Cheap Flight Deals to Sikeston MO from CA $196

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How to find cheap flights to Sikeston?

The cheapest prices found with in the last 7 days for return flights were CA $320 and CA $196 for one-way flights to Sikeston for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel datesFlights from*
DFWSt. LouisJune 12 to June 15CA $320
SEASt. LouisMay 24 to May 31CA $355
ATLSt. LouisJune 14 to June 15CA $918
*Prices include taxes and fees
OriginDestinationTravel datesFlights from*
SEASt. LouisMay 4 to May 11CA $770
*Prices include taxes and fees

Your guide to flights to Sikeston, MO

Alaska Airlines, American Airlines, Delta fly to Sikeston, so use Travelocity to search, find, and compare some truly tempting deals from the 4 airlines—that way you can be sure you’ve found the best deal for you. A flight to Sikeston MO currently costs between CA $320 and CA $918. Prices vary, but for the best fares, travel in May when prices are at their lowest.  

Top tips for finding cheap flights to Sikeston  

The cheapest flight for a round trip to Sikeston is currently CA $320. When you search for flights to Sikeston, enter your preferred travel dates then click on ‘flexible dates’ to compare cheap flight tickets to Sikeston for nearby days.  The cheapest month to travel to Sikeston is May from our list of deals available.  

But if you’re flexible about when you travel, you can find great deals on flights across the year. If you’re planning a vacation, you can save more on Travelocity when you bundle flights with car rental and hotel bookings, too. Many airlines currently offer flexible booking options, so look for flights offering no change fees.   

How to cancel flights to Sikeston 

We know plans change, that’s why at Travelocity, we make it as easy as possible for you to cancel or amend your plane tickets. Go to My Trips, enter your itinerary number, then follow the instructions. Many airlines let you cancel flights online free of charge if you booked it in the last 24 hours. Visit Customer Service for more advice.  

Why you should book your flight to Sikeston with Travelocity 

We have top deals on plane tickets even for last minute flights to Sikeston, so you can simply type in your travel dates and compare our best prices. Booking with Travelocity means you get flexible cancellation options, 24/7 support, and, thanks to our Price Match Promise, if the airfare drops after you book, you can get a refund! Whether you’re planning a business trip, weekend getaway, or a family vacation—let Travelocity get you to Sikeston for less. 

Find The Perfect Hotel For After Your Flight

Amazing Place to Stay After Flight to Sikeston

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
The price is CA $118 per night from May 11 to May 12
CA $118
CA $136 total
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
Quiet, solid building, no noise while sleeping day
"Quiet. Just what I needed for day time sleep."

Reviewed on Apr. 28, 2025

Pear Tree Inn Sikeston
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
The price is CA $100 per night from May 5 to May 6
CA $100
CA $112 total
includes taxes & fees
May 5 - May 6
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,001 reviews)
"Customer services were good however I feel the rates could have been better and the breakfast was a little “cheesy”."

Reviewed on Apr. 25, 2025

Pear Tree Inn Cape Girardeau West
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is CA $112 per night from May 4 to May 5
CA $112
CA $127 total
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"Nice and clean"

Reviewed on Apr. 14, 2025

Days Inn and Suites by Wyndham Sikeston
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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 out of 5
3253 William Street, Cape Girardeau, MO
The price is CA $142 per night from May 11 to May 12
CA $142
CA $161 total
includes taxes & fees
May 11 - May 12
Book a stay at this spa hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,006 reviews)
Return Stay💋
"I chose this hotel because I stayed 8 months ago when I daughter was scheduled for a C-section and I was so happy with the staff, location of the property and condition of the room I had to return."

Reviewed on Apr. 25, 2025

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is CA $112 per night from May 4 to May 5
CA $112
CA $127 total
includes taxes & fees
May 4 - May 5
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"Nice and clean"

Reviewed on Apr. 14, 2025

Days Inn and Suites by Wyndham Sikeston
Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and patios. Popular attractions Riverfront Park and eDen Spa & Salon are located ...
9.8/10 Exceptional! (161 reviews)
Best of the best!
"This upstairs unit is perfect for a long weekend getaway trip! It has everything you need and is in the perfect location to the downtown area. Walking distance to shopping and great restaurants! The area is very safe and my daughter and I are comfortable walking around the downtown area any time ..."

Reviewed on Apr. 7, 2025

Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
The price is CA $81 per night from May 5 to May 6
CA $81
CA $91 total
includes taxes & fees
May 5 - May 6
Stay at this hotel in Cape Girardeau. Enjoy free WiFi, an outdoor pool, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,000 reviews)
"Continental breakfast where the hostess made the waffles for you; friendly staff."

Reviewed on Apr. 23, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
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Quality Inn

Quality Inn

2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
The price is CA $83 per night from May 7 to May 8
CA $83
CA $94 total
includes taxes & fees
May 7 - May 8
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ...
Best Hotel in Cape!!
"My husband and I like to get away sometimes on the weekend and a lot more than not we prefer Quality Inn over others, it is affordable; good location; rooms are nice and cozy, I would like to maybe request a little more hot breakfast."

Reviewed on Apr. 26, 2025

Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Sikeston

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
The price is CA $137 per night from May 11 to May 12
CA $137
CA $157 total
includes taxes & fees
May 11 - May 12
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,002 reviews)
Great Place to Stay
"Great staff. Called you by your name and were super helpful. The room was very spacious and comfortable. The whole property was clean and well maintained. The breakfast was very tasty and ample with a nice attendant making sure everything was available."

Reviewed on Apr. 22, 2025

Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
The price is CA $118 per night from May 11 to May 12
CA $118
CA $136 total
includes taxes & fees
May 11 - May 12
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
Quiet, solid building, no noise while sleeping day
"Quiet. Just what I needed for day time sleep."

Reviewed on Apr. 28, 2025

Pear Tree Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
The price is CA $125 per night from May 11 to May 12
CA $125
CA $142 total
includes taxes & fees
May 11 - May 12
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,004 reviews)
"I did notice that there was something on the outside of the toilet bowl front that needed to be wiped clean, but other than that the room was nice."

Reviewed on Apr. 27, 2025

Best Western Plus Sikeston
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Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
The price is CA $137 per night from May 6 to May 7
CA $137
CA $154 total
includes taxes & fees
May 6 - May 7
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (924 reviews)
"Always The best hotel"

Reviewed on Apr. 27, 2025

Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Sikeston Flight and Hotel Packages

Sikeston flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel
Hilton Garden Inn Chesterfield
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Need a car after flight to Sikeston?

Frequently asked questions

Which airlines fly to Sikeston?
You won’t find many airlines that service Sikeston. So, if you’re planning to embark on your long-anticipated adventure from here, book a seat with Cape Air as soon as you can.
Where to stay in Sikeston
Lock in your Sikeston accommodations through Travelocity and then turn your attention to what really matters — creating remarkable travel memories. Pick from 12 lodgings from which you can explore this enticing destination.If you’re on the hunt for the top accommodation options in Sikeston, we suggest the Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel and the Hampton Inn Sikeston. Reserve a room and then start booking all your exciting getaway activities.
Places to visit in Sikeston
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How to get through airport security fast when traveling to Sikeston
Your adventure to Sikeston starts as soon as you’ve finished all the security checks. Here are some tips and pointers to help you get through quickly:

  • Security personnel will ask to see your travel ID and boarding pass as part of their checks. Tuck them away in a convenient place, so they’re all ready for inspection.
  • Remove your shoes and belt before arriving at the airport security checkpoint. Items like these are not permitted to pass through the body scanner.
  • Make sure your phone, laptop and other electronic devices are easily accessible. These items need to be sent through the X-ray machine separately.
  • When you approach the security checkpoint, you’ll be asked to place all creams, gels and liquids in a separate tray for scanning. Make sure they’re all packed in containers smaller than 3.4 ounces (100 milliliters) and sealed in a clear zip-lock bag.
  • Security personnel will likely tell you to take off your shoes for the body scanner. Choose a pair that you can slip off easily. There’s nothing more irritating than having to do your laces up over and over again.
  • Pocketknives and corkscrews are not permitted on board the aircraft. Tuck them away in your checked luggage to avoid them being confiscated at the airport security checkpoint.

Plane Tickets To Sikeston

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Sikeston. Browse through our inventory to explore a wide range of cheap flights to Sikeston to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Sikeston as you anxiously await to exit the plane and explore what Sikeston has to offer. Considering all the amazing local food and culture in Sikeston, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Sikeston to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Sikeston without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Sikeston with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Sikeston today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.