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Hotels near Little Italy

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $164 per night from Jan 25 to Jan 26
CA $164
CA $189 total
Jan 25 - Jan 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
Beautiful views from room 248! Great service throughout our stay from all the departments! Quiet, serenely quiet which we really enjoyed. Everything was clean, spacious, kept up and easy to navigate.

Reviewed on Jan 6, 2026

Opens in a new windowBay Club Hotel & Marina
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $153 per night from Jan 22 to Jan 23
CA $153
CA $177 total
Jan 22 - Jan 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Everything was great. Only thing is smelled like an old person 😂

Reviewed on Jan 2, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $187 per night from Jan 19 to Jan 20
CA $187
CA $216 total
Jan 19 - Jan 20
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
The big surprise is the Saturday farmers market right around the corner—such a great location!

Reviewed on Jan 2, 2026

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
Urban Boutique Hotel

Urban Boutique Hotel

3 out of 5
1654 Columbia Street San Diego CA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff and ...
Yes

Reviewed on Jan 4, 2026

Opens in a new windowUrban Boutique Hotel
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $233 per night from Jan 9 to Jan 10
CA $233
CA $329 total
Jan 9 - Jan 10
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
Bernard was very helpful and made my wife & my vacation extra memorable!

Reviewed on Jan 4, 2026

Opens in a new windowSheraton San Diego Resort
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $165 per night from Jan 25 to Jan 26
CA $165
CA $190 total
Jan 25 - Jan 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful ...
It was ok.

Reviewed on Jan 2, 2026

Opens in a new windowDoubleTree by Hilton Hotel San Diego - Mission Valley
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

2.5 out of 5
San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $147 per night from Jan 21 to Jan 22
CA $147
CA $171 total
Jan 21 - Jan 22
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the helpful ...
everything

Reviewed on Jan 5, 2026

Opens in a new windowHampton Inn San Diego-Downtown
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $169 per night from Jan 15 to Jan 16
CA $169
CA $194 total
Jan 15 - Jan 16
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Clean, comfortable room. Reasonable price considering location!

Reviewed on Jan 4, 2026

Opens in a new windowHilton San Diego Mission Valley
Hotel Zindel

Hotel Zindel

2 out of 5
505 W Grape St San Diego CA
Fully refundableReserve now, pay when you stay
Stay at this hotel in San Diego. Enjoy Netflix, hydromassage showerheads, and an in-room coffeemaker. Popular attractions Port of San Diego and San Diego Zoo ...
The best

Reviewed on Dec 3, 2025

Opens in a new windowHotel Zindel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Little Italy Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Little Italy area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Little Italy to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Little Italy are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.