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Featured Palermo 4 Star hotels

Hotel Politeama

Hotel Politeama

4 out of 5
Piazza Ruggiero Settimo,15 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $164 per night from Mar 4 to Mar 5
CA $164
CA $194 total
Mar 4 - Mar 5
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (497 reviews)
Great central location. Modern, clean, superb breakfast options. Polite and helpful staff. Some noise outside, but you are in the city centre after all. Unusual pillows, you’ll see what I mean when you go. But do stay here as we would definitely go back.

Reviewed on Feb 3, 2026

Opens in a new windowHotel Politeama
San Paolo Palace Hotel

San Paolo Palace Hotel

4 out of 5
Via Messina Marine, 91 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $120 per night from Mar 14 to Mar 15
CA $120
CA $146 total
Mar 14 - Mar 15
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (712 reviews)
Easy to check in, quiet location, friendly staff

Reviewed on Oct 10, 2025

Opens in a new windowSan Paolo Palace Hotel
Eurostars Centrale Palace

Eurostars Centrale Palace

4 out of 5
Via Vittorio Emanuele, 327 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $186 per night from Feb 25 to Feb 26
CA $186
CA $219 total
Feb 25 - Feb 26
includes taxes & fees
Book a stay at this luxury hotel in Palermo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (973 reviews)
The room was clean, quiet and comfortable. Breakfast was good, and always had hot water for showers. Also good servce.

Reviewed on Jan 20, 2026

Opens in a new windowEurostars Centrale Palace
Astoria Palace Hotel

Astoria Palace Hotel

4 out of 5
Via Montepellegrino 62 Palermo PA
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (996 reviews)
Stayed for 5 nights. Excellent service and helpful pleasant staff. Comfortable large clean lobby. Rooms cleaned and towels changed punctually everyday. Excellent breakfast. Very convenient location for going in any direction. The fastest elevators !

Reviewed on Sep 21, 2025

Opens in a new windowAstoria Palace Hotel
Ibis Styles Palermo Cristal

Ibis Styles Palermo Cristal

4 out of 5
Via Roma 477 A Palermo PA
The price is CA $118 per night from Mar 15 to Mar 16
CA $118
CA $144 total
Mar 15 - Mar 16
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Teatro Massimo and Palermo ...
8/10 Very Good! (778 reviews)
The location was good and the breakfast was excellent. Housekeeping made the bed every day, but the towels weren’t replaced with new ones.

Reviewed on Nov 6, 2025

Opens in a new windowIbis Styles Palermo Cristal
Mercure Hotel Palermo Centro

Mercure Hotel Palermo Centro

4 out of 5
Via Stabile Mariano 112 Palermo PA
The price is CA $87 per night from Feb 22 to Feb 23
CA $87
CA $110 total
Feb 22 - Feb 23
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (969 reviews)
Excellent breakfast. The room is spacious with a big balcony and great city view.

Reviewed on Jan 20, 2026

Opens in a new windowMercure Hotel Palermo Centro
President Hotel Palermo

President Hotel Palermo

4 out of 5
Via Francesco Crispi 230 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $88 per night from Mar 1 to Mar 2
CA $88
CA $143 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Palermo Harbour and ...
8/10 Very Good! (569 reviews)
Clean and spacious room, location, pleasant staff, great check in and delicious breakfast buffet.

Reviewed on Dec 22, 2025

Opens in a new windowPresident Hotel Palermo
Hotel Plaza Opera

Hotel Plaza Opera

4 out of 5
Via Gallo Nicolo' 2 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $159 per night from Feb 25 to Feb 26
CA $159
CA $190 total
Feb 25 - Feb 26
includes taxes & fees
Book a stay at this spa hotel in Palermo. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (597 reviews)
We did not eat breakfast

Reviewed on Jan 3, 2026

Opens in a new windowHotel Plaza Opera
Casena Dei Colli, Sure Hotel Collection by Best Western

Casena Dei Colli, Sure Hotel Collection by Best Western

4 out of 5
Via Villa Rosato 20-22 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $91 per night from Feb 15 to Feb 16
CA $91
CA $115 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Palermo Harbour and Mondello ...
8/10 Very Good! (877 reviews)
I stayed one night in Palermo, and since it’s almost impossible to find a hotel with parking in the city center, this hotel was a great find. It offers free parking, which is a huge advantage. The rooms are large and comfortable, the price is very affordable, and the reception staff is warm and friendly. ...

Reviewed on Jan 23, 2026

Opens in a new windowCasena Dei Colli, Sure Hotel Collection by Best Western
Palazzo Natoli Boutique Hotel

Palazzo Natoli Boutique Hotel

4 out of 5
Via Santissimo Salvatore 6 Palermo PA
The price is CA $330 per night from Feb 20 to Feb 21
CA $330
CA $378 total
Feb 20 - Feb 21
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (449 reviews)
Spacious room in an excellent and accessible area of Palermo. Guest services were very helpful. All around a positive experience.

Reviewed on Feb 5, 2026

Opens in a new windowPalazzo Natoli Boutique Hotel
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4 Star Hotels Palermo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Palermo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Palermo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Palermo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Palermo hotel reviews by fellow wanderers