Find and compare 4 Star hotels in Mainz
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Featured Mainz 4 Star hotels
NH Collection Frankfurt Spin Tower
Güterplatz 1 Frankfurt Hessen
Fully refundableReserve now, pay when you stay
The price is CA $158 per night from Jul 12 to Jul 13
CA $158
CA $176 total
Jul 12 - Jul 13
includes taxes & fees
Book a stay at this luxury hotel in Frankfurt. Enjoy a full-service spa, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
9/10 Wonderful! (692 reviews)
"Great staff and location."
Reviewed on Jul 8, 2026
Holiday Inn Frankfurt - Alte Oper by IHG
Mainzer Landstrasse 27 Frankfurt
Fully refundable
The price is CA $126 per night from Aug 7 to Aug 8
CA $126
CA $141 total
Aug 7 - Aug 8
includes taxes & fees
Book a stay at this business-friendly hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
9/10 Wonderful! (840 reviews)
"I had a wonderful stay at this hotel. Everything was on point—from the friendly staff and clean rooms to the excellent facilities. The air conditioning worked perfectly, which made the room very comfortable throughout my stay. The hotel was well maintained, and the overall service exceeded my expectations. ..."
Reviewed on Jul 4, 2026
Radisson Blu Hotel, Frankfurt
Franklinstr. 65 Frankfurt HE
Fully refundableReserve now, pay when you stay
The price is CA $163 per night from Jul 25 to Jul 26
CA $163
CA $181 total
Jul 25 - Jul 26
includes taxes & fees
Book a stay at this luxury hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.2/10 Very good! (706 reviews)
"Very nice hotel with amazing staff"
Reviewed on Jul 1, 2026
Hotel Monopol
Mannheimer Str. 11-13 Frankfurt HE
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from Jul 10 to Jul 11
CA $115
CA $146 total
Jul 10 - Jul 11
includes taxes & fees
Book a stay at this business-friendly hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.2/10 Very good! (1,006 reviews)
"We were so pleased with the Hotel Monopol. Our train was delayed so we missed our connection and needed to overnight in Frankfurt. I booked the hotel and when we arrived, the staff was so welcoming and friendly. Check in was easy and our room was huge! The hotel is older but well kept. Our room overlooked ..."
Reviewed on Jul 3, 2026
NH Frankfurt Airport
Moerfelder Strasse 113 Kelsterbach HE
Fully refundableReserve now, pay when you stay
The price is CA $100 per night from Aug 8 to Aug 9
CA $100
CA $113 total
Aug 8 - Aug 9
includes taxes & fees
Book a stay at this business-friendly hotel in Kelsterbach. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the ...
8.8/10 Excellent! (1,054 reviews)
"The staff was great. Breakfast was tasty. The room is OK. the air conditioning is barely working and it’s super hot."
Reviewed on Jul 5, 2026
The Frankfurt Hotel
Am Hauptbahnhof 2 Frankfurt HE
Fully refundableReserve now, pay when you stay
The price is CA $106 per night from Jul 11 to Jul 12
CA $106
CA $119 total
Jul 11 - Jul 12
includes taxes & fees
Book a stay at this business-friendly hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,003 reviews)
"The hotel is situated just across the road from the main railway station. The central business district is a 5 minute flat walk from the hotel and the old town a 12 minute flat walk from the hotel. The staff are very friendly, polite, helpful and professional. The rooms are clean and spacious with ..."
Reviewed on Jun 16, 2026
Melia Frankfurt City
SENCKENBERGANLAGE 13 Frankfurt
Fully refundableReserve now, pay when you stay
The price is CA $192 per night from Jul 26 to Jul 27
CA $192
CA $211 total
Jul 26 - Jul 27
includes taxes & fees
Book a stay at this luxury hotel in Frankfurt. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (569 reviews)
"Brand new hotel very good situated in a peaceful area of Frankfurt. The staff is also very friendly and efficient. The rooms are very comfortable with a nice view of the city. Good quality in meal services."
Reviewed on Jun 9, 2026
Vital Hotel Frankfurt
Niederhofheimer Straße 67 Hofheim am Taunus HE
Fully refundableReserve now, pay when you stay
The price is CA $286 per night from Aug 6 to Aug 7
CA $286
CA $306 total
Aug 6 - Aug 7
includes taxes & fees
Book a stay at this luxury hotel in Hofheim am Taunus. Enjoy free breakfast, free WiFi, and 2 outdoor pools. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (586 reviews)
"Said they had a/c Did not work We asked for a fan the entire time(5 times a day.). No fan- no help with water nothing to help with the heat. Advertising water park with slides. Slides out of order. . The pool was sooooo crowded"
Reviewed on Jun 28, 2026
Capri by Fraser Frankfurt
Europa-Allee 42 Frankfurt
Fully refundableReserve now, pay when you stay
The price is CA $112 per night from Aug 8 to Aug 9
CA $112
CA $127 total
Aug 8 - Aug 9
includes taxes & fees
Book a stay at this luxury hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,004 reviews)
"The Capri by Fraser is an average to above average hotel. The rooms were exceptionally clean,and quiet, but overall the place needs a 'makeover'. The staff was very friendly, accommodating and very professional. One thing that I found self-serving was that you were REQUIRED to join their hospitality/loyalty ..."
Reviewed on Jul 7, 2026
Atrium Hotel Mainz
Flugplatzstr. 44 Mainz RP
Fully refundableReserve now, pay when you stay
The price is CA $149 per night from Jul 30 to Jul 31
CA $149
CA $173 total
Jul 30 - Jul 31
includes taxes & fees
Book a stay at this luxury hotel in Mainz. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the property condition in our reviews. Popular ...
9/10 Wonderful! (403 reviews)
"Parking bad. Rooms old and outdated"
Reviewed on Jun 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
4 Star Hotels Mainz
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Mainz 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Mainz will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Mainz, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Mainz hotel reviews by fellow wanderers
H2 Hotel Mainz
5 out of 5
Posted 11 hours ago
Travelocity Verified Review
"Great location. Spacious rooms. Very quiet. A/C works great."
A verified traveller stayed at H2 Hotel Mainz
