Cheap Flight Deals to Southeast Missouri MO from CA $244
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How to find cheap flights to Southeast Missouri?
The cheapest prices found with in the last 7 days for return flights were CA $421 and CA $244 for one-way flights to Southeast Missouri for the period specified. Prices and availability are subject to change. Additional terms apply
Your guide to flights to Southeast Missouri, MO
Air Canada, Alaska Airlines, Delta fly to Southeast Missouri, so use Travelocity to search, find, and compare some truly tempting deals from the 4 airlines—that way you can be sure you’ve found the best deal for you. A flight to Southeast Missouri MO currently costs between CA $421 and CA $464. Prices vary, but for the best fares, travel in September when prices are at their lowest.
Top tips for finding cheap flights to Southeast Missouri
The cheapest flight for a round trip to Southeast Missouri is currently CA $421. When you search for flights to Southeast Missouri, enter your preferred travel dates then click on ‘flexible dates’ to compare cheap flight tickets to Southeast Missouri for nearby days. The cheapest month to travel to Southeast Missouri is February from our list of deals available.
But if you’re flexible about when you travel, you can find great deals on flights across the year. If you’re planning a vacation, you can save more on Travelocity when you bundle flights with car rental and hotel bookings, too. Many airlines currently offer flexible booking options, so look for flights offering no change fees.
How to cancel flights to Southeast Missouri
We know plans change, that’s why at Travelocity, we make it as easy as possible for you to cancel or amend your plane tickets. Go to My Trips, enter your itinerary number, then follow the instructions. Many airlines let you cancel flights online free of charge if you booked it in the last 24 hours. Visit Customer Service for more advice.
Why you should book your flight to Southeast Missouri with Travelocity
We have top deals on plane tickets even for last minute flights to Southeast Missouri, so you can simply type in your travel dates and compare our best prices. Booking with Travelocity means you get flexible cancellation options, 24/7 support, and, thanks to our Price Match Promise, if the airfare drops after you book, you can get a refund! Whether you’re planning a business trip, weekend getaway, or a family vacation—let Travelocity get you to Southeast Missouri for less.
Find The Perfect Hotel For After Your Flight
Amazing Place to Stay After Flight to Southeast Missouri
Motel 6 Poplar Bluff, MO
Parking is easy and plentiful. Beds and pillows are always comfortable. Staff was friendly and helpful with my questions. Very much recommended.
Reviewed on Jan 7, 2026
Pear Tree Inn Sikeston
Clean and comfy room. Great staff
Reviewed on Jan 6, 2026
Super 8 by Wyndham Farmington
Clean Rooms and Great Staff!!!
Reviewed on Jan 12, 2026
Super 8 by Wyndham Pevely
Awesome
Reviewed on Nov 11, 2025
Luxury Hotels in Southeast Missouri
Super 8 by Wyndham Pevely
Awesome
Reviewed on Nov 11, 2025
Motel 6 Poplar Bluff, MO
Parking is easy and plentiful. Beds and pillows are always comfortable. Staff was friendly and helpful with my questions. Very much recommended.
Reviewed on Jan 7, 2026
Days Inn and Suites by Wyndham Sikeston
It was nice a hotel have to come back sometime
Reviewed on Jan 9, 2026
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Great location, quality bedding and pillows, and other comfortable amenities for a short getaway in historic downtown Cape Girardeau. Excellent value!
Reviewed on Dec 15, 2025
Family Friendly Hotels in Southeast Missouri
Drury Inn & Suites Sikeston, MO
Accommodation
Reviewed on Jan 11, 2026
Pear Tree Inn Sikeston
Clean and comfy room. Great staff
Reviewed on Jan 6, 2026
Best Western Plus Sikeston
Everything was very good from entering to exiting.
Reviewed on Jan 3, 2026
Drury Inn & Suites Cape Girardeau
The room was great!! The beds were sooo soft!! We enjoyed the breakfast and dinners as well. The service during food times was impeccable!! We will try to only stay at Drury from now on!!
Reviewed on Jan 10, 2026
Best Southeast Missouri Flight and Hotel Packages
Southeast Missouri flight + hotel packages - economy flights
Need a car after flight to Southeast Missouri?
Economy
Compact
Midsize
SUV
Frequently asked questions
Plane Tickets To Southeast Missouri
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southeast Missouri. Browse through our inventory to explore a wide range of cheap flights to Southeast Missouri to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southeast Missouri as you anxiously await to exit the plane and explore what Southeast Missouri has to offer. Considering all the amazing local food and culture in Southeast Missouri, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southeast Missouri to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southeast Missouri without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southeast Missouri with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southeast Missouri today!
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