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Featured Mestre 5 Star hotels

Hilton Molino Stucky Venice

Hilton Molino Stucky Venice

5 out of 5
Isola Della Giudecca 810 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $336 per night from Mar 31 to Apr 1
CA $336
CA $386 total
Mar 31 - Apr 1
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy an outdoor pool, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,000 reviews)
Great location

Reviewed on Mar 24, 2026

Opens in a new windowHilton Molino Stucky Venice
The St. Regis Venice

The St. Regis Venice

5 out of 5
Campo Barozzi Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $1,765 per night from Mar 30 to Mar 31
CA $1,765
CA $1,958 total
Mar 30 - Mar 31
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (120 reviews)
Hotel was amazing! Great location, clean, friendly staff, very helpful. Hotel felt like home.

Reviewed on Feb 16, 2026

Opens in a new windowThe St. Regis Venice
NH Collection Venezia Grand Hotel Dei Dogi

NH Collection Venezia Grand Hotel Dei Dogi

5 out of 5
Fondamenta Madonna Dell'Orto 3500 Venice VE
The price is CA $517 per night from Apr 7 to Apr 8
CA $517
CA $584 total
Apr 7 - Apr 8
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy breakfast (surcharge), room service, and a 24-hour front desk. Our guests praise the helpful staff and the ...
9/10 Wonderful! (491 reviews)
Fantastic service and location. Loved it all.

Reviewed on Mar 24, 2026

Opens in a new windowNH Collection Venezia Grand Hotel Dei Dogi
Baglioni Hotel Luna - The Leading Hotels of the World

Baglioni Hotel Luna - The Leading Hotels of the World

5 out of 5
San Marco, 1243 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $942 per night from Apr 15 to Apr 16
CA $942
CA $1,052 total
Apr 15 - Apr 16
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (1,001 reviews)
Beautiful hotel, wonderful location, lovely atmosphere. Truly memorable.

Reviewed on Mar 24, 2026

Opens in a new windowBaglioni Hotel Luna - The Leading Hotels of the World
The Venice Venice Hotel

The Venice Venice Hotel

5 out of 5
Sestiere Cannaregio 5631 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $1,118 per night from Mar 26 to Mar 27
CA $1,118
CA $1,246 total
Mar 26 - Mar 27
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a 24-hour fitness center, and onsite spa services. Our guests praise the helpful staff in our reviews. ...
9.8/10 Exceptional! (105 reviews)
Always unbelievable. Love this treat.

Reviewed on Feb 14, 2026

Opens in a new windowThe Venice Venice Hotel
Radisson Collection Hotel, Palazzo Nani Venice

Radisson Collection Hotel, Palazzo Nani Venice

5 out of 5
Fondamenta Cannaregio 1105 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $517 per night from Mar 31 to Apr 1
CA $517
CA $585 total
Mar 31 - Apr 1
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy breakfast (surcharge), a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in ...
9.8/10 Exceptional! (179 reviews)
Great service, good breakfast buffet selection plus complementary dish from the a la carte menu. Comfortable beds and spacious rooms but not very sound proof.

Reviewed on Feb 1, 2026

Opens in a new windowRadisson Collection Hotel, Palazzo Nani Venice
The Gritti Palace, a Luxury Collection Hotel, Venice

The Gritti Palace, a Luxury Collection Hotel, Venice

5 out of 5
Campo Santa Maria Del Giglio O Zobenigo Venice VE
The price is CA $2,550 per night from Apr 12 to Apr 13
CA $2,550
CA $2,821 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Popular attractions Grand Canal and St. Mark's Square ...
9.4/10 Exceptional! (241 reviews)
Amazing experience!

Reviewed on Feb 20, 2026

Opens in a new windowThe Gritti Palace, a Luxury Collection Hotel, Venice
Ca' Sagredo

Ca' Sagredo

5 out of 5
Campo Santa Sofia, 4198/99 Ca' D'Oro Venice VE
The price is CA $497 per night from Mar 30 to Mar 31
CA $497
CA $563 total
Mar 30 - Mar 31
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
Opens in a new windowCa' Sagredo
Palazzo Venart Luxury Hotel

Palazzo Venart Luxury Hotel

5 out of 5
Santa Croce 1961 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $876 per night from Mar 31 to Apr 1
CA $876
CA $1,092 total
Mar 31 - Apr 1
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, room service, and a 24-hour front desk. Popular attractions Piazzale Roma and St. Mark's Square ...
9.8/10 Exceptional! (169 reviews)
Beautiful apartment with all the amenities one would need. Also, a quieter part of Venice but close enough to restaurants and shopping

Reviewed on Feb 1, 2026

Opens in a new windowPalazzo Venart Luxury Hotel
Nolinski Venezia - Evok Collection

Nolinski Venezia - Evok Collection

5 out of 5
2032 Calle Larga XXII Marzo Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $1,190 per night from Mar 29 to Mar 30
CA $1,190
CA $1,325 total
Mar 29 - Mar 30
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (109 reviews)
Room was clean and the property is beautiful with some beautiful artworks. Staff was nice and pleasant. The older people working there are amazing, and the young can definitely learn from them. Simon was especially wonderful. When I checked in I was not told about the pool nor did I use it- I would ...

Reviewed on Mar 22, 2026

Opens in a new windowNolinski Venezia - Evok Collection
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Five Star Hotels in Mestre

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Mestre to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Mestre 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Mestre before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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