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Featured Mestre 5 Star hotels

Hilton Molino Stucky Venice

Hilton Molino Stucky Venice

5 out of 5
Isola Della Giudecca 810 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $227 per night from Dec 3 to Dec 4
CA $227
CA $265 total
Dec 3 - Dec 4
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy an outdoor pool, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (1,002 reviews)
Check in was pre

Reviewed on Nov 5, 2025

Opens in a new windowHilton Molino Stucky Venice
The St. Regis Venice

The St. Regis Venice

5 out of 5
Campo Barozzi Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $1,164 per night from Dec 15 to Dec 16
CA $1,164
CA $1,297 total
Dec 15 - Dec 16
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (116 reviews)
Clean hotel great service Very nice staff We will definitely be back Excellent choice

Reviewed on Nov 5, 2025

Opens in a new windowThe St. Regis Venice
The Gritti Palace, a Luxury Collection Hotel, Venice

The Gritti Palace, a Luxury Collection Hotel, Venice

5 out of 5
Campo Santa Maria Del Giglio O Zobenigo Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $1,388 per night from Dec 15 to Dec 16
CA $1,388
CA $1,543 total
Dec 15 - Dec 16
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Popular attractions St. Mark's Square and Piazzale ...
9.4/10 Exceptional! (236 reviews)
Excellent place

Reviewed on Jun 2, 2025

Opens in a new windowThe Gritti Palace, a Luxury Collection Hotel, Venice
NH Collection Venezia Grand Hotel Dei Dogi

NH Collection Venezia Grand Hotel Dei Dogi

5 out of 5
Fondamenta Madonna Dell'Orto 3500 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $309 per night from Dec 2 to Dec 3
CA $309
CA $356 total
Dec 2 - Dec 3
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy breakfast (surcharge), room service, and a 24-hour front desk. Our guests praise the helpful staff and the ...
9/10 Wonderful! (464 reviews)
Great premium option

Reviewed on Oct 16, 2025

Opens in a new windowNH Collection Venezia Grand Hotel Dei Dogi
Radisson Collection Hotel, Palazzo Nani Venice

Radisson Collection Hotel, Palazzo Nani Venice

5 out of 5
Fondamenta Cannaregio 1105 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $444 per night from Dec 15 to Dec 16
CA $444
CA $505 total
Dec 15 - Dec 16
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy breakfast (surcharge), a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff in ...
9.8/10 Exceptional! (160 reviews)
Lovely hotel, great location and staff

Reviewed on Oct 29, 2025

Opens in a new windowRadisson Collection Hotel, Palazzo Nani Venice
The Venice Venice Hotel

The Venice Venice Hotel

5 out of 5
Sestiere Cannaregio 5631 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $718 per night from Dec 6 to Dec 7
CA $718
CA $806 total
Dec 6 - Dec 7
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a 24-hour fitness center, and onsite spa services. Our guests praise the helpful staff in our reviews. ...
9.6/10 Exceptional! (87 reviews)
Great staff

Reviewed on Oct 7, 2025

Opens in a new windowThe Venice Venice Hotel
Baglioni Hotel Luna - The Leading Hotels of the World

Baglioni Hotel Luna - The Leading Hotels of the World

5 out of 5
San Marco, 1243 Venice VE
The price is CA $767 per night from Nov 19 to Nov 20
CA $767
CA $860 total
Nov 19 - Nov 20
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (987 reviews)
We've been to Venice many times and have family there. This is the first time staying at the Baglioni and it did not disappoint. We upgraded to a Suite overlooking the Venetian Lagoon and it was simply amazing. The Breakfast Buffet was great with a wide variety of breakfast fare. We could even order ...

Reviewed on Nov 3, 2025

Opens in a new windowBaglioni Hotel Luna - The Leading Hotels of the World
Nolinski Venezia - Evok Collection

Nolinski Venezia - Evok Collection

5 out of 5
2032 Calle Larga XXII Marzo Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $857 per night from Dec 1 to Dec 2
CA $857
CA $959 total
Dec 1 - Dec 2
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (97 reviews)
Exceptional hotel….

Reviewed on Nov 11, 2025

Opens in a new windowNolinski Venezia - Evok Collection
Ca' Sagredo

Ca' Sagredo

5 out of 5
Campo Santa Sofia, 4198/99 Ca' D'Oro, Venice, VE
Fully refundable
The price is CA $360 per night from Dec 1 to Dec 2
CA $360
CA $413 total
Dec 1 - Dec 2
includes taxes & fees
Stay at this 5-star luxury hotel in Venice. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (458 reviews)
The hotel is GORGEOUS! And the staff is wonderful. Only issue would be that wifi is spotty.

Reviewed on Nov 7, 2025

Opens in a new windowCa' Sagredo
Palazzo Venart Luxury Hotel

Palazzo Venart Luxury Hotel

5 out of 5
Santa Croce 1961 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $840 per night from Dec 2 to Dec 3
CA $840
CA $940 total
Dec 2 - Dec 3
includes taxes & fees
Stay at this property in Venice. Enjoy free WiFi, room service, and a 24-hour front desk. Popular attractions Piazzale Roma and St. Mark's Square are located ...
9.8/10 Exceptional! (164 reviews)
This is without doubt the best hotel I have ever been at. This was my third stay at Palazzo Venart and the quality of the staff and management is OUTSTANDING. The location is marvelous, the rooms splendid, and the atmosphere wonderful. I will definitely go back a fourth and fifth time...

Reviewed on Nov 6, 2025

Opens in a new windowPalazzo Venart Luxury Hotel
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Five Star Hotels in Mestre

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Mestre to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Mestre 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Mestre before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Mestre hotel reviews by fellow wanderers