Cheap Flight Deals to Southeast Missouri MO from CA $247

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How to find cheap flights to Southeast Missouri?

The cheapest prices found with in the last 7 days for return flights were CA $281 and CA $247 for one-way flights to Southeast Missouri for the period specified. Prices and availability are subject to change. Additional terms apply

Thu, Nov 13 - Mon, Nov 17
YYZ
Pearson Intl.
STL
Lambert-St. Louis Intl.
CA $361 Roundtrip, found 3 days ago
CA $361
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Nov 13 from Pearson Intl. to Lambert-St. Louis Intl., returning Mon, Nov 17, priced at CA $361 found 3 days ago
OriginDestinationTravel datesFlights from*
EWRSt. LouisDecember 4 to December 11CA $281
LAXSt. LouisNovember 6 to November 9CA $529
*Prices include taxes and fees

Your guide to flights to Southeast Missouri, MO

Delta, American Airlines fly to Southeast Missouri, so use Travelocity to search, find, and compare some truly tempting deals from the 2 airlines—that way you can be sure you’ve found the best deal for you. A flight to Southeast Missouri MO currently costs between CA $281 and CA $529. Prices vary, but for the best fares, travel in November when prices are at their lowest.  

Top tips for finding cheap flights to Southeast Missouri  

The cheapest flight for a round trip to Southeast Missouri is currently CA $281. When you search for flights to Southeast Missouri, enter your preferred travel dates then click on ‘flexible dates’ to compare cheap flight tickets to Southeast Missouri for nearby days.  The cheapest month to travel to Southeast Missouri is November from our list of deals available.  

But if you’re flexible about when you travel, you can find great deals on flights across the year. If you’re planning a vacation, you can save more on Travelocity when you bundle flights with car rental and hotel bookings, too. Many airlines currently offer flexible booking options, so look for flights offering no change fees.   

How to cancel flights to Southeast Missouri 

We know plans change, that’s why at Travelocity, we make it as easy as possible for you to cancel or amend your plane tickets. Go to My Trips, enter your itinerary number, then follow the instructions. Many airlines let you cancel flights online free of charge if you booked it in the last 24 hours. Visit Customer Service for more advice.  

Why you should book your flight to Southeast Missouri with Travelocity 

We have top deals on plane tickets even for last minute flights to Southeast Missouri, so you can simply type in your travel dates and compare our best prices. Booking with Travelocity means you get flexible cancellation options, 24/7 support, and, thanks to our Price Match Promise, if the airfare drops after you book, you can get a refund! Whether you’re planning a business trip, weekend getaway, or a family vacation—let Travelocity get you to Southeast Missouri for less. 

Find The Perfect Hotel For After Your Flight

Amazing Place to Stay After Flight to Southeast Missouri

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
The price is CA $111 per night from Oct 23 to Oct 24
CA $111
CA $117 total
Oct 23 - Oct 24
includes taxes & fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,014 reviews)
"Clean Room"

Reviewed on Oct 12, 2025

Opens in a new windowMotel 6 Poplar Bluff, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
The price is CA $105 per night from Oct 23 to Oct 24
CA $105
CA $121 total
Oct 23 - Oct 24
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,012 reviews)
"The Pear Tree was clean, comfortable, and the staff were extremely friendly!"

Reviewed on Oct 13, 2025

Opens in a new windowPear Tree Inn Sikeston
Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington

2 out of 5
930 Valley Creek Dr, Farmington, MO
The price is CA $76 per night from Oct 21 to Oct 22
CA $76
CA $86 total
Oct 21 - Oct 22
includes taxes & fees
Book a stay at this business-friendly motel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (594 reviews)
"Check in staff seemed a little overwhelmed and took them a minute to find my reservation. Could’ve been a little more friendly."

Reviewed on Oct 14, 2025

Opens in a new windowSuper 8 by Wyndham Farmington
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Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely

2 out of 5
1711 Highway Z, Pevely, MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (827 reviews)
Adequate
"Hotel is in rough shape…but if you just need a place to sleep for the night it will fulfill that. Hotel needs a major revamping."

Reviewed on May 17, 2025

Get rates
Opens in a new windowSuper 8 by Wyndham Pevely
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Southeast Missouri

Super 8 by Wyndham Pevely

Super 8 by Wyndham Pevely

2 out of 5
1711 Highway Z, Pevely, MO
Book a stay at this business-friendly motel in Pevely. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Pevely Park and Sun Valley Park ...
5.6/10 (827 reviews)
Adequate
"Hotel is in rough shape…but if you just need a place to sleep for the night it will fulfill that. Hotel needs a major revamping."

Reviewed on May 17, 2025

Get rates
Opens in a new windowSuper 8 by Wyndham Pevely
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N, Poplar Bluff, MO
The price is CA $111 per night from Oct 23 to Oct 24
CA $111
CA $117 total
Oct 23 - Oct 24
includes taxes & fees
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,014 reviews)
"Clean Room"

Reviewed on Oct 12, 2025

Opens in a new windowMotel 6 Poplar Bluff, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr, Sikeston, MO
The price is CA $88 per night from Nov 16 to Nov 17
CA $88
CA $101 total
Nov 16 - Nov 17
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,007 reviews)
"The staff was very professional, kind and accommodating."

Reviewed on Oct 12, 2025

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
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Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

Cape Girardeau
Stay at this apartment in Cape Girardeau. Enjoy free WiFi, a water park, and laundry facilities. Popular attractions Riverfront Park and eDen Spa & Salon are ...
9.8/10 Exceptional! (170 reviews)
"Great placeClean amenities bed comfortable location view all excellent Tea room downstairs a nice extra too"

Reviewed on Sep 21, 2025

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Opens in a new windowHistorical 'Kage House' Short Term Rental located in "Old Town Cape"
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Southeast Missouri

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner, Sikeston, MO
The price is CA $126 per night from Nov 13 to Nov 14
CA $126
CA $145 total
Nov 13 - Nov 14
includes taxes & fees
Stay at this 3-star business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,008 reviews)
"Clean. Happy hour at 530, decent breakfast options"

Reviewed on Oct 16, 2025

Opens in a new windowDrury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 out of 5
2602 E Malone Avenue, Sikeston, MO
The price is CA $105 per night from Oct 23 to Oct 24
CA $105
CA $121 total
Oct 23 - Oct 24
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,012 reviews)
"The Pear Tree was clean, comfortable, and the staff were extremely friendly!"

Reviewed on Oct 13, 2025

Opens in a new windowPear Tree Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive, Sikeston, MO
The price is CA $118 per night from Nov 13 to Nov 14
CA $118
CA $134 total
Nov 13 - Nov 14
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.2/10 Very Good! (1,008 reviews)
"Clean and roomy room. Friendly and helpful staff. Great breakfast."

Reviewed on Oct 16, 2025

Opens in a new windowBest Western Plus Sikeston
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Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive, Cape Girardeau, MO
The price is CA $126 per night from Oct 23 to Oct 24
CA $126
CA $142 total
Oct 23 - Oct 24
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
9.4/10 Exceptional! (1,003 reviews)
Pleasant surprise in Cape Girardeau
"Very clean and comfortable. Good value for the money. Restaurants close by, some within walking distance."

Reviewed on Oct 6, 2025

Opens in a new windowDrury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Southeast Missouri Flight and Hotel Packages

Southeast Missouri flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $1,231, price is now CA $854 per person
CA $854
per person
Nov 17 - Nov 21
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
The Cheshire

The Cheshire

4 out of 5
Price was CA $1,442, price is now CA $1,159 per person
CA $1,159
per person
Nov 17 - Nov 21
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport

2.5 out of 5
Price was CA $1,247, price is now CA $1,009 per person
CA $1,009
per person
Nov 17 - Nov 21
found 21 hours ago
Roundtrip non-stop flight included
Toronto (YYZ) to St. Louis (STL)
Don't see what you're looking for?
See all available trips from Toronto to Southeast Missouri
View all trips

Need a car after flight to Southeast Missouri?

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Frequently asked questions

How much is the cheapest flight to Southeast Missouri?
A roundtrip flight to Southeast Missouri cost as little as CA $281 over the last seven days. Once you've chosen your travel dates, we'll help you find an amazing deal. This price was available on Travelocity for flights to Southeast Missouri departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly to Southeast Missouri?
Be sure to leave November empty in your calendar, because it's the most affordable month to travel to Southeast Missouri. That's based on Travelocity's direct flight demand from January to December last year. With the cash you save, you can go on a spending spree, go for a fancy dinner or whatever makes you happy.
How can I check my flight status to Southeast Missouri?
Make the most of Travelocity's handy portal, Trips. You'll find just about everything related to your flight to Southeast Missouri here, including details about flight status, gate numbers and more. Look for Trips at the top of the Travelocity homepage. Create your free account and get the answers you need. Or you can access your itinerary while you're on the go and get real-time travel updates through the Travelocity app. You'll find all your itineraries in one place, making it a cinch to share details with any members of your family flying with you.
How do I find the best deals on flights to Southeast Missouri?
Being flexible with your dates is one of the best ways to snag an awesome deal. Travelocity makes it a cinch to find your perfect fare through the "Flexible dates" feature. First, search for your Southeast Missouri flight, then compare prices for surrounding dates by hitting the Flexible dates box above. Booking in advance and avoiding peak travel periods are other steps you can take. In the last seven days, the lowest price for a return flight to Southeast Missouri was CA $281. This price was available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
Why should I book my flight to Southeast Missouri with Travelocity?
If you're looking for cheap flights to Southeast Missouri, you'll discover some tempting deals with Travelocity. From cheap family flights with low-cost airlines to flexible tickets, we can help you. Enjoy a worry-free trip with our 24/7 customer support, Price Match Guarantee and free cancellations with most hotels. Start packing your bags and get ready to jump on a plane to this interesting destination.
How much is a flight to Southeast Missouri on average?
Airfares for roundtrip flights to Southeast Missouri were priced between CA $281 and CA $529 in the last seven days. The minute you spot a good deal, snap it up and get ready for your dream getaway with Travelocity. These prices were available on Travelocity for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Plane Tickets To Southeast Missouri

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Southeast Missouri. Browse through our inventory to explore a wide range of cheap flights to Southeast Missouri to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Southeast Missouri as you anxiously await to exit the plane and explore what Southeast Missouri has to offer. Considering all the amazing local food and culture in Southeast Missouri, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Southeast Missouri to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Southeast Missouri without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Southeast Missouri with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Southeast Missouri today!

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.