Book Cheap Hotels in Southeast Missouri
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Most frequently booked Southeast Missouri hotels

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Free cancellation
Reserve now, pay when you stay
75.5 km from city centre
The price is CA $136 per night
CA $136
CA $154 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are located nearby.
Pool
Hot tub

Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
Free cancellation
Reserve now, pay when you stay
75.26 km from city centre
The price is CA $123 per night
CA $123
CA $138 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are located nearby.
Pool
Hot tub

The Riverview
777 Main St Cape Girardeau MO
Free cancellation
Reserve now, pay when you stay
81.09 km from city centre
The price is CA $122 per night
CA $122
CA $138 total
Mar 10 - Mar 11
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and Riverfront Park are located nearby.
Parking included
Free WiFi

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
Free cancellation
Reserve now, pay when you stay
61.18 km from city centre
The price is CA $79 per night
CA $79
CA $89 total
Mar 12 - Mar 13
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Wilson Rozier Park and Veterans Park are located nearby.
Pool
Breakfast included

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free cancellation
Reserve now, pay when you stay
87.14 km from city centre
The price is CA $128 per night
CA $128
CA $147 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Central Park and Sikeston Depot Museum are located nearby.
Pool
Breakfast included

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Free cancellation
Reserve now, pay when you stay
73.6 km from city centre
The price is CA $115 per night
CA $115
CA $124 total
Mar 5 - Mar 6
includes taxes & fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Cape Girardeau Conservation Nature Center and Lazy L Safari Park are located nearby.
Pool
Breakfast included

Baymont by Wyndham Festus
1200 W. Gannon Drive Festus MO
Free cancellation
Reserve now, pay when you stay
109.74 km from city centre
The price is CA $111 per night
CA $111
CA $127 total
Mar 8 - Mar 9
includes taxes & fees
Book a stay at this family-friendly hotel in Festus. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Jorkerst Memorial Park and Sunset Park are located nearby.
Pool
Breakfast included

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Free cancellation
Reserve now, pay when you stay
46.95 km from city centre
The price is CA $89 per night
CA $89
CA $94 total
Mar 4 - Mar 5
includes taxes & fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located nearby.
Pet-friendly
Parking included

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Free cancellation
Reserve now, pay when you stay
73.05 km from city centre
The price is CA $109 per night
CA $109
CA $115 total
Mar 22 - Mar 23
includes taxes & fees
Book a stay at this business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Litz Park and Lazy L Safari Park are located nearby.
Pool
Hot tub
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See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top family friendly Southeast Missouri hotel deals

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
The price is CA $128 per night from Mar 8 to Mar 9
CA $128
CA $147 total
Mar 8 - Mar 9
includes taxes & fees
9.4/10 Exceptional! (1,007 reviews)
Top cheap Southeast Missouri hotel deals

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
The price is CA $89 per night from Mar 4 to Mar 5
CA $89
CA $94 total
Mar 4 - Mar 5
includes taxes & fees
8/10 Very Good! (1,003 reviews)
Top hotels in Southeast Missouri for Extended Stay

The King Suite at Pickle & Perk
Ironton MO
10/10 Exceptional! (2 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 627 hotels |
|---|---|
Lowest Price | CA $89 |
Highest Price | CA $154 |
Popular hotels | Drury Plaza Hotel Cape Girardeau Conference Center, Drury Inn & Suites Cape Girardeau, The Riverview, Baymont Inn and Suites by Wyndham Farmington, MO, Drury Inn & Suites Sikeston, MO, La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau, Baymont by Wyndham Festus, Motel 6 Poplar Bluff, MO, Drury Inn & Suites Jackson MO |
Recent Southeast Missouri hotel reviews by fellow wanderers

Baymont Inn and Suites by Wyndham Farmington, MO
2 out of 5
Posted 9 hours ago
Travelocity Verified Review
"Went down to eat breakfast. The eggs were liquid and uncooked. Then went to get gravy for biscuts and gravy we found a long hair in the gravy. We have stayed here before and never had this issue. The beds do sleep great"
A verified traveller stayed at Baymont Inn and Suites by Wyndham Farmington, MO
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