Find and compare 4 Star hotels in Palermo

Name: Mercure Hotel Palermo Centro
Price range: CA $115

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Featured Palermo 4 Star hotels

Astoria Palace Hotel

Via Montepellegrino 62 Palermo PA

Fully refundableReserve now, pay when you stay

CA $98

CA $123 total

Nov 1 - Nov 2

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...

7.2/10 Good! (1,000 reviews)

"It would be nice to have tea, coffe, or hot chocolate making facilities in the room."

Reviewed on Sep 5, 2026

Grand Hotel Piazza Borsa

Via dei Cartari 18 Palermo PA

Fully refundableReserve now, pay when you stay

CA $228

CA $265 total

Nov 1 - Nov 2

includes taxes & fees

Book a stay at this spa hotel in Palermo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms in ...

9/10 Wonderful! (986 reviews)

Reviewed on Oct 3, 2026

Hotel Politeama

Piazza Ruggiero Settimo,15 Palermo PA

Fully refundableReserve now, pay when you stay

CA $153

CA $183 total

Nov 3 - Nov 4

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...

9.4/10 Exceptional! (671 reviews)

"I love the nicely cooked tasty vegetables for the breakfast. The room is spacious abs clean."

Reviewed on Oct 1, 2026

President Hotel Palermo

Via Francesco Crispi 230 Palermo PA

Fully refundableReserve now, pay when you stay

CA $139

CA $168 total

Nov 1 - Nov 2

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Mondello Beach and ...

8.2/10 Very good! (640 reviews)

"Hotel was nice, and provided a place to see most of downtown Palermo. Breakfast was typical Italian buffet."

Reviewed on Sep 27, 2026

Eurostars Centrale Palace

Via Vittorio Emanuele, 327 Palermo PA

Fully refundableReserve now, pay when you stay

CA $180

CA $212 total

Nov 2 - Nov 3

includes taxes & fees

Book a stay at this luxury hotel in Palermo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...

8.4/10 Very good! (1,001 reviews)

"A great place to stay. Right at the heart of Palermo. Two issues- last few hundred meters have to walk with luggage as they don’t allow car there. Second parking is an issue here- need to park at a nearby garage."

Reviewed on Oct 3, 2026

Quintocanto Hotel and Spa

Corso Vittorio Emanuele, 310 Palermo PA

Fully refundableReserve now, pay when you stay

CA $175

CA $206 total

Nov 3 - Nov 4

includes taxes & fees

Book a stay at this spa hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...

8.4/10 Very good! (553 reviews)

"The hotel was pleasant enough. Charming old building, decent room, very nice courtyard for breakfast and dinner. One complaint, we booked a taxi from the airport to the hotel through the hotel. When our flight was delayed and we missed our connection we messaged the hotel well in advance to let them ..."

Reviewed on Sep 23, 2026

San Paolo Palace Hotel

Via Messina Marine, 91 Palermo PA

Fully refundableReserve now, pay when you stay

CA $119

CA $146 total

Nov 1 - Nov 2

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.4/10 Good! (788 reviews)

"Good, clean hotel but not updated. Not a very nice location: you have to walk/drive around 10/12 blocks through a not nice neighborhood to get to a street where there is restaurants and shopping. There is a restaurant in the hotel, but we did not use it. Breakfast was ok. Has a nice view from the ..."

Reviewed on Oct 2, 2026

Cristal Hotel Palermo

Via Roma 477 A Palermo PA

Fully refundableReserve now, pay when you stay

CA $122

CA $149 total

Nov 2 - Nov 3

includes taxes & fees

Stay at this hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Mondello Beach and Teatro Massimo are located ...

8.2/10 Very good! (847 reviews)

"Initial impression when entering to find an actual desk with PCs on it inside the door rather than an actual check in reception desk was a bit of a shock for 4* establishment. Reception staff very nice, friendly and helpful. Nice to have water at reception area - not there later on at night. Room ..."

Reviewed on Sep 24, 2026

NH Palermo

Foro Italico Palermo PA

Fully refundableReserve now, pay when you stay

CA $191

CA $225 total

Nov 3 - Nov 4

includes taxes & fees

Stay at this hotel in Palermo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...

Mercure Hotel Palermo Centro

Via Stabile Mariano 112 Palermo PA

Fully refundableReserve now, pay when you stay

CA $115

CA $141 total

Nov 2 - Nov 3

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...

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4 Star Hotels Palermo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Palermo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Palermo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Palermo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Palermo hotel reviews by fellow wanderers

Grand Hotel Piazza Borsa

5 out of 5

Posted 2 hours ago

Travelocity Verified Review

"If you are looking for old-world charm, this fabulous hotel has it in spades. This is every bit a 5 star hotel. The rooms are spacious, beautifully decorated, and the staff is impeccable. Attention to detail is the rule. Breakfast was fabulous and the lobby is a wonderful place to relax and have a drink after a night out. At first the neighborhood seemed a bit on the gritty side, but that seems to be much less of an issue after we got the hang of things and were more comfortable. We think this hotel is awesome."

A verified traveller stayed at Grand Hotel Piazza Borsa