
Book Cheap Spirit Airlines flight from Indianapolis (IND) to San Diego (SAN) from CA $317
Find The Best Day to Book a Cheap Spirit Airlines Flights From Indianapolis to San Diego
Cheapest Spirit Airlines Flights from Indianapolis (IND) to San Diego (SAN)
The cheapest flights to San Diego Intl. found within the past 7 days were CA $855 round trip and CA $317 one way. Prices and availability subject to change. Additional terms may apply.
IND
Indianapolis
SAN
San Diego
CA $855 Roundtrip, found 20 hours ago
CA $855
Roundtrip
found 20 hours ago
IND
Indianapolis
SAN
San Diego
CA $869 Roundtrip, found 20 hours ago
CA $869
Roundtrip
found 20 hours ago
IND
Indianapolis
SAN
San Diego
CA $873 Roundtrip, found 20 hours ago
CA $873
Roundtrip
found 20 hours ago
IND
Indianapolis
SAN
San Diego
CA $887 Roundtrip, found 20 hours ago
CA $887
Roundtrip
found 20 hours ago
IND
Indianapolis
SAN
San Diego
CA $901 Roundtrip, found 20 hours ago
CA $901
Roundtrip
found 20 hours ago
IND
Indianapolis
SAN
San Diego
CA $1,022 Roundtrip, found 20 hours ago
CA $1,022
Roundtrip
found 20 hours ago
IND
Indianapolis
SAN
San Diego
CA $1,035 Roundtrip, found 20 hours ago
CA $1,035
Roundtrip
found 20 hours ago
IND
Indianapolis
SAN
San Diego
CA $1,040 Roundtrip, found 20 hours ago
CA $1,040
Roundtrip
found 20 hours ago
IND
Indianapolis
SAN
San Diego
CA $1,053 Roundtrip, found 20 hours ago
CA $1,053
Roundtrip
found 20 hours ago
Airport code | Country | Airport name | Number of flights |
---|---|---|---|
DTW | USA | Detroit Metropolitan Wayne County | 7 |
FLL | USA | Fort Lauderdale - Hollywood Intl. | 7 |
MCO | USA | Orlando Intl. | 6 |
LAS | USA | McCarran Intl. | 6 |
ORD | USA | O'Hare Intl. | 6 |
IAH | USA | George Bush Intercontinental | 4 |
DFW | USA | Dallas-Fort Worth Intl. | 4 |
LAX | USA | Los Angeles Intl. | 3 |
SJU | PRI | Luis Munoz Marin Intl. | 3 |
PHL | USA | Philadelphia Intl. | 2 |
Travelers ❤️ these 🏨 after their flight to San Diego

Sheraton San Diego Resort
1380 Harbor Island Dr, San Diego, CA
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
8/10 Very Good! (2,713 reviews)
"Excellent stay. Staff upgraded us to a suite complimentary and took care of parking."
Reviewed on Jun. 15, 2025

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,780 reviews)
"Recently renovated room with great view. & great lighting in the room. Did not like: Self parking was too expensive at $49/night & unable to watch local Padre game in room."
Reviewed on Jun. 12, 2025

Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in ...
9/10 Wonderful! (1,706 reviews)
"Love this hotel, great customer service and location!"
Reviewed on Jun. 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Want more than a(n) Spirit Airlines Flight from Indianapolis to San Diego?
Popular Spirit Airlines Flight Routes from IND
Domestic
- Detroit to Austin (DTW - AUS)
- Detroit to Newark Liberty Intl. Airport (DTW - EWR)
- Detroit to Dallas (DTW - DFW)
- Detroit to Tampa (DTW - TPA)
- Detroit to Newark Liberty Intl. Airport (DTW - EWR)
- Newark Liberty Intl. Airport to Fort Lauderdale (EWR - FLL)
- Detroit to Los Angeles (DTW - LAX)
- Detroit to Nashville (DTW - BNA)
- Detroit to Las Vegas (DTW - LAS)
- Detroit to Cancun (DTW - CUN)
International
- Detroit to Las Vegas (DTW - LAS)
- Detroit to Cancun (DTW - CUN)
- Detroit to Miami (DTW - MIA)
- Detroit to Los Angeles (DTW - LAX)
- Seattle to Newark Liberty Intl. Airport (SEA - EWR)
- Detroit to Orlando (DTW - MCO)
- Detroit to Austin (DTW - AUS)
- Detroit to Cancun (DTW - CUN)
- Detroit to Nashville (DTW - BNA)
- Detroit to Fort Lauderdale (DTW - FLL)
Most Popular
Flights
Edmonton to Orange County (YEG - SNA)Vancouver to Palm Springs (YVR - PSP)Vancouver to Las Vegas (YVR - LAS)Detroit to Dallas (DTW - DFW)Edmonton to Los Angeles (YEG - LAX)Montreal to Fort Lauderdale (YUL - FLL)Toronto to Los Angeles (YYZ - LAX)Toronto to San Francisco (YYZ - SFO)Fort Lauderdale to Toronto (FLL - YYZ)Vancouver to San Francisco (YVR - SFO)Vancouver to San Diego (YVR - SAN)Detroit to Myrtle Beach (DTW - MYR)Los Angeles to Vancouver (LAX - YVR)Toronto to Seattle (YYZ - SEA)Toronto to Orange County (YYZ - SNA)Toronto to Dallas (YYZ - DFW)Air Canada Toronto (YYZ) to Myrtle Beach (MYR) flightsSpirit Airlines Niagara Falls (IAG) to Myrtle Beach (MYR) flightsJetBlue Airways Buffalo (BUF) to Fort Lauderdale (FLL) flightsPorter Airlines Toronto (YTZ) to Philadelphia (PHL) flightsWestJet Edmonton (YEG) to Las Vegas (LAS) flightsVancouver to Los Angeles (YVR - LAX)Toronto to Philadelphia (YYZ - PHL)Victoria to Los Angeles (YYJ - LAX)Calgary to San Francisco (YYC - SFO)Air Canada Toronto (YYZ) to Fort Lauderdale (FLL) flightsVancouver to Orange County (YVR - SNA)Toronto to Las Vegas (YYZ - LAS)Swoop Abbotsford (YXX) to Las Vegas (LAS) flightsSeattle to Delhi (SEA - DEL)