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Featured Neptune Beach 4 Star hotels

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $290 per night from Mar 24 to Mar 25
CA $290
CA $332 total
Mar 24 - Mar 25
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,503 reviews)
Clean room, great and friendly staff. Nice amenities

Reviewed on Feb 27, 2026

Opens in a new windowHyatt Regency Jacksonville
DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport

4 out of 5
2101 Dixie Clipper Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $146 per night from Mar 30 to Mar 31
CA $146
CA $166 total
Mar 30 - Mar 31
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
8.4/10 Very Good! (1,733 reviews)
Awesome staff Anne was so sweet and helpful and kind

Reviewed on Feb 25, 2026

Opens in a new windowDoubleTree by Hilton Hotel Jacksonville Airport
DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront

4 out of 5
1201 Riverplace Boulevard Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $140 per night from Mar 29 to Mar 30
CA $140
CA $159 total
Mar 29 - Mar 30
includes taxes & fees
Stay at this hotel in Jacksonville. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. Popular ...
6.8/10 (1,589 reviews)
Overall, very nice. Hot water doesn’t last long.

Reviewed on Feb 23, 2026

Opens in a new windowDoubleTree by Hilton Hotel Jacksonville Riverfront
Marriott Jacksonville Downtown

Marriott Jacksonville Downtown

4 out of 5
245 Water St Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $312 per night from Mar 19 to Mar 20
CA $312
CA $354 total
Mar 19 - Mar 20
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in ...
8.4/10 Very Good! (1,001 reviews)
Room was very clean and the staff was outstanding.

Reviewed on Feb 25, 2026

Opens in a new windowMarriott Jacksonville Downtown
Delta Hotels by Marriott™ Jacksonville Deerwood

Delta Hotels by Marriott™ Jacksonville Deerwood

4 out of 5
4700 Salisbury Rd Jacksonville FL
Fully refundable
The price is CA $148 per night from Mar 22 to Mar 23
CA $148
CA $167 total
Mar 22 - Mar 23
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free parking, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful ...
8.6/10 Excellent! (545 reviews)
Charged card for room that I didn't stay in... Canceled reservation prior to and was illegally charged

Reviewed on Feb 24, 2026

Opens in a new windowDelta Hotels by Marriott™ Jacksonville Deerwood
Omni Amelia Island Resort & Spa

Omni Amelia Island Resort & Spa

4 out of 5
39 Beach Lagoon Road Fernandina Beach FL
Fully refundableReserve now, pay when you stay
The price is CA $382 per night from Mar 4 to Mar 5
CA $382
CA $490 total
Mar 4 - Mar 5
includes taxes & fees
Book a stay at this beach resort in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
Amazing location, property, service and value for money

Reviewed on Feb 15, 2026

Opens in a new windowOmni Amelia Island Resort & Spa
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

4.5 out of 5
4745 Transformation Way Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $268 per night from Mar 21 to Mar 22
CA $268
CA $304 total
Mar 21 - Mar 22
includes taxes & fees
Book a stay at this luxury hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions St. Johns Town Center and TPC ...
9.4/10 Exceptional! (157 reviews)
Ants in the room had to switch room at 11:00

Reviewed on Feb 27, 2026

Opens in a new windowHilton Jacksonville At Mayo Clinic
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

4 out of 5
10605 Deerwood Park Blvd Jacksonville FL
The price is CA $185 per night from Mar 20 to Mar 21
CA $185
CA $210 total
Mar 20 - Mar 21
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,001 reviews)
It was great

Reviewed on Feb 26, 2026

Opens in a new windowSheraton Jacksonville Hotel
Sawgrass Marriott Golf Resort & Spa

Sawgrass Marriott Golf Resort & Spa

4 out of 5
1000 TPC Blvd, Ponte Vedra Beach FL
Fully refundableReserve now, pay when you stay
The price is CA $324 per night from Mar 5 to Mar 6
CA $324
CA $400 total
Mar 5 - Mar 6
includes taxes & fees
Book a stay at this beach resort in Ponte Vedra Beach. Enjoy 5 outdoor pools, a full-service spa, and 9 restaurants. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (1,000 reviews)
The quality of the hotel—room, public spaces, service—did not match the price.

Reviewed on Feb 19, 2026

Opens in a new windowSawgrass Marriott Golf Resort & Spa
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
8 Amelia Village Circle, Amelia Island Fernandina Beach FL
Book a stay at this beach vacation home in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in ...
8.4/10 Very Good! (1,160 reviews)
Love the resort but the room we stayed in had very poor water pressure and the tub backed ip

Reviewed on Feb 24, 2026

Opens in a new windowThe Villas of Amelia Island
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4 Star Hotels Neptune Beach

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Neptune Beach 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Neptune Beach will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Neptune Beach, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Neptune Beach hotel reviews by fellow wanderers