Photo by Amber Palmer
Book a hotel near Mayo Clinic Florida, Southside
Wander Wisely with exceptional service, 24/7 support
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Hotels near Mayo Clinic Florida

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
14390 Mayo Boulevard, Jacksonville, FL
Free cancellation
Reserve now, pay when you stay
0.3 km from Mayo Clinic Florida
The price is CA $222 per night
CA $222
CA $252 total
Aug 16 - Aug 17
includes taxes & fees
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions St. Johns Town Center and TPC Sawgrass are located nearby.
Pool
Parking included

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
Free cancellation
Reserve now, pay when you stay
1.08 km from Mayo Clinic Florida
The price is CA $241 per night
CA $241
CA $274 total
Aug 15 - Aug 16
includes taxes & fees
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and TPC Sawgrass are located nearby.
Pool
Breakfast included

Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard
1.21 km from Mayo Clinic Florida
Book a stay at this family-friendly vacation home in Jacksonville Beach. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions St. Johns Town Center and TPC Sawgrass are located nearby.
Kitchen
Washer

Fancy private pool home in Jax beach
1.25 km from Mayo Clinic Florida
The price is CA $366 per night
CA $366
CA $725 total
Aug 11 - Aug 12
includes taxes & fees
Stay at this vacation home in Jacksonville Beach. Enjoy private pools, laundry facilities, and patios. Popular attractions St. Johns Town Center and TPC Sawgrass are located nearby.
Pool
Kitchen

Beautiful 3 bedroom, 2 bathroom Beach Bungalow in Jacksonville Beach!
2.16 km from Mayo Clinic Florida
The price is CA $160 per night
CA $160
CA $454 total
Aug 7 - Aug 8
includes taxes & fees
Stay at this vacation home in Jacksonville Beach. Enjoy free WiFi, a water park, and a garden. Popular attractions St. Johns Town Center and Windsor Parke Golf Club are located nearby.
Kitchen
Washer

Fun 5 Star Hot Tub/Beaches getaway Near MAYO!
2.49 km from Mayo Clinic Florida
The price is CA $216 per night
CA $216
CA $457 total
Aug 7 - Aug 8
includes taxes & fees
Stay at this vacation home in Jacksonville Beach. Enjoy a garden, laundry facilities, and an in-room coffeemaker. Popular attractions St. Johns Town Center and Windsor Parke Golf Club are located nearby.
Hot tub
Kitchen

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
4791 Windsor Commons Ct, Jacksonville, FL
Free cancellation
2.67 km from Mayo Clinic Florida
The price is CA $172 per night
CA $172
CA $196 total
Aug 16 - Aug 17
includes taxes & fees
Book a stay at this golf hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions St. Johns Town Center and TPC Sawgrass are located nearby.
Pool
Breakfast included

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
13733 Beach Blvd, Jacksonville, FL
Free cancellation
Reserve now, pay when you stay
3.1 km from Mayo Clinic Florida
The price is CA $163 per night
CA $163
CA $185 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions St. Johns Town Center and Windsor Parke Golf Club are located nearby.
Pool
Breakfast included

TownePlace Suites by Marriott Jacksonville East
13741 BEACH BLVD, Jacksonville, FL
Free cancellation
Reserve now, pay when you stay
3.1 km from Mayo Clinic Florida
The price is CA $172 per night
CA $172
CA $195 total
Aug 11 - Aug 12
includes taxes & fees
Stay at this 3-star business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Johns Town Center and Windsor Parke Golf Club are located nearby.
Breakfast included
Pet-friendly

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
1220 Marsh Landing Pkwy, Jacksonville Beach, FL
Free cancellation
Reserve now, pay when you stay
4.16 km from Mayo Clinic Florida
The price is CA $174 per night
CA $174
CA $198 total
Aug 17 - Aug 18
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions TPC Sawgrass and South Beach Park and Sunshine Playground are located nearby.
Pool
Breakfast included

Holiday Inn Express Jacksonville Beach by IHG
1101 Beach Blvd, Jacksonville Beach, FL
Free cancellation
4.6 km from Mayo Clinic Florida
The price is CA $168 per night
CA $168
CA $191 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Gonzales Park and Players by the Sea are located nearby.
Pool
Breakfast included

Margaritaville Jacksonville Beach
715 1st St N, Jacksonville Beach, FL
Free cancellation
Reserve now, pay when you stay
5.88 km from Mayo Clinic Florida
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the bar in our reviews. Popular attractions Jacksonville Beach Pier and Northeast Florida Beaches are located nearby.
Pool
Free WiFi
Don't see what you're looking for?
See all available properties in Mayo Clinic Florida
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
About Mayo Clinic Florida Hotels Near Attractions
Do you have a full travel itinerary while visiting Mayo Clinic Florida? Don't waste your time commuting too far from Mayo Clinic Florida area attractions.
Mayo Clinic Florida hotels essential information
Accommodation | 1,865 hotels |
---|---|
Lowest Price | CA $160 |
Highest Price | CA $366 |
Popular hotels | Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Fancy private pool home in Jax beach, Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard, Margaritaville Jacksonville Beach, Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG, TownePlace Suites by Marriott Jacksonville East, Beautiful 3 bedroom, 2 bathroom Beach Bungalow in Jacksonville Beach!, Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, Fun 5 Star Hot Tub/Beaches getaway Near MAYO!, Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area, Holiday Inn Express Jacksonville Beach by IHG |
Recent Mayo Clinic Florida hotel reviews by fellow wanderers

Margaritaville Jacksonville Beach
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Service was great. No breakfast option, but dinner was great."
A verified traveller stayed at Margaritaville Jacksonville Beach
Types of hotels
Hotels near…
Areas of Mayo Clinic Florida
Most popular
Hotels
- Holiday Inn Express Winnipeg Airport - Polo Park by IHG
- Pod Hotels Alberta
- All Inclusive Resorts & Hotels in Bodrum
- Condos Ontario
- Hotels in Grand Falls
- Caravan Inn Motel
- Motel 6 Grande Prairie, AB
- Hotels near United States Consulate General Montréal
- Motels Newfoundland
- Convention Center Hotels in Downtown Ottawa
- Hotels in Portofino
- Hotels with Hot Tubs in Saint-Sauveur
- Cabins Gibsons
- Hotels near Highmark Stadium
Flights
- Toronto to Appleton (YYZ - ATW)
- Flights to Alexis Creek
- Flights to Red Deer
- Flights to Kentucky (CVG)
- Flights to McAllen
- Flights to Clearwater Beach
- Flair Airlines Toronto (YYZ) to Las Vegas (LAS) flights
- Spirit Airlines Fort Lauderdale (FLL) to Detroit (DTW) flights
- WestJet Comox (YQQ) to Edmonton (YEG) flights
- Air Canada Delhi (DEL) to Regina (YQR) flights
- WestJet Toronto (YYZ) to Comox (YQQ) flights