Find and compare 4 Star hotels in Palermo

Name: Palazzo Natoli Boutique Hotel
Rating: 9.8

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Featured Palermo 4 Star hotels

Hotel Politeama

Piazza Ruggiero Settimo,15 Palermo PA

Fully refundableReserve now, pay when you stay

CA $140

CA $169 total

Jan 17 - Jan 18, 2026

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...

9.2/10 Wonderful! (489 reviews)

This is a nice hotel with some pros and cons. Pros: Good location close to good bakeries, coffee shops, shopping, and theaters. It's a fairly long walk to the Kalsa and Cattedrale, so not so convenient if you want to focus your sightseeing on those areas. The hotel is clean and the rooms are modern ...

Reviewed on Dec 11, 2025

San Paolo Palace Hotel

Via Messina Marine, 91 Palermo PA

Fully refundableReserve now, pay when you stay

CA $111

CA $137 total

Jan 7 - Jan 8, 2026

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.2/10 Good! (711 reviews)

Easy to check in, quiet location, friendly staff

Reviewed on Oct 10, 2025

Eurostars Centrale Palace

Via Vittorio Emanuele, 327 Palermo PA

Fully refundableReserve now, pay when you stay

CA $167

CA $198 total

Jan 28 - Jan 29, 2026

includes taxes & fees

Book a stay at this luxury hotel in Palermo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...

8.4/10 Very Good! (973 reviews)

Stuff was very helpful.

Reviewed on Dec 9, 2025

Astoria Palace Hotel

Via Montepellegrino 62 Palermo PA

Fully refundableReserve now, pay when you stay

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...

7.2/10 Good! (994 reviews)

Stayed for 5 nights. Excellent service and helpful pleasant staff. Comfortable large clean lobby. Rooms cleaned and towels changed punctually everyday. Excellent breakfast. Very convenient location for going in any direction. The fastest elevators !

Reviewed on Sep 21, 2025

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Ibis Styles Palermo Cristal

Via Roma 477 A Palermo PA

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Teatro Massimo and Palermo ...

8/10 Very Good! (776 reviews)

The location was good and the breakfast was excellent. Housekeeping made the bed every day, but the towels weren’t replaced with new ones.

Reviewed on Nov 6, 2025

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Mercure Hotel Palermo Centro

Via Stabile Mariano 112 Palermo PA

Fully refundableReserve now, pay when you stay

CA $79

CA $101 total

Jan 6 - Jan 7, 2026

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...

8.2/10 Very Good! (969 reviews)

Friendly and helpful staff, fantastic breakfast good to have a balcony

Reviewed on Nov 29, 2025

President Hotel Palermo

Via Francesco Crispi 230 Palermo PA

Fully refundableReserve now, pay when you stay

CA $89

CA $145 total

Jan 23 - Jan 24, 2026

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Palermo Harbour and ...

8/10 Very Good! (565 reviews)

Clean and spacious room, location, pleasant staff, great check in and delicious breakfast buffet.

Reviewed on Dec 22, 2025

Hotel Plaza Opera

Via Gallo Nicolo' 2 Palermo PA

Fully refundableReserve now, pay when you stay

CA $155

CA $186 total

Jan 3 - Jan 4, 2026

includes taxes & fees

Book a stay at this spa hotel in Palermo. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...

8.4/10 Very Good! (588 reviews)

The only problem was that the jacuzzi was booked the entire weekend and we were not able to use it which sucks. After that was the main reason to book the hotel. None of the spa services were available because over booked. They should alert when you make the reservation.

Reviewed on Nov 15, 2025

Casena Dei Colli, Sure Hotel Collection by Best Western

Via Villa Rosato 20-22 Palermo PA

Fully refundableReserve now, pay when you stay

CA $70

CA $91 total

Jan 18 - Jan 19, 2026

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Palermo Harbour and Mondello ...

8/10 Very Good! (874 reviews)

The breakfast the next day was outstanding. So much to choose from

Reviewed on Sep 1, 2025

Palazzo Natoli Boutique Hotel

Via Santissimo Salvatore 6 Palermo PA

Book a stay at this business-friendly hotel in Palermo. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff ...

9.8/10 Exceptional! (441 reviews)

Staff & location great. We were in the Family room in the Annex. I loved it but my partner wished it had more windows.

Reviewed on Dec 21, 2025

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4 Star Hotels Palermo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Palermo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Palermo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Palermo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.