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Featured Palermo 4 Star hotels

Astoria Palace Hotel

Astoria Palace Hotel

4 out of 5
Via Montepellegrino 62, Palermo, PA
Fully refundableReserve now, pay when you stay
Stay at this 4-star business-friendly hotel in Palermo. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (994 reviews)
Stayed for 5 nights. Excellent service and helpful pleasant staff. Comfortable large clean lobby. Rooms cleaned and towels changed punctually everyday. Excellent breakfast. Very convenient location for going in any direction. The fastest elevators !

Reviewed on Sep 21, 2025

Opens in a new windowAstoria Palace Hotel
Hotel Politeama

Hotel Politeama

4 out of 5
Piazza Ruggiero Settimo,15, Palermo, PA
Fully refundableReserve now, pay when you stay
The price is CA $149 per night from Dec 8 to Dec 9
CA $149
CA $179 total
Dec 8 - Dec 9
includes taxes & fees
Stay at this 4-star business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (477 reviews)
Excellent location.

Reviewed on Nov 6, 2025

Opens in a new windowHotel Politeama
San Paolo Palace Hotel

San Paolo Palace Hotel

4 out of 5
Via Messina Marine, 91, Palermo, PA
Fully refundableReserve now, pay when you stay
The price is CA $145 per night from Nov 14 to Nov 15
CA $145
CA $174 total
Nov 14 - Nov 15
includes taxes & fees
Stay at this 4-star business-friendly hotel in Palermo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (707 reviews)
Easy to check in, quiet location, friendly staff

Reviewed on Oct 10, 2025

Opens in a new windowSan Paolo Palace Hotel
Casena Dei Colli, Sure Hotel Collection by Best Western

Casena Dei Colli, Sure Hotel Collection by Best Western

4 out of 5
Via Villa Rosato 20-22, Palermo, PA
Fully refundableReserve now, pay when you stay
The price is CA $82 per night from Dec 7 to Dec 8
CA $82
CA $105 total
Dec 7 - Dec 8
includes taxes & fees
Stay at this 4-star business-friendly hotel in Palermo. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Palermo Harbour and Mondello ...
8/10 Very Good! (869 reviews)
The breakfast the next day was outstanding. So much to choose from

Reviewed on Sep 1, 2025

Opens in a new windowCasena Dei Colli, Sure Hotel Collection by Best Western
President Hotel Palermo

President Hotel Palermo

4 out of 5
Via Francesco Crispi 230, Palermo, PA
Fully refundableReserve now, pay when you stay
The price is CA $83 per night from Nov 23 to Nov 24
CA $83
CA $138 total
Nov 23 - Nov 24
includes taxes & fees
Stay at this 4-star business-friendly hotel in Palermo. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Palermo Harbour and ...
8/10 Very Good! (561 reviews)
Great views, excellent for getting around, close to all amenities- staff very accommodating.

Reviewed on Aug 14, 2025

Opens in a new windowPresident Hotel Palermo
Eurostars Centrale Palace

Eurostars Centrale Palace

4 out of 5
Via Vittorio Emanuele, 327, Palermo, PA
Fully refundableReserve now, pay when you stay
The price is CA $109 per night from Dec 14 to Dec 15
CA $109
CA $134 total
Dec 14 - Dec 15
includes taxes & fees
Stay at this 4-star luxury hotel in Palermo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (973 reviews)
Room clean and great service..

Reviewed on Nov 6, 2025

Opens in a new windowEurostars Centrale Palace
NH Palermo

NH Palermo

4 out of 5
Foro Italico, Palermo, PA
Fully refundableReserve now, pay when you stay
The price is CA $99 per night from Dec 8 to Dec 9
CA $99
CA $123 total
Dec 8 - Dec 9
includes taxes & fees
Stay at this 4-star hotel in Palermo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
8/10 Very Good! (972 reviews)
Fantastic hotel, great staff , great pool , great stay !!

Reviewed on Oct 5, 2025

Opens in a new windowNH Palermo
Mercure Hotel Palermo Centro

Mercure Hotel Palermo Centro

4 out of 5
Via Stabile Mariano 112, Palermo, PA
Fully refundableReserve now, pay when you stay
The price is CA $72 per night from Dec 8 to Dec 9
CA $72
CA $94 total
Dec 8 - Dec 9
includes taxes & fees
Stay at this 4-star business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (970 reviews)
It’s close to the port . The breakfast is very good. I will book it again if I have a chance come to Palermo next time.

Reviewed on Oct 21, 2025

Opens in a new windowMercure Hotel Palermo Centro
Palazzo Natoli Boutique Hotel

Palazzo Natoli Boutique Hotel

4 out of 5
Via Santissimo Salvatore 6, Palermo, PA
The price is CA $306 per night from Nov 28 to Nov 29
CA $306
CA $351 total
Nov 28 - Nov 29
includes taxes & fees
Stay at this 4-star business-friendly hotel in Palermo. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (432 reviews)
A refreshing change from the larger hotels we have frequented. No crowded buffet breakfast….at each breakfast you selection your next day’s breakfast. No bar or gym so if you are looking for this understand that is not one of the amenities. Staff was extremely helpful in planning a trip to Monte ...

Reviewed on Nov 3, 2025

Opens in a new windowPalazzo Natoli Boutique Hotel
Splendid Hotel La Torre

Splendid Hotel La Torre

4 out of 5
Via Piano Gallo 11, Palermo, PA
Fully refundableReserve now, pay when you stay
The price is CA $155 per night from Nov 17 to Nov 18
CA $155
CA $186 total
Nov 17 - Nov 18
includes taxes & fees
Stay at this 4-star business-friendly hotel in Palermo. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
7.6/10 Good! (464 reviews)
The location was perfect. At the end of Mondello with stunning views. Many pools and cute little rock beach to jump in the ocean. Rooms were ok too. The only thing was that the property needs maintenance and updating. The climb to "torre" is dangerous and they really should not allow anyone going ...

Reviewed on Nov 3, 2025

Opens in a new windowSplendid Hotel La Torre
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4 Star Hotels Palermo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Palermo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Palermo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Palermo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Palermo hotel reviews by fellow wanderers