Book luxury hotels in Panama City

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Top Panama City Luxury Hotels

Don't see what you're looking for?
See all available properties in Panama City
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

About Panama City Luxury Hotels

If you’re looking for a luxury vacation in Panama City, with plush bedding, designer toiletries, world-class concierge staff, and access to the best restaurants and spa treatments, Travelocity has everything you need. You can live it up like the rich and famous in a luxury hotel in Panama City with discounts and offerings from Travelocity. Now you can have all the luxury perks you want, and stay on the cheap. So live it up! A luxury hotel in Panama City can whisk you away without breaking the bank.

Panama City hotels essential information

Accommodation
947 hotels
Lowest Price
CA $83
Highest Price
CA $365
Popular hotels
JW Marriott Panama, Bristol Panama, a Registry Collection Hotel, Waldorf Astoria Panama, American Trade Hotel, Sortis Hotel, Spa & Casino, Autograph Collection, Hilton Panama, Las Americas Golden Tower Panama, Marriott Panama Hotel, Metro Hotel Panama, Hotel Riu Plaza Panama, The Westin Playa Bonita Panama, Hospedium Princess Hotel Panama

Recent Panama City hotel reviews by fellow wanderers