Find and compare 5 Star hotels in Panama City
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Featured Panama City 5 Star hotels

Hotel Riu Plaza Panama
"Very good property that has a good breakfast buffet. Staff was very nice"
Reviewed on May 22, 2026

Waldorf Astoria Panama
"Excelentes instalaciones y el personal es increíble de lo amable y con ganas de satisfacer tus deseos"
Reviewed on May 18, 2026

Sofitel Legend Casco Viejo, Panama City
"Easily one the best hotel stays ever. Great property. Great food. Excellent service."
Reviewed on May 14, 2026

JW Marriott Panama
"The entire staff were amazing, front desk, cleaning personnel, front door, restaurant staff, everyone in the entire building were nice, professional and informative. I am definitely recommending this hotel for anyone who has the slightest interest."
Reviewed on May 22, 2026

Hyatt Regency Panama City
"Great price on a suite!"
Reviewed on May 20, 2026

W Panama
"We booked the Supreme Room and it was amazing! It had a great view and was very spacious. Upon arrival, the staff was so nice and helpful. They provided us with suggestions on where to go to eat, party and sightsee. They were always available if we had questions too. The location was close to everything ..."
Reviewed on May 4, 2026

The Westin Playa Bonita Panama
"Friendly staff,great accomadations . Very relaxing. I will go back."
Reviewed on May 7, 2026

Hilton Panama
"Very helpful and responsive staff. Quality across the board"
Reviewed on May 20, 2026

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
"Perfect"
Reviewed on May 8, 2026

Renaissance Panama City Hotel
"Breakfast was very good, staff are very helpful and friendly"
Reviewed on May 11, 2026
Five Star Hotels in Panama City
Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Panama City to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Panama City 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Panama City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Panama City hotel reviews by fellow wanderers

Hotel Riu Plaza Panama
"Very good property that has a good breakfast buffet. Staff was very nice"
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