Find and compare 4 Star hotels in Florida Keys

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Featured Florida Keys 4 Star hotels

Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
The price is CA $456 per night from Nov 30 to Dec 1
CA $456
CA $611 total
Nov 30 - Dec 1
includes taxes & fees
Book a stay at this luxury hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8/10 Very Good! (1,003 reviews)
Enjoyed a few days with the kids gere

Reviewed on Nov 15, 2025

Opens in a new windowHawks Cay Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
The price is CA $209 per night from Dec 2 to Dec 3
CA $209
CA $329 total
Dec 2 - Dec 3
includes taxes & fees
Book a stay at this beach resort in Islamorada. Enjoy 2 restaurants, a private beach, and 3 bars/lounges. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,266 reviews)
Loved the resort

Reviewed on Nov 21, 2025

Opens in a new windowAmara Cay Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4 out of 5
97000 Overseas Hwy Key Largo FL
Fully refundableReserve now, pay when you stay
The price is CA $357 per night from Dec 15 to Dec 16
CA $357
CA $480 total
Dec 15 - Dec 16
includes taxes & fees
Book a stay at this beach resort in Key Largo. Enjoy 2 outdoor pools, 2 restaurants, and a private beach. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (1,001 reviews)
As always great staff and amenities. I go there as often as I can , always love it. This time it was off season and they upgraded me to an ocean view for my birthday! 😊

Reviewed on Nov 18, 2025

Opens in a new windowBaker's Cay Resort Key Largo, Curio Collection by Hilton
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

4.5 out of 5
97450 Overseas Highway Key Largo FL
Fully refundableReserve now, pay when you stay
The price is CA $337 per night from Dec 1 to Dec 2
CA $337
CA $457 total
Dec 1 - Dec 2
includes taxes & fees
Book a stay at this luxury resort in Key Largo. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,002 reviews)
This resort has it all. I will go back.

Reviewed on Nov 18, 2025

Opens in a new windowPlaya Largo Resort & Spa, Autograph Collection
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4 out of 5
1996 Overseas Highway Marathon FL
Fully refundableReserve now, pay when you stay
The price is CA $276 per night from Dec 1 to Dec 2
CA $276
CA $364 total
Dec 1 - Dec 2
includes taxes & fees
Book a stay at this beach resort in Marathon. Enjoy free WiFi, 4 outdoor pools, and a full-service spa. Our guests praise the pool and the restaurant in our ...
8.8/10 Excellent! (1,275 reviews)
Room was clean and the parking was easy.

Reviewed on Nov 17, 2025

Opens in a new windowFaro Blanco Resort & Yacht Club Marathon, Curio by Hilton
Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
The price is CA $344 per night from Dec 4 to Dec 5
CA $344
CA $482 total
Dec 4 - Dec 5
includes taxes & fees
Book a stay at this beach hotel in Islamorada. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,008 reviews)
Very nicely refurbished resort, rooms finished to high quality. Really struggled to find high quality accommodation on the Keys, this one ticks all the boxes. Spacious and well laid out resort, great on site activities, nice food options and great staff

Reviewed on Nov 20, 2025

Opens in a new windowIslander Resort
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

4 out of 5
2600 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
The price is CA $412 per night from Dec 7 to Dec 8
CA $412
CA $555 total
Dec 7 - Dec 8
includes taxes & fees
Book a stay at this beach hotel in Marathon. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the pool and the helpful staff in our reviews. ...
8.8/10 Excellent! (1,001 reviews)
Excellent!!

Reviewed on Nov 21, 2025

Opens in a new windowTranquility Bay Beachfront Hotel and Resort
La Siesta Resort & Villas

La Siesta Resort & Villas

4 out of 5
80241 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
The price is CA $190 per night from Nov 30 to Dec 1
CA $190
CA $308 total
Nov 30 - Dec 1
includes taxes & fees
Book a stay at this beach resort in Islamorada. Enjoy a private beach, a marina, and breakfast (surcharge). Our guests praise the helpful staff and the spacious ...
8.6/10 Excellent! (1,000 reviews)
This was the cutest little resort right in the beach! Peaceful and relaxing and the staff was amazingly friendly!!! Would definitely recommend it to anyone. Our room was clean and big and the beds were comfy. Only issue was the ac didn't seem consistent and the fan blower was like a tornado .... ...

Reviewed on Nov 18, 2025

Opens in a new windowLa Siesta Resort & Villas
Villas At Hawks Cay Resort

Villas At Hawks Cay Resort

4 out of 5
61 Hawks Cay Boulevard Marathon FL
Book a stay at this luxury resort in Marathon. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Popular attractions Little Conch Key and Walkers Island ...
8.4/10 Very Good! (145 reviews)
The resort must have been in the off season, as we mostly had the pools to ourselves some days, which was a beautiful experience! The villa was fresh and spotless and the staff at the resort were friendly and attentive! This is why we come back every year!

Reviewed on Nov 1, 2025

Opens in a new windowVillas At Hawks Cay Resort
The Islands of Islamorada

The Islands of Islamorada

4 out of 5
82779 Old Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
The price is CA $987 per night from Nov 30 to Dec 1
CA $987
CA $1,188 total
Nov 30 - Dec 1
includes taxes & fees
Book a stay at this beach villa in Islamorada. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attractions History of Diving Museum and Islamorada ...
9.6/10 Exceptional! (68 reviews)
i like the fact that there's beach area but it was difficult to walk in an out of it due to the rocks. The pool filter could have been cleaned during our stay as there was multiple days of debris caught in the drain trap. would have enjoyed more dining options. Room was available before check in ...

Reviewed on Oct 27, 2025

Opens in a new windowThe Islands of Islamorada
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4 Star Hotels Florida Keys

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Florida Keys 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Florida Keys will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Florida Keys, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Florida Keys hotel reviews by fellow wanderers