Book Cheap Hotels in O Brien
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check hotel availability in O Brien
Most frequently booked O Brien hotels

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
14.67 km from city centre
Book a stay at this family-friendly vacation home in O Brien. Enjoy free WiFi, a beach locale, and a garden. Popular attractions Wes Skiles Peacock Springs State Park and Telford Spring are located nearby.
Kitchen
Washer

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
14.76 km from city centre
Stay at this vacation home in O Brien. Enjoy a garden, laundry facilities, and patios. Popular attractions Wes Skiles Peacock Springs State Park and Telford Spring are located nearby.
Kitchen
Washer

La Quinta Inn & Suite by Wyndham Lake City
165NW CALI DRIVE, Lake City, FL
Free cancellation
Reserve now, pay when you stay
29.33 km from city centre
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Breakfast included

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
16367 NW 167TH BLVD, Alachua, FL
Free cancellation
48.17 km from city centre
Stay at this 3.5-star business-friendly hotel in Alachua. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Alachua Sports Complex and City of Alachua Recreation and Community Center are located nearby.
Pool
Hot tub

Best Western Plus Lake City
350 SW Florida Gateway Dr, Lake City, FL
Free cancellation
Reserve now, pay when you stay
28.81 km from city centre
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Breakfast included

Tru by Hilton Lake City
284 NW Centurion Court, Lake City, FL
Free cancellation
Reserve now, pay when you stay
28.85 km from city centre
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Breakfast included

Holiday Inn Express Hotel & Suites LIVE OAK by IHG
6694 Us Highway 129, Live Oak, FL
Free cancellation
32.24 km from city centre
Book a stay at this business-friendly hotel in Live Oak. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Suwannee County Historical Museum and First Federal Sportsplex are located nearby.
Pool
Breakfast included

Postcard Cabins Gilchrist Springs
1699 NE Co Rd 337, High Springs, FL
39.7 km from city centre
Stay at this cabin in High Springs. Enjoy free parking, patios, and climate control. Popular attractions Ginnie Spring and Ruth B. Kirby Gilchrist Blue Springs State Park are located nearby.
Kitchen
Pet-friendly

Comfort Suites Lake City
3690 W Us Highway 90, Lake City, FL
Free cancellation
Reserve now, pay when you stay
28.56 km from city centre
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Regal UA Cinema 90 and Lake City Mall are located nearby.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top hotels in O Brien for Extended Stay

Experience the Best Hospitality in Lake City!
Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
O Brien hotels essential information
Accommodation | 328 hotels |
---|---|
Lowest Price | |
Highest Price | |
Popular hotels | Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!, MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY, La Quinta Inn & Suite by Wyndham Lake City, Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, Best Western Plus Lake City, Tru by Hilton Lake City, Holiday Inn Express Hotel & Suites LIVE OAK by IHG, Postcard Cabins Gilchrist Springs, Comfort Suites Lake City |
Frequently asked questions
Recent O Brien hotel reviews by fellow wanderers

Courtyard By Marriott Lake City
5 out of 5
Posted 5 hours ago
Travelocity Verified Review
"Rooms were new and clean. Nice bistro area downstairs for coffee and some food options. Nice area to work on my laptop."
A verified traveller stayed at Courtyard By Marriott Lake City
Hotels near…
Areas of O Brien
Most popular
Hotels
Flights
Activities