Cheap Flight Deals to Sikeston MO from CA $231
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How to find cheap flights to Sikeston?
The cheapest prices found with in the last 7 days for return flights were CA $195 and CA $231 for one-way flights to Sikeston for the period specified. Prices and availability are subject to change. Additional terms apply
| Origin | Destination | Travel dates | Flights from* |
|---|---|---|---|
| ATL | St. Louis | August 28 to August 31 | CA $195 |
| SEA | St. Louis | September 21 to September 30 | CA $394 |
| LAX | St. Louis | September 4 to September 8 | CA $585 |
| DEN | St. Louis | August 23 to August 27 | CA $1,087 |
| DFW | St. Louis | September 24 to September 27 | CA $1,098 |
| EWR | St. Louis | July 9 to July 13 | CA $1,148 |
| TPA | St. Louis | August 14 to August 24 | CA $1,276 |
| PHL | St. Louis | August 28 to August 30 | CA $1,305 |
Your guide to flights to Sikeston, MO
American Airlines, Delta fly to Sikeston, so use Travelocity to search, find, and compare some truly tempting deals from the 2 airlines—that way you can be sure you’ve found the best deal for you. A flight to Sikeston MO currently costs between CA $195 and CA $2,065. Prices vary, but for the best fares, travel in September when prices are at their lowest.
Top tips for finding cheap flights to Sikeston
The cheapest flight for a round trip to Sikeston is currently CA $195. When you search for flights to Sikeston, enter your preferred travel dates then click on ‘flexible dates’ to compare cheap flight tickets to Sikeston for nearby days. The cheapest month to travel to Sikeston is September from our list of deals available.
But if you’re flexible about when you travel, you can find great deals on flights across the year. If you’re planning a vacation, you can save more on Travelocity when you bundle flights with car rental and hotel bookings, too. Many airlines currently offer flexible booking options, so look for flights offering no change fees.
How to cancel flights to Sikeston
We know plans change, that’s why at Travelocity, we make it as easy as possible for you to cancel or amend your plane tickets. Go to My Trips, enter your itinerary number, then follow the instructions. Many airlines let you cancel flights online free of charge if you booked it in the last 24 hours. Visit Customer Service for more advice.
Why you should book your flight to Sikeston with Travelocity
We have top deals on plane tickets even for last minute flights to Sikeston, so you can simply type in your travel dates and compare our best prices. Booking with Travelocity means you get flexible cancellation options, 24/7 support, and, thanks to our Price Match Promise, if the airfare drops after you book, you can get a refund! Whether you’re planning a business trip, weekend getaway, or a family vacation—let Travelocity get you to Sikeston for less.
Find The Perfect Hotel For After Your Flight
Amazing Place to Stay After Flight to Sikeston
Pear Tree Inn Cape Girardeau West
"The staff was extremely friendly. The charger in my room didn't work and the front desk worker allowed me to borrow one. She was extremely helpful. Breakfast was really good and my room was very clean. Bed was comfy and I had everything I needed. Would definitely stay again."
Reviewed on Jun 21, 2026
Days Inn and Suites by Wyndham Sikeston
"Rooms are nice and clean although fixtures could be updated. There is no central air and heat, room is cooled by a wall unit. Room was extremely hot when I first entered."
Reviewed on Jun 24, 2026
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
"Good place, and good breakfast."
Reviewed on Jun 26, 2026
Eagle Inn Charleston
"Great"
Reviewed on Apr 14, 2026
Luxury Hotels in Sikeston
Days Inn and Suites by Wyndham Sikeston
"Rooms are nice and clean although fixtures could be updated. There is no central air and heat, room is cooled by a wall unit. Room was extremely hot when I first entered."
Reviewed on Jun 24, 2026
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
"This was a great place to stay in the historical downtown Cape area! The location was very convenient to many shops and restaurants and the property was very well taken care of and clean. We look forward to staying here again!"
Reviewed on Jun 18, 2026
Quality Inn Cape Girardeau North
"At 915 pm on a Friday night maintenance was using a hammer drill in concrete...just irritating and very loud!"
Reviewed on Jun 22, 2026
Drury Inn & Suites Sikeston, MO
"Quick check-in. Room was very clean and nice. Staff was helpful. Would definitely stay here again."
Reviewed on Jun 28, 2026
Family Friendly Hotels in Sikeston
Drury Inn & Suites Sikeston, MO
"Quick check-in. Room was very clean and nice. Staff was helpful. Would definitely stay here again."
Reviewed on Jun 28, 2026
Best Western Plus Sikeston I-55
"The staff are really nice and friendly. Breakfast is very good too. Pretty close to a convenience store. Only problem was the musty smell through the hallways and into the room. We had to fan out the room before staying inside for too long. We also saw a dead cockroach on the window."
Reviewed on Jun 28, 2026
Drury Inn & Suites Cape Girardeau
"I was driving north to WI from South AL for work and needed a somewhat halfway stop, as a solo traveler I recommend this hotel. Easy to get to and felt safe at the hotel and the surrounding areas. I even walked over to Outback Steakhouse for dinner with no issues. Friendly and helpful front desk ..."
Reviewed on Jun 24, 2026
Comfort Suites Jackson-Cape Girardeau
"We stayed at Comfort Suites in Jackson, Missouri, for two nights and had a very pleasant experience overall. The rooms could use a few cosmetic updates and minor touch-ups, but they were clean, comfortable, and well-maintained where it mattered most. The staff was friendly, welcoming, and helpful ..."
Reviewed on Jun 21, 2026
Best Sikeston Flight and Hotel Packages
Sikeston flight + hotel packages - economy flights
Need a car after flight to Sikeston?
Economy
Compact
Midsize
SUV
Frequently asked questions
Plane Tickets To Sikeston
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Sikeston. Browse through our inventory to explore a wide range of cheap flights to Sikeston to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Sikeston as you anxiously await to exit the plane and explore what Sikeston has to offer. Considering all the amazing local food and culture in Sikeston, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Sikeston to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Sikeston without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Sikeston with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Sikeston today!