
Book Cheap American Airlines flight from Minneapolis (MSP) to San Diego (SAN)
Find The Best Day to Book a Cheap American Airlines Flights From Minneapolis to San Diego
Cheapest American Airlines Flights from Minneapolis (MSP) to San Diego (SAN)
The cheapest flights to San Diego Intl. found within the past 7 days were CA $560 round trip and one way. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Grab a great American Airlines flight from MSP to SAN
To find a great deal on American Airlines flights with Travelocity, simply enter your origin and destination airports, pick your travel dates, and hit search. From here, you can sort by price, flight duration, and arrival/departure time. You can also filter to find nonstop flights.
Flying American Airlines Minneapolis - St. Paul to San Diego gives you fights to choose from. With that direct flight time of , you’ll be touching down before you know it.
Find cheap flights with American Airlines between Minneapolis - St. Paul and San Diego
American Airlines has a range of great fares on stacks of flights, and to find the most affordable for you, there are a few tricks you can try. Booking in advance, for example, is a great way to grab a fantastic deal. Also, choose the cheapest month, if you can. One-way flights from Minneapolis - St. Paul to San Diego with American Airlines are .
The more flexible you are, the more affordable flights you’re likely to find. Consider one-way flights and connecting flights, as well as standard roundtrip and direct options. Even if you’re flying today, cheap last-minute flights are easy to find by entering your travel dates and hitting search.
Reasons to book your American Airlines flights with Travelocity
Travelocity makes it easy to book a seat, anywhere in the world. The vast inventory, fast search, and advanced filters put some of the best deals on the planet in one place. Whether you’re traveling on business, with friends, family, or on your own, take your pick from some fantastic options. And with free cancellation and pay later options, you can travel more and worry less.
Airport code | Country | Airport name | Number of flights |
|---|---|---|---|
| DFW | USA | Dallas-Fort Worth Intl. | 599 |
| CLT | USA | Charlotte-Douglas Intl. | 536 |
| ORD | USA | O'Hare Intl. | 317 |
| PHL | USA | Philadelphia Intl. | 247 |
| MIA | USA | Miami Intl. | 193 |
| DCA | USA | Ronald Reagan Washington National | 152 |
| PHX | USA | Sky Harbor Intl. | 141 |
| LAX | USA | Los Angeles Intl. | 81 |
| LGA | USA | LaGuardia | 72 |
| BOS | USA | Logan Intl. | 57 |
Travelers ❤️ these 🏨 after their flight to San Diego

Sheraton San Diego Resort
Room was exceptionally clean!!
Reviewed on Mar 21, 2026

Wyndham San Diego Bayside
It is a nice hotel but the included Wi-fi is very slow. You get 3Mbps for free, which makes streaming slow and with lots of buffering, or you can pay an extra $10 per day directly to Cox Comms for 10Mbps which fixed the slow streaming for me.
Reviewed on Mar 22, 2026

The DEXTRO Little Italy, BW Premier Collection
It’s a good stay for a fair rate. Good location. The AC in our first room was ancient and broke down. They moved us to another room that was more updated. Wish we would’ve gotten that from the beginning.
Reviewed on Mar 21, 2026
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