Find and compare 4 Star hotels in Panama City
Wander Wisely with exceptional service, 24/7 support
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Featured Panama City 4 Star hotels

Crowne Plaza Panama Airport by IHG
"Nice hotel. Close to airport with convienent shutttle to and from airport. Great restaurant on property with great staff. Check in staff were extremely friendly and helpful."
Reviewed on Jun 9, 2026

Las Americas Golden Tower Panama
"Loved how central this location is and amazing the staff is, always willing to help and happy to serve"
Reviewed on Jun 9, 2026

Courtyard by Marriott Panama Multiplaza Mall
"Localización"
Reviewed on Jun 9, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
"El gym súper malo viejo sin nada"
Reviewed on Jun 4, 2026

Waymore Hotel Spa & Casino
"Very friendly staff and excellent customer service from registration to housekeeping staff, including those who greet you at the door."
Reviewed on Jun 8, 2026

MARINN PLACE Financial District
"Well-maintained, good breakfast, helpful staff, good central location, free parking"
Reviewed on Jun 9, 2026

Courtyard by Marriott Panama Metromall
"Breakfast was not good"
Reviewed on Jun 9, 2026

Ramada Plaza by Wyndham Panama Punta Pacifica
"Well located hotel, close to good restaurants walking distance. Very comfortable rooms, parking accesible and helpful staff. Great stay."
Reviewed on Jun 9, 2026

Sheraton Grand Panama
"Everything is great"
Reviewed on Jun 9, 2026

Studio Coliving
"Clean, reasonable pricing. Staff was excellent, very responsive. Highly reccomend staying here"
Reviewed on Mar 26, 2026
4 Star Hotels Panama City
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Panama City 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Panama City will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Panama City, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Panama City hotel reviews by fellow wanderers

The Executive Hotel
"Muy buenos los servicios"
Explore More Ways to Travel with Travelocity
- Hotels near Albrook Shopping Mall
- Hotels near Amador Convention Center
- Hotels near ATLAPA Conventions Center
- Pet Friendly Hotels in Bella Vista
- Bethania Hotels
- Casco Viejo Hotels
- Costa del Este Hotels
- El Chorrillo Hotels
- Hotels near El Dorado Mall
- Hotels near Los Pueblos Commercial Center
- Hotels near Marcos A. Gelabert Intl.
- Hotels near Metromall Panama
- Hotels near Multiplaza Pacific Mall
- Farmstay in Panama City
- Apartments in Panama City
- B&B in Panama City
- Cabins in Panama City
- Condos in Panama City
- Cottages in Panama City
- Extended Stay Hotels in Panama City
- Guest Houses in Panama City
- Hostels in Panama City
- Adults Only Resorts & in Panama City
- All Inclusive Resorts & in Panama City
- Beach Resorts & in Panama City
- Boutique Hotels in Panama City
- Casino Resorts & in Panama City
- Cheap Hotels in Panama City
- Convention Center Hotels in Panama City
- Hotels with smoking rooms in Panama City
- Independent Hotels in Panama City
- Luxury Hotels in Panama City
- Pet Friendly Hotels in Panama City
- Spa Resorts & in Panama City
- Waterpark Hotels and Resorts in Panama City
- Panama City Hotels
- Houseboat Rentals in Panama City
- Vacation Homes in Panama City
- Resorts in Panama City
- Treehouses in Panama City
- Villas in Panama City
- Hotels near Panama Viejo
- Punta Paitilla Hotels
- San Antonio Hotels
- Flights to Panama City
- Hahn Air Technologies Bocas del Toro (BOC) to Panama City (PAC) flights
- Flights from Guayaquil to Panama City
- Flights from Lima to Panama City
- Flights from London to Panama City
- Flights from New Orleans to Panama City
- Flights from Santo Domingo to Panama City
- Flights from London to Panama City
- Flights from Fort Lauderdale to Panama City
- Flights from Fort Lauderdale (FLL) to Panama City (PAC)
- Flights from Minneapolis (MSP) to Panama City (PAC)
- Flights from Phoenix (PHX) to Panama City (PAC)
- Flights from San Francisco (SFO) to Panama City (PAC)
- Addcar rental Rental Cars in Panama City
- Auto Rent Rental Cars in Panama City
- Car rentals in Avis 1 Bennett St
- Car rentals near Casco Viejo
- Car rental Panama City
- Convertible Car Rentals in Panama City
- Luxury Car Rentals in Panama City
- Minivan Car Rentals in Panama City
- Movida Rent A Car Rental Cars in Panama City
- Nü Car Rentals Rental Cars in Panama City
- Payless Rental Cars in Panama City
- Thrifty Car Rental Rental Cars in Panama City
- Top Rent a Car Rental Cars in Panama City





