now, pay when you stay
29.34 km from city centre
The price is CA $143 per night
CA $143
CA $161 total
Feb 11 - Feb 12
includes taxes & fees
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Breakfast included

Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
1699 NE Co Rd 337 High Springs FL
39.7 km from city centre
The price is CA $163 per night
CA $163
CA $299 total
Mar 4 - Mar 5
includes taxes & fees
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ruth B. Kirby Gilchrist Blue Springs State Park and Poe Springs Park are located nearby.
Kitchen
Pet-friendly

Tru by Hilton Lake City
284 NW Centurion Court Lake City FL
Free cancellation
Reserve now, pay when you stay
28.85 km from city centre
The price is CA $147 per night
CA $147
CA $165 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Breakfast included

Courtyard By Marriott Lake City
3004 West US HWY 90 Lake City FL
Free cancellation
Reserve now, pay when you stay
29.37 km from city centre
The price is CA $146 per night
CA $146
CA $165 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Parking included

Best Western Plus Lake City
350 SW Florida Gateway Dr Lake City FL
Free cancellation
Reserve now, pay when you stay
28.81 km from city centre
The price is CA $157 per night
CA $157
CA $177 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Breakfast included

Holiday Inn Express & Suites Live Oak by IHG
6694 Us Highway 129 Live Oak FL
Free cancellation
32.24 km from city centre
The price is CA $165 per night
CA $165
CA $181 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this business-friendly hotel in Live Oak. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Suwannee County Historical Museum and First Federal Sportsplex are located nearby.
Pool
Breakfast included

Holiday Inn & Suites Lake City by IHG
213 Sw Commerce Dr Lake City FL
Free cancellation
29.15 km from city centre
The price is CA $134 per night
CA $134
CA $151 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this business-friendly hotel in Lake City. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Pet-friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
O Brien hotels essential information
Accommodation | 355 hotels |
|---|---|
Lowest Price | CA $151 |
Highest Price | CA $299 |
Popular hotels | Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!, Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, La Quinta Inn & Suite by Wyndham Lake City, Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy, Tru by Hilton Lake City, Courtyard By Marriott Lake City, Best Western Plus Lake City, Holiday Inn Express & Suites Live Oak by IHG, Holiday Inn & Suites Lake City by IHG |
Frequently asked questions
Recent O Brien hotel reviews by fellow wanderers

Americas Best Value Inn Lake City
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Check in was smooth. Room was nice and clean. Young lady that checked us in was very nice and informative. We were here February 2025 with another couple. We had a good experience then, so we came back."
A verified traveller stayed at Americas Best Value Inn Lake City
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