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Featured Palermo 4 Star hotels

Hotel Politeama

Hotel Politeama

4 out of 5
Piazza Ruggiero Settimo,15 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $238 per night from Jun 16 to Jun 17
CA $238
CA $276 total
Jun 16 - Jun 17
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (555 reviews)
Spacious King bed even it’s written as double. Location is great as well.

Reviewed on May 15, 2026

Opens in a new windowHotel Politeama
Astoria Palace Hotel

Astoria Palace Hotel

4 out of 5
Via Montepellegrino 62 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $86 per night from Jun 14 to Jun 15
CA $86
CA $109 total
Jun 14 - Jun 15
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, 2 restaurants, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,001 reviews)
Room was basic and not new or too clean. Air con didn’t work and area around hotel was not pleasant. Will not recommend

Reviewed on May 10, 2026

Opens in a new windowAstoria Palace Hotel
San Paolo Palace Hotel

San Paolo Palace Hotel

4 out of 5
Via Messina Marine, 91 Palermo PA
The price is CA $154 per night from May 29 to May 30
CA $154
CA $184 total
May 29 - May 30
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (752 reviews)
Be under no dellusions, at very best a 2-star hotel. Currently undergoing major renovation with severe disruption & noise. Some rooms renovated, many ongoing & others in bad repair, decades out of date. Initially given a South facing refurbished room, but no air condtioning. Apparently council prevent ...

Reviewed on Apr 28, 2026

Opens in a new windowSan Paolo Palace Hotel
Cristal Hotel Palermo

Cristal Hotel Palermo

4 out of 5
Via Roma 477 A Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $169 per night from May 24 to May 25
CA $169
CA $200 total
May 24 - May 25
includes taxes & fees
Stay at this hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Palermo Harbour and Mondello Beach are located ...
8.2/10 Very Good! (812 reviews)
Under Construction: be sure to call to see if construction is still happening when you plan to stay. Construction starts by 8:00 a.m. and you will experience the hammering and drilling noises of it even if you have an inside room. We had an inside room; there was no traffic noise at all. Wifi was ...

Reviewed on Apr 27, 2026

Opens in a new windowCristal Hotel Palermo
NH Palermo

NH Palermo

4 out of 5
Foro Italico Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $256 per night from Jun 7 to Jun 8
CA $256
CA $296 total
Jun 7 - Jun 8
includes taxes & fees
Stay at this hotel in Palermo. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.2/10 Very Good! (1,002 reviews)
The property was centrally located

Reviewed on May 15, 2026

Opens in a new windowNH Palermo
Grand Hotel Piazza Borsa

Grand Hotel Piazza Borsa

4 out of 5
Via dei Cartari 18 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $212 per night from Jun 7 to Jun 8
CA $212
CA $248 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this spa hotel in Palermo. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (899 reviews)
An excellent place to stay. The location is perfect to visit main atracciones of Palermo. Breakfast was super.

Reviewed on May 14, 2026

Opens in a new windowGrand Hotel Piazza Borsa
Mercure Hotel Palermo Centro

Mercure Hotel Palermo Centro

4 out of 5
Via Stabile Mariano 112 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $129 per night from Jun 7 to Jun 8
CA $129
CA $157 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful ...
Opens in a new windowMercure Hotel Palermo Centro
Splendid Hotel La Torre

Splendid Hotel La Torre

4 out of 5
Via Piano Gallo 11 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $278 per night from May 18 to May 19
CA $278
CA $320 total
May 18 - May 19
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our reviews. ...
7.8/10 Good! (483 reviews)
Everythinf is perfect! specially breakfast and the view

Reviewed on May 9, 2026

Opens in a new windowSplendid Hotel La Torre
Casena Dei Colli, Sure Hotel Collection by Best Western

Casena Dei Colli, Sure Hotel Collection by Best Western

4 out of 5
Via Villa Rosato 20-22 Palermo PA
Fully refundableReserve now, pay when you stay
The price is CA $116 per night from May 24 to May 25
CA $116
CA $142 total
May 24 - May 25
includes taxes & fees
Book a stay at this business-friendly hotel in Palermo. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Palermo Harbour and Mondello ...
8.2/10 Very Good! (924 reviews)
Breakfast was great! Lovely buffet breakfast. Room was clean and staff were pleasant.

Reviewed on May 16, 2026

Opens in a new windowCasena Dei Colli, Sure Hotel Collection by Best Western
Ambasciatori Hotel

Ambasciatori Hotel

4 out of 5
Via Roma 111 Palermo PA
The price is CA $217 per night from May 28 to May 29
CA $217
CA $253 total
May 28 - May 29
includes taxes & fees
Stay at this hotel in Palermo. Enjoy free WiFi, a rooftop terrace, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (1,003 reviews)
The bed and pillows are most comfortable. The bathroom is spacious with a great shower. Overall, it's a good hotel for the price, although the entire place needs a "facelift".

Reviewed on May 10, 2026

Opens in a new windowAmbasciatori Hotel
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4 Star Hotels Palermo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Palermo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Palermo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Palermo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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