Find and compare 5 Star hotels in Panama City
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Featured Panama City 5 Star hotels

Hotel Riu Plaza Panama
Overall experience for this property was awesome. Food, staff, drinks, entertainment were all phenomenal. Pool was small…
Reviewed on Jan 4, 2026

Waldorf Astoria Panama
Everything was perfect. Hotel staff was attentive, great amenities, and centrally located.
Reviewed on Jan 5, 2026

W Panama
The room was beautiful with a breathtaking view. The shower flow and hot water could be better along with the drainage system, but that was the only small flaws. We would certainly stay again!
Reviewed on Jan 3, 2026

JW Marriott Panama
Great Hotel and great staff
Reviewed on Jan 7, 2026

Sofitel Legend Casco Viejo, Panama City
The staf, the people on the main entrance door, the concierne, everything is perfect.
Reviewed on Jan 5, 2026

Hilton Panama
Safe area
Reviewed on Jan 2, 2026

The Westin Playa Bonita Panama
Beautiful hotel with amazing view of the ocean. Good food, comfortable rooms. Close to the city and easy transportation to the airport. It would be nice to have OTC medicines at the convenience store inside the resort in case of an emergency.
Reviewed on Jan 7, 2026

Renaissance Panama City Hotel
Yes
Reviewed on Jan 6, 2026

Bristol Panama, a Registry Collection Hotel
Courteous staff, wonderful breakfast and a peaceful stay.
Reviewed on Jan 1, 2026

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
this is the best place to stay near the airport. great rooms, fantastic staff. The best breakfast ever! this is not my first time at Santa Maria and definitely not the last!!!
Reviewed on Dec 11, 2025
Five Star Hotels in Panama City
Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Panama City to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Panama City 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Panama City before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
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