Vacation Homes in O Brien
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Featured Vacation Homes in O Brien

River Run Riviera

Bunkhouse Farm Stay

Peaceful property on the historic Suwannee River.

High Springs Hideaway – 4BR w/ Pool & Bar • Near Springs & UF • Walk to Town

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Private 12 acre Ranch sleeps up to 8 on The Santa Fe River.

Charming 2-bedroom house with WiFi, AC in fantastic Downtown Lake City

New riverfront home across from Rock Bluff Springs on the Suwannee river

The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee

Peaceful Barn Retreat on 7 Private Acres / Near Gainesville and Springs

Cozy 1-bedroom house in delightful High Springs

Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed.
Top trending hotels in O Brien

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Vacation Rentals in O Brien
What kind of vacation do you want in O Brien? The answer to that question will help you choose the right lodging for your stay. The wise wanderer knows that a vacation rental is an essential part of the traveling experience. It’s more than just a place to crash at night—it’s where you wake up in the morning, where you lounge when you’re not exploring, and it’s the starting point for all your adventures. No matter what type of vacation homes strike your fancy, Travelocity has something in O Brien that will speak to you.
Do you want a fully equipped kitchen so you can exercise your culinary mastery and impress your travel buddies? How about a romantic terrace for your anniversary trip? Have you always wished to fall asleep to the sound of waves crashing on the shore? One of our vacation home rentals is bound to add that extra magic to your trip. In fact, we’ve got plenty of options lined up just for you in O Brien, including luxury vacation rentals. On a budget? We can work with your funds and still give you a great place to sleep at night.
Take a look at what we have on offer. You’ll find rentals close to the big tourist draws, as well as rentals that keep you away from the crowd. Consider vacation rentals a little off the beaten path where you can live like a local and discover hidden gems that never make it to the tourist sites. Book through Travelocity and start your getaway today.
O Brien Vacation Homes essential information
Accommodation | 120 Vacation Homes |
|---|---|
Lowest Price | CA $103 |
Highest Price | CA $352 |
Popular accommodation | River Run Riviera, Bunkhouse Farm Stay, Peaceful property on the historic Suwannee River., High Springs Hideaway – 4BR w/ Pool & Bar • Near Springs & UF • Walk to Town, Beautiful 2 story house overlooking the water. Has arcade & Close to the springs, Private 12 acre Ranch sleeps up to 8 on The Santa Fe River., Charming 2-bedroom house with WiFi, AC in fantastic Downtown Lake City, New riverfront home across from Rock Bluff Springs on the Suwannee river, The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee, Peaceful Barn Retreat on 7 Private Acres / Near Gainesville and Springs, Cozy 1-bedroom house in delightful High Springs, Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed. |





