Find and compare 4 Star hotels in Palermo

Name: Central Palace Hotel Federico II
Price range: CA $217

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Featured Palermo 4 Star hotels

Astoria Palace Hotel

Via Montepellegrino 62 Palermo PA

Fully refundableReserve now, pay when you stay

CA $97

CA $121 total

Sep 8 - Sep 9

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...

7.2/10 Good! (1,001 reviews)

"Thank you , for the comfortable stay"

Reviewed on Aug 13, 2026

Grand Hotel Piazza Borsa

Via dei Cartari 18 Palermo PA

Fully refundableReserve now, pay when you stay

CA $223

CA $260 total

Aug 18 - Aug 19

includes taxes & fees

Book a stay at this spa hotel in Palermo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms in ...

9/10 Wonderful! (943 reviews)

"Good hotel"

Reviewed on Aug 13, 2026

Hotel Politeama

Piazza Ruggiero Settimo,15 Palermo PA

CA $244

CA $283 total

Sep 6 - Sep 7

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...

9.4/10 Exceptional! (627 reviews)

"Excellent location, wonderful staff"

Reviewed on Aug 15, 2026

Quintocanto Hotel and Spa

Corso Vittorio Emanuele, 310 Palermo PA

Fully refundableReserve now, pay when you stay

CA $184

CA $217 total

Sep 6 - Sep 7

includes taxes & fees

Book a stay at this spa hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular ...

8.2/10 Very good! (543 reviews)

"Wouldn’t recommend staying here. Not the cleanest and lots of ants. Bed was also uncomfortable with really cheap linens and pillows."

Reviewed on Aug 5, 2026

Cristal Hotel Palermo

Via Roma 477 A Palermo PA

Fully refundableReserve now, pay when you stay

CA $182

CA $215 total

Aug 23 - Aug 24

includes taxes & fees

Stay at this hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Palermo Harbour and Mondello Beach are located ...

8.2/10 Very good! (836 reviews)

"This should NOT be a 4 star hotel! We saw the largest cockroach in our room and left at midnight. Not to mention that the quality of the hotel should not qualify this for a 4 star hotel (I’d guess this is 2 star). We had to find another hotel in the middle of the night with our kids, it was not a ..."

Reviewed on Aug 11, 2026

President Hotel Palermo

Via Francesco Crispi 230 Palermo PA

Fully refundableReserve now, pay when you stay

CA $145

CA $206 total

Sep 2 - Sep 3

includes taxes & fees

Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Popular attractions Palermo Harbour and ...

8.2/10 Very good! (631 reviews)

"Rooms are clean and staff are very friendly."

Reviewed on Aug 4, 2026

NH Palermo

Foro Italico Palermo PA

Fully refundableReserve now, pay when you stay

CA $257

CA $297 total

Aug 25 - Aug 26

includes taxes & fees

Stay at this hotel in Palermo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...

8.2/10 Very good! (1,003 reviews)

"We went in August. Extremely hot. The AC didn't go below 20C. I guess that was the lowest. Other than that the property and hotel were great!!"

Reviewed on Aug 16, 2026

Hotel Plaza Opera

Via Gallo Nicolo' 2 Palermo PA

Fully refundableReserve now, pay when you stay

CA $203

CA $238 total

Aug 25 - Aug 26

includes taxes & fees

Book a stay at this spa hotel in Palermo. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...

8.6/10 Excellent! (670 reviews)

"The room wasn’t clean, there was soot under the desk. The staff was ok, they did the minimal in terms of answering questions."

Reviewed on Aug 16, 2026

Eurostars Centrale Palace

Via Vittorio Emanuele, 327 Palermo PA

Fully refundableReserve now, pay when you stay

CA $184

CA $217 total

Aug 25 - Aug 26

includes taxes & fees

Book a stay at this luxury hotel in Palermo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...

8.4/10 Very good! (1,000 reviews)

"In the middle of everything"

Reviewed on Aug 5, 2026

Central Palace Hotel Federico II

Via Principe Di Granatelli 60 Palermo PA

CA $217

CA $253 total

Aug 18 - Aug 19

includes taxes & fees

Book a stay at this spa hotel in Palermo. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Popular attractions Palermo Harbour and Mondello Beach ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Palermo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Palermo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Palermo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Palermo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.